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  1. Background Telomeres, which are composed of repetitive nucleotide sequences at the end of chromosomes, behave as a division clock that measures replicative senescence. Under the normal physiological condition,...

    Authors: Kyung Hyun Lee and Marek Kimmel
    Citation: BMC Genomics 2020 21(Suppl 9):587
    Content type: Research Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  2. Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the u...

    Authors: Siamak Zamani Dadaneh, Paul de Figueiredo, Sing-Hoi Sze, Mingyuan Zhou and Xiaoning Qian
    Citation: BMC Genomics 2020 21(Suppl 9):585
    Content type: Research Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  3. B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind...

    Authors: Xingyu Yang, Christopher M. Tipton, Matthew C. Woodruff, Enlu Zhou, F. Eun-Hyung Lee, Inãki Sanz and Peng Qiu
    Citation: BMC Genomics 2020 21(Suppl 9):583
    Content type: Research Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  4. Mitogen Activated Protein Kinase (MAPK) cascade is a fundamental pathway in organisms for signal transduction. Though it is well characterized in various plants, there is no systematic study of this cascade in...

    Authors: Archita Chatterjee, Abhirup Paul, G. Meher Unnati, Ruchika Rajput, Trisha Biswas, Tamalika Kar, Srijita Basak, Neelam Mishra, Ashutosh Pandey and Anurag Prakash Srivastava
    Citation: BMC Genomics 2020 21:613
    Content type: Research article Published on:

  5. Lysin motif-containing proteins (LYP), which act as pattern-recognition receptors, play central roles in growth, node formation, and responses to biotic stresses. The sequence of Chinese white pear genome (cv....

    Authors: Qiming Chen, Qionghou Li, Xin Qiao, Hao Yin and Shaoling Zhang
    Citation: BMC Genomics 2020 21:612
    Content type: Research article Published on:

  6. Anthocyanins determinate the flower color of many plants. Tobacco is a model plant for studying the molecular regulation of flower coloration. We investigated the mechanism underlying flower coloration in toba...

    Authors: Fangchan Jiao, Lu Zhao, Xingfu Wu, Zhongbang Song and Yongping Li
    Citation: BMC Genomics 2020 21:611
    Content type: Research article Published on:

  9. Phytohormones are the key factors regulating vascular development in plants, and they are also involved in tension wood (TW) formation. Although the theory of hormone distribution in TW formation is widely sup...

    Authors: Yao Xiao, Fei Yi, Juanjuan Ling, Guijuan Yang, Na Lu, Zirui Jia, Junchen Wang, Kun Zhao, Junhui Wang and Wenjun Ma
    Citation: BMC Genomics 2020 21:609
    Content type: Research article Published on:

  10. Sand flies are the vectors of Leishmania parasites. To develop in the sand fly midgut, Leishmania multiplies and undergoes various stage differentiations giving rise to the infective form, the metacyclic promasti...

    Authors: Iliano V. Coutinho-Abreu, Tiago Donatelli Serafim, Claudio Meneses, Shaden Kamhawi, Fabiano Oliveira and Jesus G. Valenzuela
    Citation: BMC Genomics 2020 21:608
    Content type: Research article Published on:

  11. Argeia pugettensis is an isopod species that parasitizes other crustaceans. Its huge native geographic range spans the Pacific from China to California, but molecular data are available only for a handful of spec...

    Authors: Jianmei An, Wanrui Zheng, Jielong Liang, Qianqian Xi, Ruru Chen, Junli Jia, Xia Lu and Ivan Jakovlić
    Citation: BMC Genomics 2020 21:607
    Content type: Research article Published on:

  12. Immune-response (IR) genes have an important role in the defense against highly variable pathogens, and therefore, diversity in these genomic regions is essential for species’ survival and adaptation. Although...

    Authors: Sara Lado, Jean P. Elbers, Mark F. Rogers, José Melo-Ferreira, Adiya Yadamsuren, Jukka Corander, Petr Horin and Pamela A. Burger
    Citation: BMC Genomics 2020 21:606
    Content type: Research article Published on:

  13. Phenotypic performances of livestock animals decline with increasing levels of inbreeding, however, the noticeable decline known as inbreeding depression, may not be due only to the total level of inbreeding, ...

    Authors: Bayode O. Makanjuola, Christian Maltecca, Filippo Miglior, Flavio S. Schenkel and Christine F. Baes
    Citation: BMC Genomics 2020 21:605
    Content type: Research article Published on:

  14. Aedes aegypti is the principle vector of many arboviruses, including dengue virus and Zika virus, which are transmitted when an infected female mosquito takes a blood meal in order to initiate vitellogenesis. Dur...

    Authors: Heather Eggleston and Zach N. Adelman
    Citation: BMC Genomics 2020 21:604
    Content type: Research article Published on:

  15. Seed germination and young seedling growth are important agricultural traits for developing populations of both irrigated and directly seeded rice. Previous studies have focused on the identification of QTLs. ...

    Authors: Jing Yang, Ling Su, Dandan Li, Lixin Luo, Kai Sun, Meng Yang, Fengwei Gu, Aoyun Xia, Yongzhu Liu, Hui Wang, Zhiqiang Chen and Tao Guo
    Citation: BMC Genomics 2020 21:603
    Content type: Research article Published on:

  16. The WD40-repeat containing proteins, including DDB1–CUL4-associated factors (DCAFs), are abundant and conserved proteins that play important roles in different cellular processes including spermatogenesis. DCA...

    Authors: Bhavesh V. Mistry, Maha Alanazi, Hanae Fitwi, Olfat Al-Harazi, Mohamed Rajab, Abdullah Altorbag, Falah Almohanna, Dilek Colak and Abdullah M. Assiri
    Citation: BMC Genomics 2020 21:602
    Content type: Research article Published on:

  17. It has been reported that nitric oxide (NO) could ameliorate cadmium (Cd) toxicity in tall fescue; however, the underlying mechanisms of NO mediated Cd detoxification are largely unknown. In this study, we inv...

    Authors: Huihui Zhu, Honglian Ai, Zhengrong Hu, Dongyun Du, Jie Sun, Ke Chen and Liang Chen
    Citation: BMC Genomics 2020 21:601
    Content type: Research article Published on:

  18. Long non-coding RNAs (lncRNAs) are involved in many fundamental biological processes, such as transcription regulation, protein degradation, and cell differentiation. Information on lncRNA in the melon fly, Zeugo...

    Authors: Wei-Jun Li, Yu-Jia Song, Hong-Liang Han, Hui-Qian Xu, Dong Wei, Guy Smagghe and Jin-Jun Wang
    Citation: BMC Genomics 2020 21:600
    Content type: Research article Published on:

  19. Vibriosis has been implicated in major losses of larvae at shellfish hatcheries. However, the species of Vibrio responsible for disease in aquaculture settings and their associated virulence genes are often varia...

    Authors: Hanna Kehlet-Delgado, Claudia C. Häse and Ryan S. Mueller
    Citation: BMC Genomics 2020 21:599
    Content type: Research article Published on:

  20. Most animals restrict their activity to a specific part of the day, being diurnal, nocturnal or crepuscular. The genetic basis underlying diurnal preference is largely unknown. Under laboratory conditions, Drosop...

    Authors: Mirko Pegoraro, Laura M. M. Flavell, Pamela Menegazzi, Perrine Colombi, Pauline Dao, Charlotte Helfrich-Förster and Eran Tauber
    Citation: BMC Genomics 2020 21:596
    Content type: Research article Published on:

  21. Genomic comparison of Mycoplasma synoviae vaccine strain MS-H and the MS-H parental strain 86,079/7NS established a preliminary profile of genes related to attenuation of MS-H. In this study we aimed to identify ...

    Authors: Somayeh Kordafshari, Pollob Shil, Marc S. Marenda, Olusola M. Olaogun, Barbara Konsak-Ilievski, Jillian Disint and Amir H. Noormohammadi
    Citation: BMC Genomics 2020 21:598
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Genomics 2020 21:718

  22. Antimicrobial resistance is one of our most serious health threats. Antimicrobial peptides (AMPs), effecter molecules of innate immune system, can defend host organisms against microbes and most have shown a l...

    Authors: Haoyi Fu, Zicheng Cao, Mingyuan Li and Shunfang Wang
    Citation: BMC Genomics 2020 21:597
    Content type: Research article Published on:

  23. Feather pecking (FP) in laying hens reduces animal welfare and leads to economic losses for the layer industry. FP is considered a heritable condition that is influenced by dysregulation of neurotransmitter ho...

    Authors: Clemens Falker-Gieske, Andrea Mott, Siegfried Preuß, Sören Franzenburg, Werner Bessei, Jörn Bennewitz and Jens Tetens
    Citation: BMC Genomics 2020 21:595
    Content type: Research article Published on:

  24. The Quaternary had worldwide consequences in forming the contemporary diversity of many populations, species and communities, which is characterized by marked climatic oscillations between glacial and intergla...

    Authors: Kai Song, Bin Gao, Peter Halvarsson, Yun Fang, Ying-Xin Jiang, Yue-Hua Sun and Jacob Höglund
    Citation: BMC Genomics 2020 21:581
    Content type: Research article Published on:

  25. Tissue-specific fat deposition is regulated by a series of complex regulatory mechanisms. Reports indicate that epigenetic regulators, such as circular RNAs (circRNAs), are crucial in diseases progression, ani...

    Authors: Meng Zhang, Yu Han, Yanhui Zhai, Xiangfei Ma, Xinglan An, Sheng Zhang and Ziyi Li
    Citation: BMC Genomics 2020 21:594
    Content type: Research article Published on:

  26. Duplications of large genomic segments provide genetic diversity in genome evolution. Despite their importance, how these duplications are generated remains uncertain, particularly for distant duplicated genom...

    Authors: Javier U. Chicote, Marcos López-Sánchez, Tomàs Marquès-Bonet, José Callizo, Luis A. Pérez-Jurado and Antonio García-España
    Citation: BMC Genomics 2020 21:593
    Content type: Research article Published on:

  27. The DGAT1 gene encodes an enzyme responsible for catalysing the terminal reaction in mammary triglyceride synthesis, and underpins a well-known pleiotropic quantitative trait locus (QTL) with a large influence on...

    Authors: Tania Fink, Thomas J. Lopdell, Kathryn Tiplady, Renee Handley, Thomas J. J. Johnson, Richard J. Spelman, Stephen R. Davis, Russell G. Snell and Mathew D. Littlejohn
    Citation: BMC Genomics 2020 21:591
    Content type: Research article Published on:

  28. Prolonged exposure to elevated free fatty acids induces β-cell failure (lipotoxicity) and contributes to the pathogenesis of type 2 diabetes. In vitro exposure of β-cells to the saturated free fatty acid palmi...

    Authors: Maria Lytrivi, Kassem Ghaddar, Miguel Lopes, Victoria Rosengren, Anthony Piron, Xiaoyan Yi, Henrik Johansson, Janne Lehtiö, Mariana Igoillo-Esteve, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Henrik Ortsäter, Decio L. Eizirik and Miriam Cnop
    Citation: BMC Genomics 2020 21:590
    Content type: Research article Published on:

  29. More than 2500 species belong to the Meloidae family (Coleoptera: Tenebrionoidea), members of which produce the potent defensive blistering agent cantharidin and are commonly known as blister beetles or Spanishfl...

    Authors: Yuan-Ming Wu, Yang-Yang Liu and Xiang-Sheng Chen
    Citation: BMC Genomics 2020 21:589
    Content type: Research article Published on:

  30. Antagonistic co-evolution can drive rapid adaptation in pathogens and shape genome architecture. Comparative genome analyses of several fungal pathogens revealed highly variable genomes, for many species chara...

    Authors: Alice Feurtey, Cécile Lorrain, Daniel Croll, Christoph Eschenbrenner, Michael Freitag, Michael Habig, Janine Haueisen, Mareike Möller, Klaas Schotanus and Eva H. Stukenbrock
    Citation: BMC Genomics 2020 21:588
    Content type: Research article Published on:

  31. Alternative splicing (AS) offers a main mechanism to form protein polymorphism. A growing body of evidence indicates the correlation between splicing disorders and carcinoma. Nevertheless, an overall analysis ...

    Authors: Yuanyuan Zhang, Shengling Ma, Qian Niu, Yun Han, Xingyu Liu, Jie Jiang, Simiao Chen and Haolong Lin
    Citation: BMC Genomics 2020 21:580
    Content type: Research article Published on:

  32. M. morganii is a bacterium frequently associated with urinary infections in humans. While many human strains are sequenced, only the genomes of few poultry strains are available. Here, we performed a detailed cha...

    Authors: Nicola Palmieri, Claudia Hess, Michael Hess and Merima Alispahic
    Citation: BMC Genomics 2020 21:579
    Content type: Research article Published on:

  33. Transcription factor (TF) GAMYB, belonging to MYB family (named after the gene of the avian myeloblastosis virus) is a master gibberellin (GA)-induced regulatory protein that is crucial for development and germin...

    Authors: Anna Bienias, Magdalena Góralska, Piotr Masojć, Paweł Milczarski and Beata Myśków
    Citation: BMC Genomics 2020 21:578
    Content type: Research article Published on:

  34. Drought is one of the most adverse environmental factors limiting crop productions and it is important to identify key genetic determinants for food safety. Calcium-dependent protein kinases (CPKs) are known t...

    Authors: Ge-Zi Li, Han-Xiao Li, Meng-Jun Xu, Peng-Fei Wang, Xiang-Hong Xiao and Guo-Zhang Kang
    Citation: BMC Genomics 2020 21:577
    Content type: Research article Published on:

  35. A balanced constitutional reciprocal translocation (RT) is a mutual exchange of terminal segments of two non-homologous chromosomes without any loss or gain of DNA in germline cells. Carriers of balanced RTs a...

    Authors: Aniek C. Bouwman, Martijn F. L. Derks, Marleen L. W. J. Broekhuijse, Barbara Harlizius and Roel F. Veerkamp
    Citation: BMC Genomics 2020 21:576
    Content type: Research article Published on:

  36. Cotton (Gossypium spp.) is the most important world-wide fiber crop but salt stress limits cotton production in coastal and other areas. Growth regulation factors (GRFs) play regulatory roles in response to salt ...

    Authors: Jun-Feng Cao, Jin-Quan Huang, Xia Liu, Chao-Chen Huang, Zi-Shou Zheng, Xiu-Fang Zhang, Xiao-Xia Shangguan, Ling-Jian Wang, Yu-Gao Zhang, Jonathan F. Wendel, Corrinne E. Grover and Zhi-Wen Chen
    Citation: BMC Genomics 2020 21:575
    Content type: Research article Published on:

  37. Blue mold is a globally important and economically impactful postharvest disease of apples caused by multiple Penicillium spp. There are currently four postharvest fungicides registered for blue mold control, and...

    Authors: Franz J. Lichtner, Verneta L. Gaskins, Kerik D. Cox and Wayne M. Jurick II
    Citation: BMC Genomics 2020 21:574
    Content type: Research article Published on:

  38. ERF transcription factors (TFs) belong to the Apetala2/Ethylene responsive Factor (AP2/ERF) TF family and play a vital role in plant growth and development processes. Capsorubin and capsaicinoids have relative...

    Authors: Jiali Song, Changming Chen, Shuanglin Zhang, Juntao Wang, Zhubing Huang, Muxi Chen, Bihao Cao, Zhangsheng Zhu and Jianjun Lei
    Citation: BMC Genomics 2020 21:573
    Content type: Research article Published on:

  39. As air temperatures increase globally, more and more plants are exposed to heat-stress conditions. Although many studies have explored regulation networks in plants with the aim of improving their heat-stress ...

    Authors: Jiahong Xu, Yao Zheng, Shouqin Pu, Xiujie Zhang, Zhihao Li and Jinhui Chen
    Citation: BMC Genomics 2020 21:572
    Content type: Research article Published on:

  40. The investigation of transcriptome profiles using short reads in non-model organisms, which lack of well-annotated genomes, is limited by partial gene reconstruction and isoform detection. In contrast, long-re...

    Authors: Giuseppe D. Puglia, Andrey D. Prjibelski, Domenico Vitale, Elena Bushmanova, Karl J. Schmid and Salvatore A. Raccuia
    Citation: BMC Genomics 2020 21:317
    Content type: Research article Published on:

  41. Queen failure is a persistent problem in beekeeping operations, but in the absence of overt symptoms it is often difficult, if not impossible, to ascertain the root cause. Stressors like heat-shock, cold-shock...

    Authors: Alison McAfee, Joseph Milone, Abigail Chapman, Leonard J. Foster, Jeffery S. Pettis and David R. Tarpy
    Citation: BMC Genomics 2020 21:571
    Content type: Research article Published on:

  42. Laurel wilt caused by Raffaelea lauricola is a lethal vascular disease of North American members of the Lauraceae plant family. This fungus and its primary ambrosia beetle vector Xyleborus glabratus originated fr...

    Authors: Yucheng Zhang, Junli Zhang, Dan Vanderpool, Jason A. Smith and Jeffrey A. Rollins
    Citation: BMC Genomics 2020 21:570
    Content type: Research article Published on:

  43. Members of the bacterial family Flavobacteriaceae are widely distributed in the marine environment and often found associated with algae, fish, detritus or marine invertebrates. Yet, little is known about the cha...

    Authors: Asimenia Gavriilidou, Johanna Gutleben, Dennis Versluis, Francesca Forgiarini, Mark W. J. van Passel, Colin J. Ingham, Hauke Smidt and Detmer Sipkema
    Citation: BMC Genomics 2020 21:569
    Content type: Research article Published on:

  44. The nosocomial pathogen Enterococcus faecium can survive for prolonged periods of time on surfaces in the absence of nutrients. This trait is thought to contribute to the ability of E. faecium to spread among pat...

    Authors: Vincent de Maat, Sergio Arredondo-Alonso, Rob J. L. Willems and Willem van Schaik
    Citation: BMC Genomics 2020 21:568
    Content type: Research article Published on:

  45. The only licensed live Bacille Calmette-Guérin (BCG) vaccine used to prevent severe childhood tuberculosis comprises genetically divergent strains with variable protective efficacy and rates of BCG-induced adv...

    Authors: Olga Narvskaya, Daria Starkova, Diana Levi, Natalia Alexandrova, Vladimir Molchanov, Ekaterina Chernyaeva, Anna Vyazovaya, Alexander Mushkin, Viacheslav Zhuravlev, Natalia Solovieva, Boris Vishnevskiy and Igor Mokrousov
    Citation: BMC Genomics 2020 21:567
    Content type: Research article Published on:

  46. Common bacterial blight (CBB) caused by Xanthomonas phaseoli pv. phaseoli and Xanthomonas citri pv. fuscans is one of the major threats to common bean crops (Phaseolus vulgaris L.). Resistance to CBB is particula...

    Authors: Justine Foucher, Mylène Ruh, Anne Préveaux, Sébastien Carrère, Sandra Pelletier, Martial Briand, Rémy-Félix Serre, Marie-Agnès Jacques and Nicolas W. G. Chen
    Citation: BMC Genomics 2020 21:566
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Genomics 2020 21:657

  48. Shiga toxin-producing E. coli (STECs) are foodborne pathogens associated with bloody diarrhea and hemolytic uremic syndrome (HUS). Although the STEC O157 serogroup accounts for the highest number of infections, H...

    Authors: Julio A. Guerra, Chengxian Zhang, Jonathan E. Bard, Donald Yergeau, Natasha Halasa and Oscar G. Gómez-Duarte
    Citation: BMC Genomics 2020 21:564
    Content type: Research article Published on:

  49. The ubiquitous presence of short tandem repeats (STRs) in virtually all genomes implicates their functional relevance, while a widely-accepted definition of STR is yet to be established. Previous studies major...

    Authors: Hongxi Zhang, Douyue Li, Xiangyan Zhao, Saichao Pan, Xiaolong Wu, Shan Peng, Hanrou Huang, Ruixue Shi and Zhongyang Tan
    Citation: BMC Genomics 2020 21:563
    Content type: Research article Published on:

  50. Enterohemorrhagic Escherichia coli O157:H7 (EHEC) is a significant foodborne pathogen that resides asymptomatically within cattle and other ruminants. The EHEC genome harbors an extensive collection of mobile gen...

    Authors: Eliot Stanton, Taylor A. Wahlig, Dongjin Park and Charles W. Kaspar
    Citation: BMC Genomics 2020 21:562
    Content type: Research article Published on:

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BMC Genomics

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