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  1. Root hair, a special type of tubular-shaped cell, outgrows from root epidermal cell and plays important roles in the acquisition of nutrients and water, as well as interactions with biotic and abiotic stress. ...

    Authors: Lin Liu, Lu-Guang Jiang, Jin-Hong Luo, Ai-Ai Xia, Li-Qun Chen and Yan He

    Citation: BMC Genomics 2021 22:664

    Content type: Research

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  2. A substantial fraction of genes identified within bacterial genomes encode proteins of unknown function. Identifying which of these proteins represent potential virulence factors, and mapping their key virulen...

    Authors: Briallen Lobb, Benjamin Jean-Marie Tremblay, Gabriel Moreno-Hagelsieb and Andrew C. Doxey

    Citation: BMC Genomics 2021 22:663

    Content type: Research

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  3. Deer mice (genus Peromyscus) are the most common rodents in North America. Despite the availability of reference genomes for some species, a comprehensive database of polymorphisms, especially in those maintained...

    Authors: Matthew D. Lucius, Hao Ji, Diego Altomare, Robert Doran, Ben Torkian, Amanda Havighorst, Vimala Kaza, Youwen Zhang, Alexander V. Gasparian, Joseph Magagnoli, Vijay Shankar, Michael Shtutman and Hippokratis Kiaris

    Citation: BMC Genomics 2021 22:662

    Content type: Research

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  4. Coccidiosis is an infectious disease with large negative impact on the poultry industry worldwide. It is an enteric infection caused by unicellular Apicomplexan parasites of the genus Eimeria. The present study a...

    Authors: Arnar K. S. Sandholt, Eva Wattrang, Tobias Lilja, Harri Ahola, Anna Lundén, Karin Troell, Staffan G. Svärd and Robert Söderlund

    Citation: BMC Genomics 2021 22:660

    Content type: Research

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  5. Zebrafish is a popular animal model used for high-throughput screening of chemical hazards, however, investigations of transcriptomic mechanisms of toxicity are still needed. Here, our goal was to identify gen...

    Authors: Prarthana Shankar, Ryan S. McClure, Katrina M. Waters and Robyn L. Tanguay

    Citation: BMC Genomics 2021 22:658

    Content type: Research

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  6. Authors: Gen Pan, Zheng Li, Siqi Huang, Jie Tao, Yaliang Shi, Anguo Chen, Jianjun Li, Huijuan Tang, Li Chang, Yong Deng, Defang Li and Lining Zhao

    Citation: BMC Genomics 2021 22:657

    Content type: Correction

    Published on:

    The original article was published in BMC Genomics 2021 22:595

  7. Authors: Yao Hu, Stephanie A. Bien, Katherine K. Nishimura, Jeffrey Haessler, Chani J. Hodonsky, Antoine R. Baldassari, Heather M. Highland, Zhe Wang, Michael Preuss, Colleen M. Sitlani, Genevieve L. Wojcik, Ran Tao, Mariaelisa Graff, Laura M. Huckins, Quan Sun, Ming-Huei Chen…

    Citation: BMC Genomics 2021 22:656

    Content type: Correction

    Published on:

    The original article was published in BMC Genomics 2021 22:432

  8. Myxobacteria harbor numerous biosynthetic gene clusters that can produce a diverse range of secondary metabolites. Minicystis rosea DSM 24000T is a soil-dwelling myxobacterium belonging to the suborderSorangiinea...

    Authors: Shilpee Pal, Gaurav Sharma and Srikrishna Subramanian

    Citation: BMC Genomics 2021 22:655

    Content type: Research

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  9. The discovery of male sterile materials is of great significance for the development of plant fertility research. Wucai (Brassica campestris L. ssp. chinensis var. rosularis Tsen) is a variety of non-heading Chin...

    Authors: Jian Wang, Yitao Yang, Lei Zhang, Shaoxing Wang, Lingyun Yuan, Guohu Chen, Xiaoyan Tang, Jinfeng Hou, Shidong Zhu and Chenggang Wang

    Citation: BMC Genomics 2021 22:654

    Content type: Research

    Published on:

  10. As non-coding RNA molecules of more than 200 bp in length, long non-coding RNAs (lncRNAs) play a variety of roles in biological processes, including regulating the immune responses to bacterial infections. In ...

    Authors: Qianhui Sun, Jixiu Wang, Guowen Wang, Huanling Wang and Hong Liu

    Citation: BMC Genomics 2021 22:653

    Content type: Research

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  11. Composting is an important technique for environment-friendly degradation of organic material, and is a microbe-driven process. Previous metagenomic studies of composting have presented a general description o...

    Authors: Lucas Palma Perez Braga, Roberta Verciano Pereira, Layla Farage Martins, Livia Maria Silva Moura, Fabio Beltrame Sanchez, José Salvatore Leister Patané, Aline Maria da Silva and João Carlos Setubal

    Citation: BMC Genomics 2021 22:652

    Content type: Research

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  12. Heterosis has been exploited for decades in different animals and crops due to it resulting in dramatic increases in yield and adaptability. Hybridization is a classical breeding method that can effectively im...

    Authors: Qizhen Xiao, Zekun Huang, Yawei Shen, Yang Gan, Yi Wang, Shihai Gong, Yisha Lu, Xuan Luo, Weiwei You and Caihuan Ke

    Citation: BMC Genomics 2021 22:650

    Content type: Research

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  13. Bacillus cereus is a notorious foodborne pathogen, which can grow under anoxic conditions. Anoxic growth is supported by endogenous redox metabolism, for which the thiol redox proteome serves as an interface. Her...

    Authors: Fella Hamitouche, Jean-Charles Gaillard, Philippe Schmitt, Jean Armengaud, Catherine Duport and Luc Dedieu

    Citation: BMC Genomics 2021 22:648

    Content type: Research

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  14. Agarwood, generated from the Aquilaria sinensis, has high economic and medicinal value. Although its genome has been sequenced, the ploidy of A. sinensis paleopolyploid remains unclear. Moreover, the expression c...

    Authors: Fanbo Meng, Tianzhe Chu, Qiang Tang and Wei Chen

    Citation: BMC Genomics 2021 22:647

    Content type: Research

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  15. Cytoplasmic male sterility (CMS) has been widely used for commercial F1 hybrid seeds production. CMS is primarily caused by chimeric genes in mitochondrial genomes. However, which specific stages of anther dev...

    Authors: Xionghui Zhong, Denghui Chen, Jian Cui, Hailong Li, Yuxin Huang and Jungen Kang

    Citation: BMC Genomics 2021 22:646

    Content type: Research

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  16. Limited access to genetic information has greatly hindered our understanding of the molecular evolution, phylogeny, and differentiation time of subg. Amygdalus. This study reported complete chloroplast (cp) genom...

    Authors: Zhongyu Du, Ke Lu, Kai Zhang, Yiming He, Haitao Wang, Guaiqiang Chai, Jianguo Shi and Yizhong Duan

    Citation: BMC Genomics 2021 22:645

    Content type: Research

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  17. Inversion Symmetry is a generalization of the second Chargaff rule, stating that the count of a string of k nucleotides on a single chromosomal strand equals the count of its inverse (reverse-complement) k-mer...

    Authors: Alon Kafri, Benny Chor and David Horn

    Citation: BMC Genomics 2021 22:644

    Content type: Research

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  18. The lower Dipteran fungus fly, Sciara coprophila, has many unique biological features that challenge the rule of genome DNA constancy. For example, Sciara undergoes paternal chromosome elimination and maternal X ...

    Authors: John M. Urban, Michael S. Foulk, Jacob E. Bliss, C. Michelle Coleman, Nanyan Lu, Reza Mazloom, Susan J. Brown, Allan C. Spradling and Susan A. Gerbi

    Citation: BMC Genomics 2021 22:643

    Content type: Research article

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  19. RNA polymerase II plays critical roles in transcription in eukaryotic organisms. C-terminal Domain Phosphatase-like 1 (CPL1) regulates the phosphorylation state of the C-terminal domain of RNA polymerase II su...

    Authors: Chen Yuan, Jingya Xu, Qianqian Chen, Qinggang Liu, Yikai Hu, Yicheng Jin and Cheng Qin

    Citation: BMC Genomics 2021 22:642

    Content type: Research

    Published on:

  20. Stroke can induce cardiac dysfunction in the absence of primary cardiac disease; however, the mechanisms underlying the interaction between the neurological deficits and the heart are poorly understood. The ob...

    Authors: Jie Chen, Jiahong Gong, Haili Chen, Xuqing Li, Li Wang, Xiaoli Qian, Kecheng Zhou, Ting Wang, Songhe Jiang, Lei Li and Shengcun Li

    Citation: BMC Genomics 2021 22:641

    Content type: Research

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  21. Fatty liver disease prevalently occurs in commercial postpartum dairies, resulting in a worldwide high culling rate because of their subsequent limitations of production and reproduction performance.

    Authors: Letian Zhang, Tingjun Liu, Chengzhang Hu, Xuan Zhang, Qin Zhang and Kerong Shi

    Citation: BMC Genomics 2021 22:640

    Content type: Research

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  22. Resistance of pest insect species to insecticides, including B. thuringiensis (Bt) pesticidal proteins expressed by transgenic plants, is a threat to global food security. Despite the western corn rootworm, Diabr...

    Authors: Brad S. Coates, Emeline Deleury, Aaron J. Gassmann, Bruce E. Hibbard, Lance J. Meinke, Nicholas J. Miller, Jennifer Petzold-Maxwell, B. Wade French, Thomas W. Sappington, Blair D. Siegfried and Thomas Guillemaud

    Citation: BMC Genomics 2021 22:639

    Content type: Research

    Published on:

  23. LncRNAs are extensively involved in plant biological processes. However, the lack of a comprehensive lncRNA landscape in moso bamboo has hindered the molecular study of lncRNAs. Moreover, the role of lncRNAs i...

    Authors: Jiongliang Wang, Yinguang Hou, Yu Wang and Hansheng Zhao

    Citation: BMC Genomics 2021 22:638

    Content type: Research

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  24. The pond snail, Lymnaea stagnalis (L. stagnalis), has served as a valuable model organism for neurobiology studies due to its simple and easily accessible central nervous system (CNS). L. stagnalis has been widel...

    Authors: Martina Rosato, Brittany Hoelscher, Zhenguo Lin, Chidera Agwu and Fenglian Xu

    Citation: BMC Genomics 2021 22:637

    Content type: Research

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  25. Association mapping studies of quantitative trait loci (QTL) for canine hip dysplasia (CHD) can contribute to the understanding of the genetic background of this common and debilitating disease and might contr...

    Authors: Shizhi Wang, Erling Strandberg, Per Arvelius, Dylan N. Clements, Pamela Wiener and Juliane Friedrich

    Citation: BMC Genomics 2021 22:636

    Content type: Research

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  26. Brine shrimp Artemia have an unequalled ability to endure extreme salinity and complete anoxia. This study aims to elucidate its strategies to cope with these stressors.

    Authors: Stephanie De Vos, Stephane Rombauts, Louis Coussement, Wannes Dermauw, Marnik Vuylsteke, Patrick Sorgeloos, James S. Clegg, Ziro Nambu, Filip Van Nieuwerburgh, Parisa Norouzitallab, Thomas Van Leeuwen, Tim De Meyer, Gilbert Van Stappen, Yves Van de Peer and Peter Bossier

    Citation: BMC Genomics 2021 22:635

    Content type: Research

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  27. The gut microbiota provides health benefits in humans by producing short-chain fatty acids (SCFAs), whose deficiency causes multiple disorders and inflammatory diseases. However, gut bacteria producing SCFAs i...

    Authors: Jing Zhang, Kun Zuo, Chen Fang, Xiandong Yin, Xiaoqing Liu, Jiuchang Zhong, Kuibao Li, Jing Li, Li Xu and Xinchun Yang

    Citation: BMC Genomics 2021 22:634

    Content type: Research

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  28. Halogenation is a recurring feature in natural products, especially those from marine organisms. The selectivity with which halogenating enzymes act on their substrates renders halogenases interesting targets ...

    Authors: Nadia Eusebio, Adriana Rego, Nathaniel R. Glasser, Raquel Castelo-Branco, Emily P. Balskus and Pedro N. Leão

    Citation: BMC Genomics 2021 22:633

    Content type: Research

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  29. As an important group of the multidrug efflux transporter family, the multidrug and toxic compound extrusion (MATE) family has a wide range of functions and is distributed in all kingdoms of living organisms. ...

    Authors: Weihan Zhang, Liao Liao, Jinsheng Xu, Yuepeng Han and Li Li

    Citation: BMC Genomics 2021 22:632

    Content type: Research article

    Published on:

  30. There exist few, if any, practical guidelines for predictive and falsifiable multi-omic data integration that systematically integrate existing knowledge. Disease modules are popular concepts for interpreting ...

    Authors: Tejaswi V. S. Badam, Hendrik A. de Weerd, David Martínez-Enguita, Tomas Olsson, Lars Alfredsson, Ingrid Kockum, Maja Jagodic, Zelmina Lubovac-Pilav and Mika Gustafsson

    Citation: BMC Genomics 2021 22:631

    Content type: Research article

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  31. Fusarium culmorum is an important pathogen causing head blight of cereals in Europe. This disease is of worldwide importance leading to reduced yield, grain quality, and contamination by mycotoxins. These mycotox...

    Authors: Thomas Miedaner, Andrea Vasquez, Valheria Castiblanco, Hilda Elena Castillo, Nora Foroud, Tobias Würschum and Willmar Leiser

    Citation: BMC Genomics 2021 22:630

    Content type: Research article

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  32. It is believed that natural selection acts on the phenotypical changes caused by mutations. Phenotypically, from fishes to amphibians to reptiles, the emergence of limbs greatly facilitates the landing of anci...

    Authors: Yankai Jiang, Xinyue Cao and Haibin Wang

    Citation: BMC Genomics 2021 22:629

    Content type: Research article

    Published on:

  33. Streptococcus agalactiae (Group B Streptococcus, GBS) is one of the major bacterial pathogens responsible for neonatal sepsis. Whole genome sequencing has, in recent years, emerged as a reliable tool for capsular...

    Authors: Mienye Bob-Manuel, Lesley McGee, Jeremiah A Igunma, Mary A Alex-Wele, Orikomaba K Obunge and Kennedy T Wariso

    Citation: BMC Genomics 2021 22:627

    Content type: Research

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  34. Long-read sequencing has great promise in enabling portable, rapid molecular-assisted cancer diagnoses. A key challenge in democratizing long-read sequencing technology in the biomedical and clinical community...

    Authors: Shishir Reddy, Ling-Hong Hung, Olga Sala-Torra, Jerald P. Radich, Cecilia CS Yeung and Ka Yee Yeung

    Citation: BMC Genomics 2021 22:626

    Content type: Software

    Published on:

  35. Genome-wide data are invaluable to characterize differentiation and adaptation of natural populations. Reduced representation sequencing (RRS) subsamples a genome repeatedly across many individuals. However, R...

    Authors: Henrik Christiansen, Franz M. Heindler, Bart Hellemans, Quentin Jossart, Francesca Pasotti, Henri Robert, Marie Verheye, Bruno Danis, Marc Kochzius, Frederik Leliaert, Camille Moreau, Tasnim Patel, Anton P. Van de Putte, Ann Vanreusel, Filip A. M. Volckaert and Isa Schön

    Citation: BMC Genomics 2021 22:625

    Content type: Research

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  36. Finding meaningful gene-gene interaction and the main Transcription Factors (TFs) in co-expression networks is one of the most important challenges in gene expression data mining.

    Authors: Carlos Alberto Oliveira de Biagi Jr, Ricardo Perecin Nociti, Danielle Barbosa Brotto, Breno Osvaldo Funicheli, Patrícia de Cássia Ruy, João Paulo Bianchi Ximenez, David Livingstone Alves Figueiredo and Wilson Araújo Silva Jr

    Citation: BMC Genomics 2021 22:624

    Content type: Software

    Published on:

  37. The low cost and rapidity of microsatellite analysis have led to the development of several markers for many species. Because in non-invasive genetics it is recommended to genotype individuals using few loci, ...

    Authors: Erminia Scarpulla, Alessio Boattini, Mario Cozzo, Patrizia Giangregorio, Paolo Ciucci, Nadia Mucci, Ettore Randi and Francesca Davoli

    Citation: BMC Genomics 2021 22:623

    Content type: Methodology article

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  38. Sugarcane (Saccharum) is the most critical sugar crop worldwide. As one of the most enriched transcription factor families in plants, MYB genes display a great potential to contribute to sugarcane improvement by ...

    Authors: Yuan Yuan, Xiping Yang, Mengfan Feng, Hongyan Ding, Muhammad Tahir Khan, Jisen Zhang and Muqing Zhang

    Citation: BMC Genomics 2021 22:622

    Content type: Research

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  39. Grass carp (Ctenopharyngodon idella) is one of the most widely cultivated fishes in China. High stocking density can reportedly affect fish growth and immunity. Herein we performed PacBio long-read single-molecul...

    Authors: Yan He, Hongyan Yu, Honggang Zhao, Hua Zhu, Qingjing Zhang, Anqi Wang, Yubang Shen, Xiaoyan Xu and Jiale Li

    Citation: BMC Genomics 2021 22:620

    Content type: Research

    Published on:

  40. Babesia rossi is a leading cause of morbidity and mortality among the canine population of sub-Saharan Africa, but pathogenesis remains poorly understood. Previous studies of B. rossi infection were derived from ...

    Authors: Rachel L. Smith, Amelia Goddard, Arun Boddapati, Steven Brooks, Johan P. Schoeman, Justin Lack, Andrew Leisewitz and Hans Ackerman

    Citation: BMC Genomics 2021 22:619

    Content type: Research

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  41. Inborn errors of immunity (IEI) are a group of genetic disorders that impair the immune system, with over 400 genes described so far, and hundreds more to be discovered. To facilitate the search for new genes,...

    Authors: Humza A. Khan and Manish J. Butte

    Citation: BMC Genomics 2021 22:618

    Content type: Research

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    The Correction to this article has been published in BMC Genomics 2021 22:745

  42. Chestnut seeds are important kinds of edible nuts rich in starch and protein. The characteristics and nutrient contents of chestnut have been found to show obvious metaxenia effects in previous studies. To imp...

    Authors: Shengxing Li, Zhuogong Shi, Qiurong Zhu, Liang Tao, Wenhui Liang and Zhiheng Zhao

    Citation: BMC Genomics 2021 22:617

    Content type: Research article

    Published on:

  43. The endosymbiont Wolbachia can manipulate arthropod reproduction and invade host populations by inducing cytoplasmic incompatibility (CI). Some host species are coinfected with multiple Wolbachia strains which ma...

    Authors: Jennifer L. Morrow and Markus Riegler

    Citation: BMC Genomics 2021 22:616

    Content type: Research

    Published on:

  44. Disease resilience, which is the ability of an animal to maintain performance under disease, is important for pigs in commercial herds, where they are exposed to various pathogens. Our objective was to investi...

    Authors: Kyu-Sang Lim, Jian Cheng, Austin Putz, Qian Dong, Xuechun Bai, Hamid Beiki, Christopher K. Tuggle, Michael K. Dyck, Pig Gen Canada, Frederic Fortin, John C. S. Harding, Graham S. Plastow and Jack C. M. Dekkers

    Citation: BMC Genomics 2021 22:614

    Content type: Research article

    Published on:

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