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  1. Despite the fact that introns mean an energy and time burden for eukaryotic cells, they play an irreplaceable role in the diversification and regulation of protein production. As a common feature of eukaryotic...

    Authors: Pavel Dvorak, Viktor Hlavac, Vojtech Hanicinec, Bhavana Hemantha Rao and Pavel Soucek
    Citation: BMC Genomics 2024 25:649
  2. Lotus (Nelumbo nucifera G.) is an important aquatic plant with high ornamental, economic, cultural and ecological values, but abiotic stresses seriously affect its growth and distribution. Q-type C2H2 zinc finger...

    Authors: Huan Liu, Yidan Liu, Fangyu Liu, Lihong Zeng, Yingchun Xu, Qijiang Jin and Yanjie Wang
    Citation: BMC Genomics 2024 25:648
  3. At a global scale, the SARS-CoV-2 virus did not remain in its initial genotype for a long period of time, with the first global reports of variants of concern (VOCs) in late 2020. Subsequently, genome sequenci...

    Authors: Alexander Thomas, Thomas Battenfeld, Ivana Kraiselburd, Olympia Anastasiou, Ulf Dittmer, Ann-Kathrin Dörr, Adrian Dörr, Carina Elsner, Jule Gosch, Vu Thuy Khanh Le-Trilling, Simon Magin, René Scholtysik, Pelin Yilmaz, Mirko Trilling, Lara Schöler, Johannes Köster…
    Citation: BMC Genomics 2024 25:647
  4. Ménière's disease (MD) is a disorder of the inner ear that causes episodic bouts of severe dizziness, roaring tinnitus, and fluctuating hearing loss. To date, no targeted therapy exists. As such, we have under...

    Authors: Kathleen M. Fisch, Sara Brin Rosenthal, Adam Mark, Roman Sasik, Chanond A. Nasamran, Royce Clifford, M. Jennifer Derebery, Ely Boussaty, Kristen Jepsen, Jeffrey Harris and Rick A. Friedman
    Citation: BMC Genomics 2024 25:646
  5. Wenchang chickens are one of the most popular local chicken breeds in the Chinese chicken industry. However, the low feed efficiency is the main shortcoming of this breed. Therefore, there is a need to find a ...

    Authors: Keqi Cai, Ranran Liu, Limin Wei, Xiuping Wang, Huanxian Cui, Na Luo, Jie Wen, Yuxiao Chang and Guiping Zhao
    Citation: BMC Genomics 2024 25:645
  6. Faba bean is an important legume crop. The genetic diversity among faba bean genotypes is very important for the genetic improvement of target traits. A set of 128 fab bean genotypes that are originally from E...

    Authors: Ahmed Sallam, Ahmed Amro, Amira M. I. Mourad, Abdallah Rafeek, Andreas Boerner and Shamaseldeen Eltaher
    Citation: BMC Genomics 2024 25:644
  7. The CBM13 family comprises carbohydrate-binding modules that occur mainly in enzymes and in several ricin-B lectins. The ricin-B lectin domain resembles the CBM13 module to a large extent. Historically, ricin-...

    Authors: Tibo De Coninck, Garry P. Gippert, Bernard Henrissat, Tom Desmet and Els J.M. Van Damme
    Citation: BMC Genomics 2024 25:643
  8. Observational studies have preliminarily revealed an association between smoking and gastroesophageal reflux disease (GERD). However, little is known about the causal relationship and shared genetic architectu...

    Authors: Zhaoqi Yan, Yifeng Xu, Keke Li and Liangji Liu
    Citation: BMC Genomics 2024 25:642
  9. The Alpine Merino is a new breed of fine-wool sheep adapted to the cold and arid climate of the plateau in the world. It has been popularized in Northwest China due to its superior adaptability as well as exce...

    Authors: Wentao Zhang, Zengkui Lu, Tingting Guo, Chao Yuan and Jianbin Liu
    Citation: BMC Genomics 2024 25:641
  10. Drought adaptation is critical to many tree species persisting under climate change, however our knowledge of the genetic basis for trees to adapt to drought is limited. This knowledge gap impedes our fundamen...

    Authors: Collin W. Ahrens, Kevin Murray, Richard A. Mazanec, Scott Ferguson, Ashley Jones, David T. Tissue, Margaret Byrne, Justin O. Borevitz and Paul D. Rymer
    Citation: BMC Genomics 2024 25:640
  11. Aging is a prominent risk factor for diverse diseases; therefore, an in-depth understanding of its physiological mechanisms is required. Nonhuman primates, which share the closest genetic relationship with hum...

    Authors: Yunpeng Liu, Shuaiyao Lu, Jing Yang, Yun Yang, Li Jiao, Jingwen Hu, Yanyan Li, Fengmei Yang, Yunli Pang, Yuan Zhao, Yanpan Gao, Wei Liu, Pengcheng Shu, Wei Ge, Zhanlong He and Xiaozhong Peng
    Citation: BMC Genomics 2024 25:639
  12. The breeding of layers emphasizes the continual selection of egg-related traits, such as egg production, egg quality and eggshell, which enhance their productivity and meet the demand of market. As the breedin...

    Authors: Xiaochang Li, Fangren Lan, Xiaoman Chen, Yiyuan Yan, Guangqi Li, Guiqin Wu, Congjiao Sun and Ning Yang
    Citation: BMC Genomics 2024 25:638
  13. Dynamic metabolic reprogramming occurs at different stages of myogenesis and contributes to the fate determination of skeletal muscle satellite cells (MuSCs). Accumulating evidence suggests that mutations in m...

    Authors: Mingming Chen, Yan Li, Xueling Xu, Shuqi Wang, Zhimei Liu, Shiyu Qi, Dandan Si, Zhuo Man, Shoulong Deng, Guoshi Liu, Yue Zhao, Kun Yu and Zhengxing Lian
    Citation: BMC Genomics 2024 25:637
  14. Jasmonate ZIM-domain (JAZ) proteins, which act as negative regulators in the jasmonic acid (JA) signalling pathway, have significant implications for plant development and response to abiotic stress.

    Authors: Wei Yan, Xueming Dong, Rong Li, Xianglong Zhao, Qiang Zhou, Dong Luo and Zhipeng Liu
    Citation: BMC Genomics 2024 25:636
  15. The nervous system is central to coordinating behavioural responses to environmental change, likely including ocean acidification (OA). However, a clear understanding of neurobiological responses to OA is lack...

    Authors: Jodi T. Thomas, Roger Huerlimann, Celia Schunter, Sue-Ann Watson, Philip L. Munday and Timothy Ravasi
    Citation: BMC Genomics 2024 25:635
  16. Previous studies have demonstrated the role of N6-methyladenosine (m6A) RNA methylation in various biological processes, our research is the first to elucidate its specific impact on LCAT mRNA stability and adipo...

    Authors: Xiaohuan Chao, Lijin Guo, Chutian Ye, Aijun Liu, Xiaomeng Wang, Mao Ye, Zhexia Fan, Kang Luan, Jiahao Chen, Chunlei Zhang, Manqing Liu, Bo Zhou, Xiquan Zhang, Zhenhui Li and Qingbin Luo
    Citation: BMC Genomics 2024 25:634
  17. Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder featured by abnormal movements, arising from the extensive neuronal loss and glial dysfunction in the striatum. Although the cause...

    Authors: Mei Liu, Jinlan Zhao, Chengcheng Xue, Jun Yang and Li Ying
    Citation: BMC Genomics 2024 25:633
  18. Although, oocytes from prepubertal donors are known to be less developmentally competent than those from adult donors it does not restrain their ability to produce full-term pregnancies. The transcriptomic pro...

    Authors: Milena Traut, Ilona Kowalczyk-Zieba, Dorota Boruszewska, Joanna Jaworska, Sandra Gąsiorowska, Krzysztof Lukaszuk, Katarzyna Ropka-Molik, Katarzyna Piórkowska, Tomasz Szmatoła and Izabela Woclawek-Potocka
    Citation: BMC Genomics 2024 25:632
  19. Current RNA-seq analysis software for RNA-seq data tends to use similar parameters across different species without considering species-specific differences. However, the suitability and accuracy of these tool...

    Authors: Gao Jiang, Juan-Yu Zheng, Shu-Ning Ren, Weilun Yin, Xinli Xia, Yun Li and Hou-Ling Wang
    Citation: BMC Genomics 2024 25:631
  20. Deep Mutational Scanning (DMS) assays are powerful tools to study sequence-function relationships by measuring the effects of thousands of sequence variants on protein function. During a DMS experiment, severa...

    Authors: Alexandra M Bendel, Kristjana Skendo, Dominique Klein, Kenji Shimada, Kotryna Kauneckaite-Griguole and Guillaume Diss
    Citation: BMC Genomics 2024 25:630
  21. Virome studies on birds, including chickens are relatively scarce, particularly from the African continent. Despite the continuous evolution of RNA viruses and severe losses recorded in poultry from seasonal v...

    Authors: Vivian C. Nwokorogu, Santhosh Pillai, James E. San, Charlene Pillay, Martin M. Nyaga and Saheed Sabiu
    Citation: BMC Genomics 2024 25:629
  22. Modern broiler breeds allow for high feed efficiency and rapid growth, which come at a cost of increased susceptibility to pathogens and disease. Broiler growth rate, feed efficiency, and health are affected b...

    Authors: Paul B. Stege, Dirkjan Schokker, Frank Harders, Soumya K. Kar, Norbert Stockhofe, Vera Perricone, Johanna M. J. Rebel, Ingrid C. de Jong and Alex Bossers
    Citation: BMC Genomics 2024 25:627
  23. Wheat grain endosperm is mainly composed of proteins and starch. The contents and the overall composition of seed storage proteins (SSP) markedly affect the processing quality of wheat flour. Polyploidization ...

    Authors: Qian Hu, Jing Liu, Xiaolei Chen, Carlos Guzmán, Qiang Xu, Yazhou Zhang, Qian Chen, Huaping Tang, Pengfei Qi, Mei Deng, Jian Ma, Guoyue Chen, Yuming Wei, Jirui Wang, Youliang Zheng, Yong Tu…
    Citation: BMC Genomics 2024 25:626
  24. Autophagy is a conserved catabolic process in eukaryotes that contributes to cell survival in response to multiple stresses and is important for organism fitness. Extensive research has shown that autophagy pl...

    Authors: Chenhui Guan, Yalun Li, Qiong Wang, Jiajia Wang, Caijuan Tian, Yuying He and Zhaoxia Li
    Citation: BMC Genomics 2024 25:625
  25. Radish exhibits significant variation in color, particularly in sprouts, leaves, petals, fleshy roots, and other tissues, displaying a range of hues such as green, white, red, purple, and black. Although exten...

    Authors: Yi Liu, Chenchen Wang, Haidong Chen, Guoqiang Dai, Qiushi Cuimu, Wenjie Shen, Liwei Gao, Bo Zhu, Changbin Gao, Lunlin Chen, Daozong Chen, Xueli Zhang and Chen Tan
    Citation: BMC Genomics 2024 25:624
  26. The genotype-by-environment interaction (GxE) in beef cattle can be investigated using reaction norm models to assess environmental sensitivity and, combined with genome-wide association studies (GWAS), to map...

    Authors: Ivan Carvalho Filho, Leonardo M. Arikawa, Lucio F. M. Mota, Gabriel S. Campos, Larissa F. S. Fonseca, Gerardo A. Fernandes Júnior, Flavio S. Schenkel, Daniela Lourenco, Delvan A. Silva, Caio S. Teixeira, Thales L. Silva, Lucia G. Albuquerque and Roberto Carvalheiro
    Citation: BMC Genomics 2024 25:623
  27. Global per capita meat consumption continues to rise, especially pork. Meat quality is influenced by the content of intramuscular fat (IMF) as a key factor. The longissimus dorsi muscle of Dahe pigs (DHM, IMF: 7....

    Authors: Lanlan Yi, Qiuyan Li, Junhong Zhu, Wenjie Cheng, Yuxiao Xie, Ying Huang, Hongye Zhao, Meilin Hao, Hongjiang Wei and Sumei Zhao
    Citation: BMC Genomics 2024 25:622
  28. Whole plant senescence represents the final stage in the life cycle of annual plants, characterized by the decomposition of aging organs and transfer of nutrients to seeds, thereby ensuring the survival of nex...

    Authors: Po-Yi Chen, Thi Thuy Tu Nguyen, Ruey-Hua Lee, Tsai-Wen Hsu, Ming-Hong Kao, Takashi Gojobori, Tzen-Yuh Chiang and Chao-Li Huang
    Citation: BMC Genomics 2024 25:621
  29. Soybean mosaic disease caused by soybean mosaic virus (SMV) is one of the most devastating and widespread diseases in soybean producing areas worldwide. The WRKY transcription factors (TFs) are widely involved in...

    Authors: Zhihua Zhao, Rongna Wang, Weihua Su, Tianjie Sun, Mengnan Qi, Xueyan Zhang, Fengju Wei, Zhouliang Yu, Fuming Xiao, Long Yan, Chunyan Yang, Jie Zhang and Dongmei Wang
    Citation: BMC Genomics 2024 25:620
  30. Plant genomics plays a pivotal role in enhancing global food security and sustainability by offering innovative solutions for improving crop yield, disease resistance, and stress tolerance. As the number of se...

    Authors: Qussai Abbas, Mathias Wilhelm, Bernhard Kuster, Brigitte Poppenberger and Dmitrij Frishman
    Citation: BMC Genomics 2024 25:619
  31. Cyathus olla, belonging to the genus Cyathus within the order Agaricales, is renowned for its bird's nest-like fruiting bodies and has been utilized in folk medicine. However, its genome remains poorly understood...

    Authors: Xiuchao Xie, Ling Zhao, Yu Song, Yanming Qiao, Zhen-Xin Wang and Jianzhao Qi
    Citation: BMC Genomics 2024 25:618
  32. Sika deer (Cervus nippon) holds significance among cervids, with three genomes recently published. However, these genomes still contain hundreds of gaps and display significant discrepancies in continuity and acc...

    Authors: Qianghui Wang, Ruobing Han, Haihua Xing and Heping Li
    Citation: BMC Genomics 2024 25:617
  33. The Drosophila eye has been an important model to understand principles of differentiation, proliferation, apoptosis and tissue morphogenesis. However, a single cell RNA sequence resource that captures gene expre...

    Authors: Komal Kumar Bollepogu Raja, Kelvin Yeung, Yumei Li, Rui Chen and Graeme Mardon
    Citation: BMC Genomics 2024 25:616
  34. Nematodes are the most abundant and diverse metazoans on Earth, and are known to significantly affect ecosystem functioning. A better understanding of their biology and ecology, including potential adaptations...

    Authors: Eli M. S. Gendron, Xue Qing, Joseph L. Sevigny, Hongmei Li, Zhiyin Liu, Mark Blaxter, Thomas O. Powers, W. Kelly Thomas and Dorota L. Porazinska
    Citation: BMC Genomics 2024 25:615
  35. To unravel the evolutionary history of a complex group, a comprehensive reconstruction of its phylogenetic relationships is crucial. This requires meticulous taxon sampling and careful consideration of multipl...

    Authors: Pamela Morales, Felipe Gajardo, Camilo Valdivieso, Moisés A. Valladares, Alex Di Genova, Ariel Orellana, Rodrigo A. Gutiérrez, Mauricio González, Martin Montecino, Alejandro Maass, Marco A. Méndez and Miguel L. Allende
    Citation: BMC Genomics 2024 25:614
  36. The domain of unknown function 247 (DUF247) proteins is involved in plant development and stress response. Rice is an important worldwide cereal crop, although an increasing number of DUF proteins have been id...

    Authors: Feifei Zhang, Yixi Liu, Fang Liu, Jun Yang, Amir Sohail, Chengkai Lu and Peng Xu
    Citation: BMC Genomics 2024 25:613
  37. Salt sensitivity of blood pressure (SSBP) is an intermediate phenotype of hypertension and is a predictor of long-term cardiovascular events and death. However, the genetic structures of SSBP are uncertain, an...

    Authors: Han Qi, Yun-Yi Xie, Xiao-Jun Yang, Juan Xia, Kuo Liu, Feng-Xu Zhang, Wen-Juan Peng, Fu-Yuan Wen, Bing-Xiao Li, Bo-Wen Zhang, Xin-Yue Yao, Bo-Ya Li, Hong-Dao Meng, Zu-Min Shi, Yang Wang and Ling Zhang
    Citation: BMC Genomics 2024 25:612
  38. Ancient northern East Asians (ANEA) from the Yellow River region, who pioneered millet cultivation, play a crucial role in understanding the origins of ethnolinguistically diverse populations in modern China a...

    Authors: Haoran Su, Mengge Wang, Xiangping Li, Shuhan Duan, Qiuxia Sun, Yuntao Sun, Zhiyong Wang, Qingxin Yang, Yuguo Huang, Jie Zhong, Jing Chen, Xiucheng Jiang, Jinyue Ma, Ting Yang, Yunhui Liu, Lintao Luo…
    Citation: BMC Genomics 2024 25:611
  39. Understanding the mechanisms underlying alcohol metabolism and its regulation, including the effect of polymorphisms in alcohol-metabolizing enzymes, is crucial for research on Fetal Alcohol Spectrum Disorders...

    Authors: Melina Vieiros, Elisabet Navarro-Tapia, Anna Ramos-Triguero, Àgueda García-Meseguer, Leopoldo Martínez, Óscar García-Algar and Vicente Andreu-Fernández
    Citation: BMC Genomics 2024 25:610
  40. Adhesins are crucial factors in the virulence of bacterial pathogens such as Escherichia coli. However, to date no resources have been dedicated to the detailed analysis of E. coli adhesins. Here, we provide adhe...

    Authors: Katarzyna Sidorczuk, Michał Burdukiewicz, Klara Cerk, Joachim Fritscher, Robert A. Kingsley, Peter Schierack, Falk Hildebrand and Rafał Kolenda
    Citation: BMC Genomics 2024 25:609
  41. Gastropods of the genus Biomphalaria (Family Planorbidae) are exploited as vectors by Schistosoma mansoni, the most common causative agent of human intestinal schistosomiasis. Using improved genomic resources, ov...

    Authors: Lijun Lu, Lijing Bu, Martina R. Laidemitt, Si-Ming Zhang and Eric S. Loker
    Citation: BMC Genomics 2024 25:608
  42. Chronic Obstructive Pulmonary Disease (COPD) describes a group of progressive lung diseases causing breathing difficulties. While COPD development typically involves a complex interplay between genetic and env...

    Authors: Wei-De Lin, Wen-Ling Liao, Wei-Cheng Chen, Ting-Yuan Liu, Yu-Chia Chen and Fuu-Jen Tsai
    Citation: BMC Genomics 2024 25:607
  43. Gangba sheep as a famous breed of Tibetan sheep, its wool color is mainly white and black. Gangba wool is economically important as a high-quality raw material for Tibetan blankets and Tibetan serge. However, ...

    Authors: Wentao Zhang, Cuicheng Luosang, Chao Yuan, Tingting Guo, Caihong Wei, Jianbin Liu and Zengkui Lu
    Citation: BMC Genomics 2024 25:606
  44. Acer truncatum Bunge is an economic, ecological, oil, and medicinal tree, and its kernel oil is rich in nervonic acid. It is crucial to explore the transcriptional expression patterns of genes affecting fatty aci...

    Authors: Liping Yan, Hongcheng Fang, Yan Liang, Yinhua Wang, Fei Ren, Xiaoman Xie and Dejun Wu
    Citation: BMC Genomics 2024 25:605
  45. Salmonella, an important foodborne pathogen, was estimated to be responsible for 95.1 million cases and 50,771 deaths worldwide. Sixteen serovars were responsible for approximately 80% of Salmonella infections in...

    Authors: Yinfang Shen, Yibin Zhou, Jingyu Gong, Gang Li, Yue Liu, Xuebin Xu and Mingliang Chen
    Citation: BMC Genomics 2024 25:604
  46. Spermatogenesis is a highly regulated and complex process in which DNA methylation plays a crucial role. This study aimed to explore the differential methylation profiles in sperm DNA between patients with ast...

    Authors: Jingdi Zhang, Xiaogang Li, Rongrong Wang, Xinxin Feng, Siyu Wang, Hai Wang, Yutao Wang, Hongjun Li, Yongzhe Li and Ye Guo
    Citation: BMC Genomics 2024 25:602
  47. The herbaceous peony (Paeonia lactiflora Pall.) is extensively cultivated in China due to its root being used as a traditional Chinese medicine known as ‘Radix Paeoniae Alba’. In recent years, it has been discove...

    Authors: Huajie Xu, Miao Li, Di Ma, Jiajun Gao, Jun Tao and Jiasong Meng
    Citation: BMC Genomics 2024 25:601
  48. Splicing variants are a major class of pathogenic mutations, with their severity equivalent to nonsense mutations. However, redundant and degenerate splicing signals hinder functional assessments of sequence v...

    Authors: Ang-Chu Huang, Jia-Ying Su, Yu-Jen Hung, Hung-Lun Chiang, Yi-Ting Chen, Yen-Tsung Huang, Chen-Hsin Albert Yu, Hsin-Nan Lin and Chien-Ling Lin
    Citation: BMC Genomics 2024 25:600

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