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  1. The phytopatogen Claviceps paspali is the causal agent of Ergot disease in Paspalum spp., which includes highly productive forage grasses such as P. dilatatum. This disease impacts dairy and beef production by af...

    Authors: H. Oberti, G. Spangenberg, N. Cogan, R. Reyno, M. Feijoo, S. Murchio and M. Dalla-Rizza

    Citation: BMC Genomics 2021 22:766

    Content type: Research article

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  2. miRNAs regulate circadian patterns by modulating the biological clocks of animals. In our previous study, we found that the clock gene exhibited a cosine expression pattern in the fallopian tube of chicken ute...

    Authors: Zhifu Cui, Zhichao Zhang, Felix Kwame Amevor, Xiaxia Du, Liang Li, Yaofu Tian, Xincheng Kang, Gang Shu, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang and Xiaoling Zhao

    Citation: BMC Genomics 2021 22:764

    Content type: Research

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  3. Mammals have wide variations in testicular position, with scrotal testes in some species and ascrotal testes in others. Although cryptorchidism is hazardous to human health, some mammalian taxa are natural cry...

    Authors: Simin Chai, Xin Huang, Tianzhen Wu, Shixia Xu, Wenhua Ren and Guang Yang

    Citation: BMC Genomics 2021 22:763

    Content type: Research

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  4. Alternative splicing (AS) is an important mechanism of posttranscriptional modification and dynamically regulates multiple physiological processes in plants, including fruit ripening. However, little is known ...

    Authors: Xiaomin Yan, Dan Bai, Hongtao Song, Kui Lin and Erli Pang

    Citation: BMC Genomics 2021 22:762

    Content type: Research

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  5. Xyloglucan endotransglycosylase/hydrolases (XTH) can disrupt and reconnect the xyloglucan chains, modify the cellulose-xyloglucan complex structure in the cell wall to reconstruct the cell wall. Previous studi...

    Authors: Zichen Wu, Chuanlei Cui, Anqi Xing, Xiaohan Xu, Yi Sun, Zhiqiang Tian, Xuyan Li, Jiangyuan Zhu, Genmei Wang and Yuhua Wang

    Citation: BMC Genomics 2021 22:761

    Content type: Research

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  6. Plants grown under shade are exposed to low red/far-red ratio, thereby triggering an array of altered phenotypes called shade avoidance syndrome (SAS). Shade negatively influences plant growth, leading to a re...

    Authors: Nguyen Hoai Nguyen, Benny Jian Rong Sng, Hock Chuan Yeo and In-Cheol Jang

    Citation: BMC Genomics 2021 22:760

    Content type: Research

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  7. Archival formalin-fixed, paraffin-embedded (FFPE) tissue samples with clinical and histological data are a singularly valuable resource for developing new molecular biomarkers. However, transcriptome analysis ...

    Authors: Jin Sung Jang, Eileen Holicky, Julie Lau, Samantha McDonough, Mark Mutawe, Matthew J. Koster, Kenneth J. Warrington and Julie M. Cuninngham

    Citation: BMC Genomics 2021 22:759

    Content type: Methodology article

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  8. Vancomycin-resistant enterococci (VRE) are successful nosocomial pathogens able to cause hospital outbreaks. In the Netherlands, core-genome MLST (cgMLST) based on short-read sequencing is often used for molec...

    Authors: Paola Lisotto, Erwin C. Raangs, Natacha Couto, Sigrid Rosema, Mariëtte Lokate, Xuewei Zhou, Alexander W. Friedrich, John W. A. Rossen, Hermie J. M. Harmsen, Erik Bathoorn and Monika A. Chlebowicz-Fliss

    Citation: BMC Genomics 2021 22:758

    Content type: Research

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  9. The carcass value of cattle is a function of carcass weight and quality. Given the economic importance of carcass merit to producers, it is routinely included in beef breeding objectives. A detailed understand...

    Authors: Pierce Rafter, Isobel Claire Gormley, Deirdre Purfield, Andrew C. Parnell, Saeid Naderi and Donagh P. Berry

    Citation: BMC Genomics 2021 22:757

    Content type: Research

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  10. Much of the complex anatomy of a holometabolous insect is built from disc-shaped epithelial structures found inside the larva, i.e., the imaginal discs, which undergo a rapid differentiation during metamorphos...

    Authors: Michelle Prioli Miranda Soares, Daniel Guariz Pinheiro, Flávia Cristina de Paula Freitas, Zilá Luz Paulino Simões and Márcia Maria Gentile Bitondi

    Citation: BMC Genomics 2021 22:756

    Content type: Research

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  11. Mitochondrial genomes (mitogenomes) have greatly improved our understanding of the backbone phylogeny of Lepidoptera, but few studies on comparative mitogenomics below the family level have been conducted. Her...

    Authors: Mingsheng Yang, Junhao Li, Silin Su, Hongfei Zhang, Zhengbing Wang, Weili Ding and Lili Li

    Citation: BMC Genomics 2021 22:755

    Content type: Research

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  12. Various epigenetic factors are responsible for the non-genetic regulation on gene expression. The epigenetically dysregulated oncogenes or tumor suppressors by miRNA and/or DNA methylation are often observed i...

    Authors: Manu Shivakumar, Seonggyun Han, Younghee Lee and Dokyoon Kim

    Citation: BMC Genomics 2021 22(Suppl 3):754

    Content type: Research

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    This article is part of a Supplement: Volume 22 Supplement 3

  13. Histomonas meleagridis is a protozoan parasite and the causative agent of histomonosis, an important poultry disease whose significance is underlined by the absence of any treatment and prophylaxis. The recent su...

    Authors: Nicola Palmieri, Marcelo de Jesus Ramires, Michael Hess and Ivana Bilic

    Citation: BMC Genomics 2021 22:753

    Content type: Research article

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  14. The outcome of cervical artificial insemination (AI) with frozen-thawed semen in sheep is limited by the inability of sperm to traverse the cervix of some ewe breeds. Previous research has demonstrated that ce...

    Authors: Laura Abril-Parreño, Kieran G. Meade, Anette Kristine Krogenæs, Xavier Druart, Sean Fair and Paul Cormican

    Citation: BMC Genomics 2021 22:752

    Content type: Research

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  15. The transcription of developmental regulatory genes is often controlled by multiple cis-regulatory elements. The identification and functional characterization of distal regulatory elements remains challenging...

    Authors: César Arenas-Mena, Sofija Miljovska, Edward J. Rice, Justin Gurges, Tanvi Shashikant, Zihe Wang, Sevinç Ercan and Charles G. Danko

    Citation: BMC Genomics 2021 22:751

    Content type: Research

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  16. Chloroplast transfer RNAs (tRNAs) can participate in various vital processes. Gymnosperms have important ecological and economic value, and they are the dominant species in forest ecosystems in the Northern He...

    Authors: Yu-He Zhao, Tong Zhou, Jiu-Xia Wang, Yan Li, Min-Feng Fang, Jian-Ni Liu and Zhong-Hu Li

    Citation: BMC Genomics 2021 22:750

    Content type: Research article

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  17. Bovine milk contains extracellular vesicles (EVs) that play a role in cellular communication, acting in either an autocrine, paracrine, or an exocrine manner. The unique properties of the EVs protect the cargo...

    Authors: S. Shome, R. L. Jernigan, D. C. Beitz, S. Clark and E. D. Testroet

    Citation: BMC Genomics 2021 22:749

    Content type: Research

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  18. In recent years, much attention has been given to AP2/ERF transcription factors because they play indispensable roles in many biological processes, such as plant development and biotic and abiotic stress response...

    Authors: Shutao He, Xiaomeng Hao, Shuli He, Xiaoge Hao and Xiaonan Chen

    Citation: BMC Genomics 2021 22:748

    Content type: Research

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  19. Over several decades, a wide range of natural and artificial selection events in response to subtropical environments, intensive pasture and intensive feedlot systems have greatly changed the customary behavio...

    Authors: Dengying Liu, Zhenliang Chen, Wei Zhao, Longyu Guo, Hao Sun, Kai Zhu, Guanglei Liu, Xiuping Shen, Xiaoduo Zhao, Qishan Wang, Peipei Ma and Yuchun Pan

    Citation: BMC Genomics 2021 22:747

    Content type: Research

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  20. Skeletonema species are prominent primary producers, some of which can also cause massive harmful algal blooms (HABs) in coastal waters under specific environmental conditions. Nevertheless, genomic information o...

    Authors: Shuya Liu, Yichao Wang, Qing Xu, Mengjia Zhang and Nansheng Chen

    Citation: BMC Genomics 2021 22:746

    Content type: Research

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  21. Yaks that inhabit the Tibetan Plateau exhibit striking phenotypic and physiological differences from cattle and have adapted well to the extreme conditions on the plateau. However, the mechanisms used by these...

    Authors: Qianyun Ge, Yongbo Guo, Wangshan Zheng, Yuan Cai, Xuebin Qi and Shengguo Zhao

    Citation: BMC Genomics 2021 22:744

    Content type: Research article

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  22. Fruit ripening is an intricate developmental process driven by a highly coordinated action of complex hormonal networks. Ethylene is considered as the main phytohormone that regulates the ripening of climacter...

    Authors: Zahra Iqbal, Mohammed Shariq Iqbal, Lalida Sangpong, Gholamreza Khaksar, Supaart Sirikantaramas and Teerapong Buaboocha

    Citation: BMC Genomics 2021 22:743

    Content type: Research

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  23. Damage to the adult central nervous system often leads to long-term disruptions in function due to the limited capacity for neurological recovery. The central nervous system of the Mediterranean field cricket, Gr...

    Authors: Meera P. Prasad, Donald K. E. Detchou, Felicia Wang, Lisa L. Ledwidge, Sarah E. Kingston and Hadley Wilson Horch

    Citation: BMC Genomics 2021 22:742

    Content type: Research

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  24. Emerging evidence indicates that long noncoding RNAs (lncRNAs) are important regulators of various biological processes, and their expression can be altered following certain pathological conditions, including...

    Authors: Ana C. Ayupe, Felipe Beckedorff, Konstantin Levay, Benito Yon, Yadira Salgueiro, Ramin Shiekhattar and Kevin K. Park

    Citation: BMC Genomics 2021 22:741

    Content type: Research

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  25. Mollusca, a phylum of highly rich species, possess vivid shell colours, but the underlying molecular mechanism remains to be elucidated. DNA methylation, one of the most common epigenetic modifications in euka...

    Authors: Changzi Yuan, Junxia Mao, Hongyan Sun, Yiying Wang, Ming Guo, Xubo Wang, Ying Tian, Zhenlin Hao, Jun Ding and Yaqing Chang

    Citation: BMC Genomics 2021 22:740

    Content type: Research

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  26. Long non-coding RNAs (lncRNAs) play vital roles in many important biological processes in plants. Currently, a large fraction of plant lncRNA studies center at lncRNA identification and functional analysis. On...

    Authors: Shiye Sang, Wen Chen, Di Zhang, Xuan Zhang, Wenjing Yang and Changning Liu

    Citation: BMC Genomics 2021 22(Suppl 3):739

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 22 Supplement 3

  27. Transcription factors, including trihelix transcription factors, play vital roles in various growth and developmental processes and in abiotic stress responses in plants. The trihelix gene has been systematically...

    Authors: Kuiyin Li, Lili Duan, Yubo Zhang, Miaoxiao Shi, Songshu Chen, Mingfang Yang, Yanqing Ding, Yashu Peng, Yabing Dong, Hao Yang, Zhenhua Li, Liyi Zhang, Yu Fan and Mingjian Ren

    Citation: BMC Genomics 2021 22:738

    Content type: Research

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  28. The detection of signatures of selection in genomic regions provides insights into the evolutionary process, enabling discoveries regarding complex phenotypic traits. In this research, we focused on identifyin...

    Authors: Wellington B. Santos, Gustavo P. Schettini, Amanda M. Maiorano, Fernando O. Bussiman, Júlio C. C. Balieiro, Guilherme C. Ferraz, Guilherme L. Pereira, Welder Angelo Baldassini, Otávio R. M. Neto, Henrique N. Oliveira and Rogério A. Curi

    Citation: BMC Genomics 2021 22:737

    Content type: Research

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  29. Numerous Ebola virus outbreaks have occurred in Equatorial Africa over the past decades. Besides human fatalities, gorillas and chimpanzees have also succumbed to the fatal virus. The 2004 outbreak at the Odza...

    Authors: Claudia Fontsere, Peter Frandsen, Jessica Hernandez-Rodriguez, Jonas Niemann, Camilla Hjorth Scharff-Olsen, Dominique Vallet, Pascaline Le Gouar, Nelly Ménard, Arcadi Navarro, Hans R. Siegismund, Christina Hvilsom, M. Thomas P. Gilbert, Martin Kuhlwilm, David Hughes and Tomas Marques-Bonet

    Citation: BMC Genomics 2021 22:735

    Content type: Research

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  30. The fungal pathogen Fusarium oxysporum f.sp. pisi (Fop) causes Fusarium wilt in peas. There are four races globally: 1, 2, 5 and 6 and all of these races are present in Australia. Molecular infection mechanisms h...

    Authors: Saidi R. Achari, Jacqueline Edwards, Ross C. Mann, Jatinder K. Kaur, Tim Sawbridge and Brett A. Summerell

    Citation: BMC Genomics 2021 22:734

    Content type: Research article

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  31. Functional genome annotation is the process of labelling functional genomic regions with descriptive information. Manual curation can produce higher quality genome annotations than fully automated methods. Man...

    Authors: Matthew R. Lueder, Regina Z. Cer, Miles Patrick, Logan J. Voegtly, Kyle A. Long, Gregory K. Rice and Kimberly A. Bishop-Lilly

    Citation: BMC Genomics 2021 22:733

    Content type: Software

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  32. Enzyme-based host depletion significantly improves the sensitivity of clinical metagenomics. Recent studies found that real-time adaptive sequencing of DNA molecules was achieved using a nanopore sequencing ma...

    Authors: Mingyu Gan, Bingbing Wu, Gangfeng Yan, Gang Li, Li Sun, Guoping Lu and Wenhao Zhou

    Citation: BMC Genomics 2021 22:732

    Content type: Research article

    Published on:

  33. Trees such as Populus are planted extensively for reforestation and afforestation. However, their successful establishment greatly depends upon ambient environmental conditions and their relative resistance to ab...

    Authors: Fang He, Yu-Jie Shi, Qian Zhao, Kuang-Ji Zhao, Xing-Lei Cui, Liang-Hua Chen, Han-Bo Yang, Fan Zhang, Jia-Xuan Mi, Jin-Liang Huang and Xue-Qin Wan

    Citation: BMC Genomics 2021 22:731

    Content type: Research

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  34. Understanding the genetic structure and local adaptive evolutionary mechanisms of marine organisms is crucial for the management of biological resources. As the ecologically and commercially important small-si...

    Authors: Linlin Zhao, Fangyuan Qu, Na Song, Zhiqiang Han, Tianxiang Gao and Zhaohui Zhang

    Citation: BMC Genomics 2021 22:729

    Content type: Research

    Published on:

  35. The seminal vesicles synthesise bioactive factors that support gamete function, modulate the female reproductive tract to promote implantation, and influence developmental programming of offspring phenotype. D...

    Authors: David A. Skerrett-Byrne, Brett Nixon, Elizabeth G. Bromfield, James Breen, Natalie A. Trigg, Simone J. Stanger, Ilana R. Bernstein, Amanda L. Anderson, Tessa Lord, R. John Aitken, Shaun D. Roman, Sarah A. Robertson and John E. Schjenken

    Citation: BMC Genomics 2021 22:728

    Content type: Research

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  36. CONSTANS-like (CO-like, COL) are putative zinc-finger transcription factors known to play vital role in various plant biological processes such as control of flowering time, regulation of plant growth and deve...

    Authors: Khadiza Khatun, Sourav Debnath, Arif Hasan Khan Robin, Antt Htet Wai, Ujjal Kumar Nath, Do-Jin Lee, Chang-Kil Kim and Mi-Young Chung

    Citation: BMC Genomics 2021 22:727

    Content type: Research

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  37. The golden lion tamarin (Leontopithecus rosalia) is an endangered Platyrrhine primate endemic to the Atlantic coastal forests of Brazil. Despite ongoing conservation efforts, genetic data on this species remains ...

    Authors: Nicole Wanner, Peter A. Larsen, Adam McLain and Christopher Faulk

    Citation: BMC Genomics 2021 22:726

    Content type: Research

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  38. Areca palm (Areca catechu L.) is an important commercial crop in southeast Asia, but its cultivation is threatened by yellowing leaf disease (YLD). Areca palm velarivirus 1 (APV1) was recently associated with YLD...

    Authors: Xianmei Cao, Ruibai Zhao, Hongxing Wang, Huaiwen Zhang, Xue Zhao, Latif Ullah Khan and Xi Huang

    Citation: BMC Genomics 2021 22:725

    Content type: Research

    Published on:

  39. Many studies on long chain non-coding RNAs (lncRNAs) are published in recent years. But the roles of lncRNAs in aortic dissection (AD) are still unclear and should be further examined. The present work focused...

    Authors: Hao Zhang, Ce Bian, Simei Tu, Fanxing Yin, Panpan Guo, Jian Zhang, Xiaotong Song, Qingyang Liu, Chen Chen and Yanshuo Han

    Citation: BMC Genomics 2021 22:724

    Content type: Research

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  40. White lupin (Lupinus albus) is a leguminous crop with elite adaptive ability in phosphorus-deficient soil and used as a model plant for studying phosphorus (P) use. However, the genetic basis of its adaptation to...

    Authors: Mehtab Muhammad Aslam, Muhammad Waseem, Qian Zhang, Wang Ke, Jianhua Zhang and Weifeng Xu

    Citation: BMC Genomics 2021 22:723

    Content type: Research

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  41. Glioma is the most common central nervous system tumor with a poor survival rate and prognosis. Previous studies have found that long non-coding RNA (lncRNA) and competitive endogenous RNA (ceRNA) play importa...

    Authors: Guangdong Liu, Haihong Li, Wenyang Ji, Haidong Gong, Yan Jiang, Guomin Ji and Guangyao Liu

    Citation: BMC Genomics 2021 22:722

    Content type: Research

    Published on:

  42. The American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen) presented technical standards for interpretation and reporting of constitutional copy-number variants in ...

    Authors: Chunna Fan, Zhonghua Wang, Yan Sun, Jun Sun, Xi Liu, Licheng Kang, Yingshuo Xu, Manqiu Yang, Wentao Dai, Lijie Song, Xiaoming Wei, Jiale Xiang, Hui Huang, Meizhen Zhou, Fanwei Zeng, Lin Huang…

    Citation: BMC Genomics 2021 22:721

    Content type: Research

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  43. Varroa destructor mites, and the numerous viruses they vector to their honey bee hosts, are among the most serious threats to honey bee populations, causing mortality and morbidity to both the individual honey be...

    Authors: Daniel B. Weaver, Brandi L. Cantarel, Christine G. Elsik, Dawn L. Boncristiani and Jay D. Evans

    Citation: BMC Genomics 2021 22:720

    Content type: Research

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  44. Despite increasing interest in γδ T cells and their non-classical behaviour, most studies focus on animals with low numbers of circulating γδ T cells, such as mice and humans. Arguably, γδ T cell functions mig...

    Authors: Robert Dixon, Stephen G. Preston, Stefan Dascalu, Patrik G. Flammer, Steven R. Fiddaman, Kirstie McLoughlin, Amy Boyd, Jiri Volf, Ivan Rychlik, Michael B. Bonsall, Bernd Kaspers and Adrian L. Smith

    Citation: BMC Genomics 2021 22:719

    Content type: Research

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  45. Overlapping genes share same genomic regions in parallel (sense) or anti-parallel (anti-sense) orientations. These gene pairs seem to occur in all domains of life and are best known from viruses. However, the ...

    Authors: Majid Mehravar, Fatemeh Ghaemimanesh and Ensieh M. Poursani

    Citation: BMC Genomics 2021 22:718

    Content type: Research

    Published on:

  46. In recent years, animal welfare and health has become more and more important in pig breeding. So far, numerous parameters have been considered as important biomarkers, especially in the immune reaction and in...

    Authors: Christina M. Dauben, Maren J. Pröll-Cornelissen, Esther M. Heuß, Anne K. Appel, Hubert Henne, Katharina Roth, Karl Schellander, Ernst Tholen and Christine Große-Brinkhaus

    Citation: BMC Genomics 2021 22:717

    Content type: Research

    Published on:

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