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  1. We previously reported a familial thyroid follicular cell carcinoma (FCC) in a large number of Dutch German longhaired pointers and identified two deleterious germline mutations in the TPO gene associated with di...

    Authors: Yun Yu, Freek Manders, Guy C. M. Grinwis, Martien A. M. Groenen and Richard P. M. A. Crooijmans
    Citation: BMC Genomics 2022 23:669
    Content type: Research Published on:

  2. Many endangered species exist in small, genetically depauperate, or inbred populations, hence promoting genetic differentiation and reducing long-term population viability. Forest Musk Deer (Moschus berezovskii) ...

    Authors: Gang Liu, Bao-Feng Zhang, Jiang Chang, Xiao-Long Hu, Chao Li, Tin-Tao Xu, Shu-Qiang Liu and De-Fu Hu
    Citation: BMC Genomics 2022 23:668
    Content type: Research Published on:

  3. As a type of calmodulin binding protein, CAMTAs are widely involved in vegetative and reproductive processes as well as various hormonal and stress responses in plants. To study the functions of CAMTA genes in te...

    Authors: Bo Li, Shan He, Yiqian Zheng, Yu Wang, Xuxu Lang, Huan Wang, Kai Fan, Jianhui Hu, Zhaotang Ding and Wenjun Qian
    Citation: BMC Genomics 2022 23:667
    Content type: Research Published on:

  4. Severe peripheral nerve injury leads to the irreparable disruption of nerve fibers. This leads to disruption of synapses with the designated muscle, which consequently go through progressive atrophy and damage...

    Authors: Haotao Li, Wanqiong Yuan, Yijian Chen, Bofu Lin, Shuai Wang, Zhantao Deng, Qiujian Zheng and Qingtian Li
    Citation: BMC Genomics 2022 23:666
    Content type: Research Published on:

  5. Portal vein ligation (PVL)-induced liver hypertrophy increases future liver remnant (FLR) volume and improves resectability of large hepatic carcinoma. However, the molecular mechanism by which PVL facilitates...

    Authors: Yan Zhu, Zhishuai Li, Jixiang Zhang, Mingqi Liu, Xiaoqing Jiang and Bin Li
    Citation: BMC Genomics 2022 23:665
    Content type: Research Published on:

  7. There is a need to match characteristics of tobacco users with cessation treatments and risks of tobacco attributable diseases such as lung cancer. The rate in which the body metabolizes nicotine has proven an...

    Authors: James W. Baurley, Andrew W. Bergen, Carolyn M. Ervin, Sung-shim Lani Park, Sharon E. Murphy and Christopher S. McMahan
    Citation: BMC Genomics 2022 23:663
    Content type: Research Published on:

  8. P-selectin is a molecule participating in the inflammatory response through mediating cellular adhesion and essential for wound repair. However, studies regarding P-selectin in Bivalvia are rare. This study id...

    Authors: Yuanfeng Xu, Xumeng Dong, Shuonan Ma, Cheng Luo and Jilin Xu
    Citation: BMC Genomics 2022 23:662
    Content type: Research Published on:

  9. To identify operational taxonomy units (OTUs) signaling disease onset in an observational study, a powerful strategy was selecting participants by matched sets and profiling temporal metagenomes, followed by t...

    Authors: Qian Li, Kendra Vehik, Cai Li, Eric Triplett, Luiz Roesch, Yi-Juan Hu and Jeffrey Krischer
    Citation: BMC Genomics 2022 23:661
    Content type: Research Published on:

  10. Brown adipose tissue (BAT) is considered as a primary location of adaptive thermogenesis and the thermogenic activities of brown adipocytes are also connected to generating heat and counteracting obesity. Rece...

    Authors: Pengyu Hong, Yue Wu, Qi Zhang, Pan Liu, Siyuan Zhang, Mei Yu and Weidong Tian
    Citation: BMC Genomics 2022 23:660
    Content type: Research Published on:

  11. Segmented filamentous bacteria (SFB) are intestinal commensal microorganisms that have been demonstrated to induce the innate and adaptive immune responses in mouse and rat hosts. SFB are Gram-positive, spore-...

    Authors: Grant A. Hedblom, Kamal Dev, Steven D. Bowden and David J. Baumler
    Citation: BMC Genomics 2022 23:659
    Content type: Research Published on:

  12. LncRNAs are tissue-specific and emerge as important regulators of various biological processes and as disease biomarkers. HOTAIR is a well-established pro-oncogenic lncRNA which has been attributed a variety of f...

    Authors: Evdokiia Potolitsyna, Sarah Hazell Pickering, Ave Tooming-Klunderud, Philippe Collas and Nolwenn Briand
    Citation: BMC Genomics 2022 23:658
    Content type: Research Published on:

  13. Titinopathies are inherited muscular diseases triggered by genetic mutations in the titin gene. Muscular dystrophy with myositis (mdm) is one such disease caused by a LINE repeat insertion, leading to exon skippi...

    Authors: Pabodha Hettige, Uzma Tahir, Kiisa C. Nishikawa and Matthew J. Gage
    Citation: BMC Genomics 2022 23:657
    Content type: Research Published on:

  14. General transcription factor IIi (GTF2I) mutations are very common in thymic epithelial tumors (TETs) and are related to a more favorable prognosis in TET patients. However, limited research has been conducted...

    Authors: Wei Liu, Hao-Shuai Yang, Shao-Yi Zheng, Jian-Hao Weng, Hong-He Luo, Yi-Yan Lei and Yan-Fen Feng
    Citation: BMC Genomics 2022 23:656
    Content type: Research Published on:

  18. Multiprotein bridging factor 1 (MBF1) is a crucial transcriptional coactivator in animals, plants, and some microorganisms, that plays a necessary role in growth development and stress tolerance. Zanthoxylum arma...

    Authors: Wenkai Hui, Hao Zheng, Jiangtao Fan, Jingyan Wang, Tahseen Saba, Kai Wang, Jiaojiao Wu, Han Wu, Yu Zhong, Gang Chen and Wei Gong
    Citation: BMC Genomics 2022 23:652
    Content type: Research Published on:

  19. Alfalfa (Medicago sativa) is a widely cultivated plant. Unlike many crops, the main goal of breeding alfalfa is to increase its aboveground biomass rather than the biomass of its seeds. However, the low yield of ...

    Authors: Lu Zhao, Mingyu Li, Xiaomei Ma, Dong Luo, Qiang Zhou, Wenxian Liu and Zhipeng Liu
    Citation: BMC Genomics 2022 23:651
    Content type: Research Published on:

  20. As one of the largest transcription factor families in plants, AP2/ERF gene superfamily plays important roles in plant growth, development, fruit ripening and biotic and abiotic stress responses. Despite the grea...

    Authors: Quan Jiang, Zhi Wang, Guangming Hu and Xiaohong Yao
    Citation: BMC Genomics 2022 23:650
    Content type: Research Published on:

  21. Copy number variations (CNVs) represent a major source of genetic diversity and contribute to the phenotypic variation of economically important traits in livestock species. In this study, we report the first ...

    Authors: Pourya Davoudi, Duy Ngoc Do, Bruce Rathgeber, Stefanie M. Colombo, Mehdi Sargolzaei, Graham Plastow, Zhiquan Wang, Karim Karimi, Guoyu Hu, Shafagh Valipour and Younes Miar
    Citation: BMC Genomics 2022 23:649
    Content type: Research Published on:

  22. Crops face several environmental stresses (biotic and abiotic), thus resulting in severe yield losses. Around the globe abiotic stresses are the main contributors of plant damages, primarily drought and salini...

    Authors: Teame Gereziher Mehari, Yuqing Hou, Yanchao Xu, Muhammad Jawad Umer, Margaret Linyerera Shiraku, Yuhong Wang, Heng Wang, Renhai Peng, Yangyang Wei, Xiaoyan Cai, Zhongli Zhou and Fang Liu
    Citation: BMC Genomics 2022 23:648
    Content type: Research Published on:

  23. Cynomolgus macaque (Macaca fascicularis) is an attractive animal model for the study of human disease and is extensively used in biomedical research. Cynomolgus macaques share behavioral, physiological, and genom...

    Authors: Swati Jaiswal, Sarah K. Nyquist, Shayla Boyce, Tasneem Jivanjee, Samira Ibrahim, Joshua D. Bromley, G. James Gatter, Hannah Gideon, Kush Patel, Sharie Keanne Ganchua, Bonnie Berger, Sarah M. Fortune, JoAnne L. Flynn, Alex K. Shalek and Samuel M. Behar
    Citation: BMC Genomics 2022 23:647
    Content type: Research Published on:

  24. Heat Shock Proteins 70 (HSP70s) in insects act on a diverse range of substrates to assist with overcoming extreme high temperatures. MaltHSP70-2, a member of HSP70s, has been characterized to involve in the th...

    Authors: Hui Li, Shouyin Li, Jin Chen, Lulu Dai, Ruixu Chen, Jianren Ye and Dejun Hao
    Citation: BMC Genomics 2022 23:646
    Content type: Research Published on:

  25. To date, whole genome sequencing has been performed mainly for isolates of Chlamydia trachomatis, C. pneumoniae, C. psittaci and C. abortus, but only a few isolates of C. pecorum have been entirely sequenced and ...

    Authors: Sara Rigamonti, Anna Maria Floriano, Erika Scaltriti, David Longbottom, Morag Livingstone, Francesco Comandatore, Stefano Pongolini, Lorenzo Capucci, Maria Lucia Mandola, Moira Bazzucchi, Paola Prati and Nadia Vicari
    Citation: BMC Genomics 2022 23:645
    Content type: Research Published on:

  26. Donkey meat has low fat and high protein contents and is rich in various unsaturated fatty acids and trace elements that are beneficial to human digestion and absorption. IMF (intramuscular fat), also known as...

    Authors: Wufeng Li, Lixia Qiu, Jiawei Guan, Yutong Sun, Jingwei Zhao and Min Du
    Citation: BMC Genomics 2022 23:644
    Content type: Research Published on:

  27. Ferula L. is one of the largest and most taxonomically complicated genera as well as being an important medicinal plant resource in the family Apiaceae. To investigate the plastome features and phylogenetic relat...

    Authors: Lei Yang, Ozodbek Abduraimov, Komiljon Tojibaev, Khabibullo Shomurodov, Yuan-Ming Zhang and Wen-Jun Li
    Citation: BMC Genomics 2022 23:643
    Content type: Research Published on:

  29. Maternal gene products supplied to the egg during oogenesis drive the earliest events of development in all metazoans. After the initial stages of embryogenesis, maternal transcripts are degraded as zygotic tr...

    Authors: Anna A. Feitzinger, Anthony Le, Ammon Thompson, Mehnoor Haseeb, Mohan Koumar Murugesan, Austin M. Tang and Susan E. Lott
    Citation: BMC Genomics 2022 23:641
    Content type: Research article Published on:

  30. Walnut is an important economic tree species while confronting with global environmental stress, resulting in decline in quality and yield. Therefore, it is urgent to elucidate the molecular mechanism for the ...

    Authors: Chen Sisi, Deng Jieru, Cheng Peidong, Zhang Zhaolong, Wang Yihang, Chen Shuwen, Tang Yan, Wang Tianyu and Yang Guiyan
    Citation: BMC Genomics 2022 23:640
    Content type: Research Published on:

  31. Sinosenecio B. Nordenstam (Asteraceae) currently comprises 44 species. To investigate the interspecific relationship, several chloroplast markers, including ndhC-trnV, rpl32-trnL, matK, and rbcL, are used to anal...

    Authors: Jing-Yi Peng, Xiao-Shuang Zhang, Dai-Gui Zhang, Yi Wang, Tao Deng, Xian-Han Huang, Tian-Hui Kuang and Qiang Zhou
    Citation: BMC Genomics 2022 23:639
    Content type: Research Published on:

  32. The strawberry fleshy fruit is actually enlarged receptacle tissue, and the successful development of the embryo and endosperm is essential for receptacle fruit set. MicroRNAs (miRNAs) and phased small interfe...

    Authors: Xiaotong Jing, Hong Zhang, Xinjia Huai, Qi An and Yushan Qiao
    Citation: BMC Genomics 2022 23:638
    Content type: Research Published on:

  33. The coevolutionary dynamics of corresponding male and female sexual traits, including genitalia, may be driven by complex genetic mechanisms. Carabus (Ohomopterus) ground beetles show correlated evolution in the ...

    Authors: Shota Nomura and Teiji Sota
    Citation: BMC Genomics 2022 23:637
    Content type: Research Published on:

  35. Tandem mass tag spectrometry (TMT labeling-LC-MS/MS) was utilized to examine the global proteomes of Atlantic halibut eggs at the 1-cell-stage post fertilization. Comparisons were made between eggs judged to b...

    Authors: Ozlem Yilmaz, Anders Mangor Jensen, Torstein Harboe, Margareth Møgster, Ragnfrid Mangor Jensen, Olav Mjaavatten, Even Birkeland, Endy Spriet, Linda Sandven, Tomasz Furmanek, Frode S. Berven, Anna Wargelius and Birgitta Norberg
    Citation: BMC Genomics 2022 23:635
    Content type: Research article Published on:

  36. 9-cis-epoxycarotenoid dioxygenase (NCED) is the rate-limiting enzyme for abscisic acid (ABA) biosynthesis in higher plants. In rice, OsNCED3 was shown to promote ABA synthesis, and improve abiotic stress toleranc...

    Authors: Litong Sun, Jitong Li, Yongyan Liu, Ali Noman, Lin Chen and Jinglan Liu
    Citation: BMC Genomics 2022 23:634
    Content type: Research Published on:

  37. Growing oocytes acquire the ability to mature through two-way communication between gametes and surrounding somatic cumulus cells (CCs). Granulosa cells (GCs) support oocyte growth, regulate meiosis progressio...

    Authors: Ling Zhao, Yangyang Pan, Meng Wang, Junqian Wang, Yaying Wang, Xiaohong Han, Jinglei Wang, Tongxiang Zhang, Tian Zhao, Honghong He, Yan Cui and Sijiu Yu
    Citation: BMC Genomics 2022 23:633
    Content type: Research Published on:

  38. Gummy stem blight (GSB), caused by Didymella bryoniae (syn. Stagonosporopsis cucurbitacearum), produces devastating symptoms on whole plants of watermelon (Citrullus lanatus) and other cucurbits, significantly re...

    Authors: Jeong-Eui Hong, Mohammad Rashed Hossain, Hee-Jeong Jung and Ill-Sup Nou
    Citation: BMC Genomics 2022 23:632
    Content type: Research Published on:

  39. Structural variants and tandem repeats are relevant sources of genomic variation that are not routinely analyzed in genome wide association studies mainly due to challenging identification and genotyping. Here...

    Authors: Iulia Blaj, Jens Tetens, Jörn Bennewitz, Georg Thaller and Clemens Falker-Gieske
    Citation: BMC Genomics 2022 23:631
    Content type: Research Published on:

  40. Thyroid-associated ophthalmopathy (TAO) is a common and organ-specific autoimmune disease. Early diagnosis and novel treatments are essential to improve the prognosis of TAO patients. Therefore, the current wo...

    Authors: Yueyue Wang, Yanfei Shao, Haitao Zhang, Jun Wang, Peng Zhang, Weizhong Zhang and Huanhuan Chen
    Citation: BMC Genomics 2022 23:630
    Content type: Research Published on:

  41. Sargassum polycystum C. Agardh and Sargassum plagiophyllum C. Agardh are inhabitants of tropical coastal areas, their populations are negatively influenced by global warming and marine environment changes. The mi...

    Authors: Shuangshuang Zhang, Yanshuo Liang, Jie Zhang, Stefano G. A. Draisma and Delin Duan
    Citation: BMC Genomics 2022 23:629
    Content type: Research Published on:

  42. Spliceosomal introns are parts of primary transcripts that are removed by RNA splicing. Although introns apparently do not contribute to the function of the mature transcript, in vertebrates they comprise the ...

    Authors: Lars Martin Jakt, Arseny Dubin and Steinar Daae Johansen
    Citation: BMC Genomics 2022 23:628
    Content type: Research article Published on:

  43. Genomic surveillance and identification of COVID-19 outbreaks are important in understanding the genetic diversity, phylogeny, and lineages of SARS-CoV-2. Genomic surveillance provides insights into circulatin...

    Authors: Josiah O. Kuja, Bernard N. Kanoi, Renzo F. Balboa, Clement Shiluli, Michael Maina, Harrison Waweru, Kimita Gathii, Mary Mungai, Moses Masika, Omu Anzala, Matilu Mwau, Taane G. Clark, John Waitumbi and Jesse Gitaka
    Citation: BMC Genomics 2022 23:627
    Content type: Research Published on:

  44. Balanites aegyptiaca (L.) Delile, commonly known as desert date, is a thorny evergreen tree belonging to the family Zygophyllaceae and subfamily Tribuloideae that is widespread in arid and semiarid regions. This...

    Authors: Widad S. AL-Juhani, Samah A. Alharbi, Nora M. Al Aboud and Ashwaq Y. Aljohani
    Citation: BMC Genomics 2022 23:626
    Content type: Research Published on:

  45. Macrobrachium nipponense is an economically and ecologically important freshwater prawn that is widely farmed in China. In contrast to other species of marine shrimp, M. nipponense has a short sexual maturity per...

    Authors: Sufei Jiang, Wenyi Zhang, Yiwei Xiong, Dan Cheng, Jisheng Wang, Shubo Jin, Yongsheng Gong, Yan Wu, Hui Qiao and Hongtuo Fu
    Citation: BMC Genomics 2022 23:625
    Content type: Research Published on:

  46. Selection of optimal computational strategies for analyzing metagenomics data is a decisive step in determining the microbial composition of a sample, and this procedure is complex because of the numerous tool...

    Authors: Carine Poussin, Lusine Khachatryan, Nicolas Sierro, Vijay Kumar Narsapuram, Fernando Meyer, Vinay Kaikala, Vandna Chawla, Usha Muppirala, Sunil Kumar, Vincenzo Belcastro, James N. D. Battey, Elena Scotti, Stéphanie Boué, Alice C. McHardy, Manuel C. Peitsch, Nikolai V. Ivanov…
    Citation: BMC Genomics 2022 23:624
    Content type: Research Published on:

  47. The pathophysiological effects of a number of metabolic and age-related disorders can be prevented to some extent by exercise and increased physical activity. However, the molecular mechanisms that contribute ...

    Authors: Arpan C. Ghosh, Yanhui Hu, Sudhir Gopal Tattikota, Yifang Liu, Aram Comjean and Norbert Perrimon
    Citation: BMC Genomics 2022 23:623
    Content type: Research Published on:

  48. Equid gammaherpesvirus 2 (EHV2) is a gammaherpesvirus with a widespread distribution in horse populations globally. Although its pathogenic significance can be unclear in most cases of infection, EHV2 infectio...

    Authors: Adepeju E. Onasanya, Charles El-Hage, Andrés Diaz-Méndez, Paola K. Vaz, Alistair R. Legione, Glenn F. Browning, Joanne M. Devlin and Carol A. Hartley
    Citation: BMC Genomics 2022 23:622
    Content type: Research Published on:

  49. Lysine 2-hydroxyisobutyrylation (Khib) is a novel and conserved post-translational modification (PTM). Frankliniella occidentalis are economically important agricultural pests globally and also notorious for vect...

    Authors: Chengying Ding, Liyun Song, Ying Li, Lili Shen, Dongyang Liu, Fenglong Wang, Zhonglong Lin and Jinguang Yang
    Citation: BMC Genomics 2022 23:621
    Content type: Research Published on:

  50. The objective of this study was to reveal the flavonoid biosynthesis pathway in white (Z6), red (Z27) and black (HC4) seeds of the sweet sorghum (Sorghum bicolor) using metabolomics and transcriptomics, to identi...

    Authors: Yaxing Zhou, Jingbo Lv, Zhonghao Yu, Zhenguo Wang, Yan Li, Mo Li, Zhilan Deng, Qingquan Xu, Fengjuan Cui and Wei Zhou
    Citation: BMC Genomics 2022 23:619
    Content type: Research Published on:

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BMC Genomics

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