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  1. Content type: Research article

    Lung cancer is a major cause of cancer-related mortality worldwide, and around two-thirds of patients have metastasis at diagnosis. Thus, detecting lung cancer at an early stage could reduce mortality. Aberran...

    Authors: Yuhong Dou, Yong Zhu, Junmei Ai, Hankui Chen, Helu Liu, Jeffrey A. Borgia, Xiao Li, Fan Yang, Bin Jiang, Jun Wang and Youping Deng

    Citation: BMC Genomics 2018 19:545

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  2. Content type: Research article

    Since the proposal of Brachypodium distachyon as a model for the grasses, over 500 Bdi-miRNAs have been annotated in miRBase making Brachypodium second in number only to rice. Other monocots, such as switchgrass,...

    Authors: Karl R. Franke, Skye A. Schmidt, Sunhee Park, Dong-Hoon Jeong, Monica Accerbi and Pamela J. Green

    Citation: BMC Genomics 2018 19:547

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  3. Content type: Research article

    The peach fruit moth, Carposina sasakii Matsumura (Lepidoptera: Carposinidae), poses a serious threat to a variety of fruits and causes significant economic loss owing to difficulties in its prevention and contro...

    Authors: Zhiqiang Tian, Lina Sun, Yanyan Li, Linfa Quan, Huaijiang Zhang, Wentao Yan, Qiang Yue and Guisheng Qiu

    Citation: BMC Genomics 2018 19:544

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  4. Content type: Research article

    Thraustochytrids are unicellular fungal-like marine protists with ubiquitous existence in marine environments. They are well-known for their ability to produce high-valued omega-3 polyunsaturated fatty acids (...

    Authors: Zhiquan Song, Jason E. Stajich, Yunxuan Xie, Xianhua Liu, Yaodong He, Jinfeng Chen, Glenn R. Hicks and Guangyi Wang

    Citation: BMC Genomics 2018 19:541

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  5. Content type: Research article

    Hirudinaria manillensis is an ephemeral, blood-sucking ectoparasite, possessing anticoagulant capacities with potential medical applications. Analysis of codon usage patterns would contribute to our understanding...

    Authors: De-Long Guan, Li-Bin Ma, Muhammad Salabat Khan, Xiu-Xiu Zhang, Sheng-Quan Xu and Juan-Ying Xie

    Citation: BMC Genomics 2018 19:542

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  6. Content type: Research article

    S. latifolia is a model organism for the study of sex chromosome evolution in plants. Its sex chromosomes include large regions in which recombination became gradually suppressed. The regions tend to expand over ...

    Authors: José Luis Rodríguez Lorenzo, Roman Hobza and Boris Vyskot

    Citation: BMC Genomics 2018 19:540

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  7. Content type: Research article

    Spermatogenesis, which is the complex and highly regulated process of producing haploid spermatozoa, involves testis-specific transcripts. Recent studies have discovered that long noncoding RNAs (lncRNAs) are ...

    Authors: Seong Hyeon Hong, Jun Tae Kwon, Jihye Kim, Juri Jeong, Jaehwan Kim, Seonhee Lee and Chunghee Cho

    Citation: BMC Genomics 2018 19:539

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  8. Content type: Research article

    Esophageal squamous cell carcinomas (ESCC) is the fourth most lethal cancer in China. Previous studies reveal several highly conserved mutational processes in ESCC. However, it remains unclear what are the tru...

    Authors: Jintao Guo, Jiankun Huang, Ying Zhou, Yulin Zhou, Liying Yu, Huili Li, Lingyun Hou, Liuwei Zhu, Dandan Ge, Yuanyuan Zeng, Bayasi Guleng and Qiyuan Li

    Citation: BMC Genomics 2018 19:538

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  9. Content type: Research article

    Aspergillus fumigatus is the main causative agent of aspergillosis. Infections rarely occur in immunocompetent individuals, indicating efficient clearance of conidia by pulmonary defense mechanisms. Other aspergi...

    Authors: Natalia Escobar, Ivan D. Valdes, Esther M. Keizer, Soledad R. Ordonez, Robin A. Ohm, Han A. B. Wösten and Hans de Cock

    Citation: BMC Genomics 2018 19:534

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  10. Content type: Research article

    Nitrogen (N) is a key macronutrient essential for plant growth, and its availability has a strong influence on crop development. The application of synthetic N fertilizers on crops has increased substantially ...

    Authors: Sang-Yoon Shin, Jin Seo Jeong, Jae Yun Lim, Taewook Kim, June Hyun Park, Ju-Kon Kim and Chanseok Shin

    Citation: BMC Genomics 2018 19:532

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  11. Content type: Methodology article

    RNA-seq and small RNA-seq are powerful, quantitative tools to study gene regulation and function. Common high-throughput sequencing methods rely on polymerase chain reaction (PCR) to expand the starting materi...

    Authors: Yu Fu, Pei-Hsuan Wu, Timothy Beane, Phillip D. Zamore and Zhiping Weng

    Citation: BMC Genomics 2018 19:531

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  12. Content type: Research article

    Infections with the West Nile virus (WNV) can attack neurological tissues in the host and alter gene expression levels therein. Several individual studies have analyzed these changes in the transcriptome based...

    Authors: Robin Kosch, Julien Delarocque, Peter Claus, Stefanie C. Becker and Klaus Jung

    Citation: BMC Genomics 2018 19:530

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  13. Content type: Methodology article

    The Zika virus (ZIKV) can cause microcephaly and congenital abnormalities in the foetus. Recent studies have provided insights into the evolution of ZIKV from the current and previous outbreaks, but the types ...

    Authors: Hyeji Lee, Mai Phuong Nguyen, Yunhee Choi and Yong-Hak Kim

    Citation: BMC Genomics 2018 19:535

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  14. Content type: Research article

    Genomic methods can provide extraordinary tools to explore the genetic background of wild species and domestic breeds, optimize breeding practices, monitor and limit the spread of recessive diseases, and disco...

    Authors: Romolo Caniglia, Elena Fabbri, Pavel Hulva, Barbora Černá Bolfíková, Milena Jindřichová, Astrid Vik Stronen, Ihor Dykyy, Alessio Camatta, Paolo Carnier, Ettore Randi and Marco Galaverni

    Citation: BMC Genomics 2018 19:533

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  15. Content type: Research article

    Alternative polyadenylation (APA) results in messenger RNA molecules with different 3′ untranslated regions (3’ UTRs), affecting the molecules’ stability, localization, and translation. APA is pervasive and im...

    Authors: Zhuyi Xue, René L. Warren, Ewan A. Gibb, Daniel MacMillan, Johnathan Wong, Readman Chiu, S. Austin Hammond, Chen Yang, Ka Ming Nip, Catherine A. Ennis, Abigail Hahn, Sheila Reynolds and Inanc Birol

    Citation: BMC Genomics 2018 19:536

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  16. Content type: Research article

    Enterococcus faecalis is widely studied as a common gut commensal and a nosocomial pathogen. In fact, Enterococcus faecalis is ubiquitous in nature, and it has been isolated from various niches, including the gas...

    Authors: Qiuwen He, Qiangchuan Hou, Yanjie Wang, Jing Li, Weicheng Li, Lai-Yu Kwok, Zhihong Sun, Heping Zhang and Zhi Zhong

    Citation: BMC Genomics 2018 19:527

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  17. Content type: Research article

    Large-scale molecular changes occur during aging and have many downstream consequences on whole-organism function, such as motor function, learning, and memory. The marine mollusk Aplysia californica can be used ...

    Authors: Justin B. Greer, Michael C. Schmale and Lynne A. Fieber

    Citation: BMC Genomics 2018 19:529

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  18. Content type: Methodology article

    Bacterial genomes have characteristic compositional skews, which are differences in nucleotide frequency between the leading and lagging DNA strands across a segment of a genome. It is thought that these stran...

    Authors: Lena M. Joesch-Cohen, Max Robinson, Neda Jabbari, Christopher G. Lausted and Gustavo Glusman

    Citation: BMC Genomics 2018 19:528

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  19. Content type: Research article

    Anopheles mosquitoes are efficient vectors of human malaria, but it is unknown why they do not transmit viruses as well as Aedes and Culex mosquitoes. The only arbovirus known to be consistently transmitted by An...

    Authors: Guillaume Carissimo, Adrien Pain, Eugeni Belda and Kenneth D. Vernick

    Citation: BMC Genomics 2018 19:526

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  20. Content type: Methodology article

    Common variants have explained less than the amount of heritability expected for complex diseases, which has led to interest in less-common variants and more powerful approaches to the analysis of whole-genome...

    Authors: John Cologne, Lenora Loo, Yurii B. Shvetsov, Munechika Misumi, Philip Lin, Christopher A. Haiman, Lynne R. Wilkens and Loïc Le Marchand

    Citation: BMC Genomics 2018 19:524

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  21. Content type: Methodology article

    Mycoplasma hominis is a human urogenital pathogen involved in gynaecological, neonatal and extra-genital infections. However, no versatile genetic tools are currently available to study the pathogenicity of this ...

    Authors: S. Pereyre, C. Bénard, C. Brès, C. Le Roy, J. P. Mauxion, F. Rideau, P. Sirand-Pugnet, B. Henrich and C. Bébéar

    Citation: BMC Genomics 2018 19:525

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  22. Content type: Research article

    Human Endogenous Retroviruses (HERVs) and Mammalian apparent LTR-retrotransposons (MaLRs) represent the 8% of our genome and are distributed among our 46 chromosomes. These LTR-retrotransposons are thought to ...

    Authors: Marine Mommert, Olivier Tabone, Guy Oriol, Elisabeth Cerrato, Audrey Guichard, Magali Naville, Paola Fournier, Jean-Nicolas Volff, Alexandre Pachot, Guillaume Monneret, Fabienne Venet, Karen Brengel-Pesce, Julien Textoris and François Mallet

    Citation: BMC Genomics 2018 19:522

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