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  1. The GII.4 Sydney 2012 strain of human norovirus (HuNoV) is a pandemic strain that is responsible for the majority of norovirus outbreaks in healthcare settings. The function of the non-structural (NS)1-2 prote...

    Authors: Zabeen Lateef, Gregory Gimenez, Estelle S. Baker and Vernon K. Ward
    Citation: BMC Genomics 2017 18:39
    Content type: Research Article Published on:

  2. Polyploidy and hybridization are both recognized as major forces in evolution. Most of our current knowledge about differences in gene regulation in polyploid hybrids comes from plant studies. The gene express...

    Authors: Li Ren, Chenchen Tang, Wuhui Li, Jialin Cui, Xingjun Tan, Yafeng Xiong, Jie Chen, Jun Wang, Jun Xiao, Yi Zhou, Jing Wang, Min Tao, Chun Zhang and Shaojun Liu
    Citation: BMC Genomics 2017 18:38
    Content type: Research Article Published on:

  3. Soil alkalinity shows significant constraints to crop productivity; however, much less attention has been paid to analyze the effect of soil alkalinity on plant growth and development. Shanrong No. 4 (SR4) is ...

    Authors: Chen Meng, Tai-Yong Quan, Zhong-Yi Li, Kang-Li Cui, Li Yan, Yu Liang, Jiu-Lan Dai, Guang-Min Xia and Shu-Wei Liu
    Citation: BMC Genomics 2017 18:24
    Content type: Research Article Published on:

  4. Cultivated soybean (Glycine max) is a major agricultural crop that provides a crucial source of edible protein and oil. Decreased amounts of saturated palmitic acid and increased amounts of unsaturated oleic acid...

    Authors: Larry J. Leamy, Hengyou Zhang, Changbao Li, Charles Y. Chen and Bao-Hua Song
    Citation: BMC Genomics 2017 18:18
    Content type: Research article Published on:

  5. Small RNAs present in bovine ejaculate can be linked to sperm abnormalities and fertility disorders. At present, quality parameters routinely used in semen evaluation are not fully reliable to predict bull fer...

    Authors: E. Capra, F. Turri, B. Lazzari, P. Cremonesi, T. M. Gliozzi, I. Fojadelli, A. Stella and F. Pizzi
    Citation: BMC Genomics 2017 18:14
    Content type: Research article Published on:

  6. Escherichia coli infections known as colibacillosis constitute a considerable challenge to poultry farmers worldwide, in terms of decreased animal welfare and production economy. Colib...

    Authors: Troels Ronco, Marc Stegger, Rikke Heidemann Olsen, Camilla Sekse, Anne Bang Nordstoga, Tarja Pohjanvirta, Berit Lilje, Ulrike Lyhs, Paal Skytt Andersen and Karl Pedersen
    Citation: BMC Genomics 2017 18:13
    Content type: Research Article Published on:

  8. Polysaccharides often are necessary components of bacterial biofilms and capsules. Production of these biopolymers constitutes a drain on key components in the central carbon metabolism, but so far little is k...

    Authors: Helga Ertesvåg, Håvard Sletta, Mona Senneset, Yi-Qian Sun, Geir Klinkenberg, Therese Aursand Konradsen, Trond E. Ellingsen and Svein Valla
    Citation: BMC Genomics 2017 18:11
    Content type: Research article Published on:

  9. Mammalian development in utero is absolutely dependent on proper placental development, which is ultimately regulated by the placental genome. The regulation of the placental genome can be directly studied by exp...

    Authors: Sam Buckberry, Tina Bianco-Miotto, Stephen J. Bent, Vicki Clifton, Cheryl Shoubridge, Kartik Shankar and Claire T. Roberts
    Citation: BMC Genomics 2017 18:10
    Content type: Research Article Published on:

  10. Stomata regulate photosynthesis and transpiration, and these processes are critical for plant responses to abiotic stresses such as salinity. A barley double haploid population with 108 lines derived from a cr...

    Authors: Xiaohui Liu, Yun Fan, Michelle Mak, Mohammad Babla, Paul Holford, Feifei Wang, Guang Chen, Grace Scott, Gang Wang, Sergey Shabala, Meixue Zhou and Zhong-Hua Chen
    Citation: BMC Genomics 2017 18:9
    Content type: Research article Published on:

  11. Despite important progress in the field of innate immunity, our understanding of host immune responses to parasitic nematode infections lags behind that of responses to microbes. A limiting factor has been the...

    Authors: Jonathan Vadnal, Ramesh Ratnappan, Melissa Keaney, Eric Kenney, Ioannis Eleftherianos, Damien O’Halloran and John M. Hawdon
    Citation: BMC Genomics 2017 18:8
    Content type: Research article Published on:

  12. Chimeric transcripts are commonly defined as transcripts linking two or more different genes in the genome, and can be explained by various biological mechanisms such as genomic rearrangement, read-through or ...

    Authors: Bernardo Rodríguez-Martín, Emilio Palumbo, Santiago Marco-Sola, Thasso Griebel, Paolo Ribeca, Graciela Alonso, Alberto Rastrojo, Begoña Aguado, Roderic Guigó and Sarah Djebali
    Citation: BMC Genomics 2017 18:7
    Content type: Methodology Article Published on:

  13. Wolbachia is a bacterial endosymbiont that naturally infects a wide range of insect species, and causes drastic changes to host biology. Stable infections of Wolbachia in mosquitoes ca...

    Authors: E. P. Caragata, F. S. Pais, L. A. Baton, J. B. L. Silva, M. H. F. Sorgine and L. A. Moreira
    Citation: BMC Genomics 2017 18:6
    Content type: Research Article Published on:

  14. Detection of DNA mutations at very low allele fractions with high accuracy will significantly improve the effectiveness of precision medicine for cancer patients. To achieve this goal through next generation s...

    Authors: Chang Xu, Mohammad R. Nezami Ranjbar, Zhong Wu, John DiCarlo and Yexun Wang
    Citation: BMC Genomics 2017 18:5
    Content type: Methodology Article Published on:

  16. Watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai] is an economically important crop with an attractive ripe fruit that has colorful flesh. Fruit ripening is a complex, genetically programmed process.

    Authors: Qianglong Zhu, Peng Gao, Shi Liu, Zicheng Zhu, Sikandar Amanullah, Angela R. Davis and Feishi Luan
    Citation: BMC Genomics 2017 18:3
    Content type: Research Article Published on:

  17. In the event of an improvised nuclear device detonation, the prompt radiation exposure would consist of photons plus a neutron component that would contribute to the total dose. As neutrons cause more complex ...

    Authors: Constantinos G. Broustas, Yanping Xu, Andrew D. Harken, Guy Garty and Sally A. Amundson
    Citation: BMC Genomics 2017 18:2
    Content type: Research Article Published on:

  18. Solanum pimpinellifolium has high breeding potential for fruit quality traits and has been used as a donor in tomato breeding programs. Unlocking the genetic potential of S. pimpinelli...

    Authors: Ibrahim Celik, Nergiz Gurbuz, Ali Tevfik Uncu, Anne Frary and Sami Doganlar
    Citation: BMC Genomics 2017 18:1
    Content type: Research Article Published on:

  19. Transcriptional changes that contribute to the organism’s longevity and prevent the age-dependent decline of biological functions are not well understood. Here, we overexpressed pro-longevity gene encoding glu...

    Authors: Alexey Moskalev, Mikhail Shaposhnikov, Ekaterina Proshkina, Alexey Belyi, Alexander Fedintsev, Svetlana Zhikrivetskaya, Zulfiya Guvatova, Asiya Sadritdinova, Anastasia Snezhkina, George Krasnov and Anna Kudryavtseva
    Citation: BMC Genomics 2016 17(Suppl 14):1046
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  20. In culturing normal diploid cells, senescence may either happen naturally, in the form of replicative senescence, or it may be a consequence of external challenges such as oxidative stress. Here we present a c...

    Authors: Kamil C. Kural, Neetu Tandon, Mikhail Skoblov, Olga V. Kel-Margoulis and Ancha V. Baranova
    Citation: BMC Genomics 2016 17(Suppl 14):1030
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  21. Amphipods (Crustacea) of Lake Baikal are a very numerous and diverse group of invertebrates generally believed to have originated by adaptive radiation. The evolutionary history and phylogenetic relationships ...

    Authors: Elena V. Romanova, Vladimir V. Aleoshin, Ravil M. Kamaltynov, Kirill V. Mikhailov, Maria D. Logacheva, Elena A. Sirotinina, Alexander Yu. Gornov, Anton S. Anikin and Dmitry Yu. Sherbakov
    Citation: BMC Genomics 2016 17(Suppl 14):1016
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  22. Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. CRC molecular pathogenesis is heterogeneous and may be followed by mutations in oncogenes and tumor suppressor genes, chromosomal a...

    Authors: Anastasiya Vladimirovna Snezhkina, George Sergeevich Krasnov, Andrew Rostislavovich Zaretsky, Alex Zhavoronkov, Kirill Mikhailovich Nyushko, Alexey Alexandrovich Moskalev, Irina Yurievna Karpova, Anastasiya Isaevna Afremova, Anastasiya Valerievna Lipatova, Dmitriy Vladimitovich Kochetkov, Maria Sergeena Fedorova, Nadezhda Nikolaevna Volchenko, Asiya Fayazovna Sadritdinova, Nataliya Vladimirovna Melnikova, Dmitry Vladimirovich Sidorov, Anatoly Yurievich Popov…
    Citation: BMC Genomics 2016 17(Suppl 14):1011
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  23. In recent years, the damage caused by bacterial pathogens to major crops has been increasing worldwide. Pseudomonas syringae is a widespread bacterial species that infects almost all major crops. Different P. syr...

    Authors: Rinat I. Sultanov, Georgij P. Arapidi, Svetlana V. Vinogradova, Vadim M. Govorun, Duglas G. Luster and Alexander N. Ignatov
    Citation: BMC Genomics 2016 17(Suppl 14):1010
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  24. The control of genome stability is relevant for the worldwide BCG vaccine preventing the acute forms of childhood tuberculosis. BCG sub-strains whole genome comparative analysis and revealing the triggers of s...

    Authors: Olga L. Voronina, Marina S. Kunda, Ekaterina I. Aksenova, Andrey N. Semenov, Natalia N. Ryzhova, Vladimir G. Lunin and Alexandr L. Gintsburg
    Citation: BMC Genomics 2016 17(Suppl 14):1009
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  26. Aggressiveness in humans is a hereditary behavioral trait that mobilizes all systems of the body—first of all, the nervous and endocrine systems, and then the respiratory, vascular, muscular, and others—e.g., ...

    Authors: Irina V. Chadaeva, Mikhail P. Ponomarenko, Dmitry A. Rasskazov, Ekaterina B. Sharypova, Elena V. Kashina, Marina Yu Matveeva, Tatjana V. Arshinova, Petr M. Ponomarenko, Olga V. Arkova, Natalia P. Bondar, Ludmila K. Savinkova and Nikolay A. Kolchanov
    Citation: BMC Genomics 2016 17(Suppl 14):995
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  27. The adrenals are known as an important link in pathogenesis of arterial hypertensive disease. The study was directed to the adrenal transcriptome analysis in ISIAH rats with stress-sensitive arterial hypertens...

    Authors: Larisa A. Fedoseeva, Leonid O. Klimov, Nikita I. Ershov, Yury V. Alexandrovich, Vadim M. Efimov, Arcady L. Markel and Olga E. Redina
    Citation: BMC Genomics 2016 17(Suppl 14):989
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  28. Engineering zinc finger protein motifs for specific binding to double-stranded DNA is critical for targeted genome editing. Most existing tools for predicting DNA-binding specificity in zinc fingers are traine...

    Authors: Shayoni Dutta, Spandan Madan and Durai Sundar
    Citation: BMC Genomics 2016 17(Suppl 13):1037
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  29. InCoB became since its inception in 2002 one of the largest annual bioinformatics conferences in the Asia-Pacific region with attendance ranging between 150 and 250 delegates depending on the venue location. I...

    Authors: Christian Schönbach, Chandra Verma, Lawrence Jin Kiat Wee, Peter John Bond and Shoba Ranganathan
    Citation: BMC Genomics 2016 17(Suppl 13):1036
    Content type: Introduction Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  30. Simple sequence repeats (SSRs) have become widely used as molecular markers in plant genetic studies due to their abundance, high allelic variation at each locus and simplicity to analyze using conventional PC...

    Authors: Piyarat Ponyared, Jiradej Ponsawat, Sissades Tongsima, Pusadee Seresangtakul, Chutipong Akkasaeng and Nathpapat Tantisuwichwong
    Citation: BMC Genomics 2016 17(Suppl 13):1035
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  31. Gene copy number divergence between species is a form of genetic polymorphism that contributes significantly to both genome size and phenotypic variation. In plants, copy number expansions of single genes were...

    Authors: Vasantika Suryawanshi, Ina N. Talke, Michael Weber, Roland Eils, Benedikt Brors, Stephan Clemens and Ute Krämer
    Citation: BMC Genomics 2016 17(Suppl 13):1034
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  32. The ability to engineer zinc finger proteins binding to a DNA sequence of choice is essential for targeted genome editing to be possible. Experimental techniques and molecular docking have been successful in p...

    Authors: Shayoni Dutta, Spandan Madan, Harsh Parikh and Durai Sundar
    Citation: BMC Genomics 2016 17(Suppl 13):1033
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  33. Immune cells have to change their gene expression patterns dynamically in response to external stimuli such as lipopolysaccharide (LPS). The gene expression is regulated at multiple steps in eukaryotic cells, ...

    Authors: Yutaro Kumagai, Alexis Vandenbon, Shunsuke Teraguchi, Shizuo Akira and Yutaka Suzuki
    Citation: BMC Genomics 2016 17(Suppl 13):1032
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  34. Proteogenomics is a promising approach for various tasks ranging from gene annotation to cancer research. Databases for proteogenomic searches are often constructed by adding peptide sequences inferred from ge...

    Authors: Honglan Li, Yoon Sung Joh, Hyunwoo Kim, Eunok Paek, Sang-Won Lee and Kyu-Baek Hwang
    Citation: BMC Genomics 2016 17(Suppl 13):1031
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  35. Gemcitabine is used as a standard drug treatment for non-small cell lung cancer (NSCLC), but treatment responses vary among patients. Our previous studies demonstrated that POLA2 + 1747 GG/GA single nucleotide...

    Authors: Vivien Koh, Hsueh Yin Kwan, Woei Loon Tan, Tzia Liang Mah and Wei Peng Yong
    Citation: BMC Genomics 2016 17(Suppl 13):1029
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  36. RNA is often targeted to be localized to the specific subcellular compartments. Specific localization of mRNA is believed to be an important mechanism for targeting their protein products to the locations, whe...

    Authors: Aliaksandr A. Yarmishyn, Maksym Kremenskoy, Arsen O. Batagov, Axel Preuss, Jin Huei Wong and Igor V. Kurochkin
    Citation: BMC Genomics 2016 17(Suppl 13):1028
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  37. Bisulfite sequencing (BS-seq) has become a standard technology to profile genome-wide DNA methylation at single-base resolution. It allows researchers to conduct genome-wise cytosine methylation analyses on is...

    Authors: Sheng-Yao Su, Shu-Hwa Chen, I-Hsuan Lu, Yih-Shien Chiang, Yu-Bin Wang, Pao-Yang Chen and Chung-Yen Lin
    Citation: BMC Genomics 2016 17(Suppl 13):1027
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  38. Lately, biomarker discovery has become one of the most significant research issues in the biomedical field. Owing to the presence of high-throughput technologies, genomic data, such as microarray data and RNA-...

    Authors: Myungjin Moon and Kenta Nakai
    Citation: BMC Genomics 2016 17(Suppl 13):1026
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  39. The ability to sequence the transcriptomes of single cells using single-cell RNA-seq sequencing technologies presents a shift in the scientific paradigm where scientists, now, are able to concurrently investig...

    Authors: Yongli Hu, Takeshi Hase, Hui Peng Li, Shyam Prabhakar, Hiroaki Kitano, See Kiong Ng, Samik Ghosh and Lawrence Jin Kiat Wee
    Citation: BMC Genomics 2016 17(Suppl 13):1025
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  40. Annual hibernation is an adaptation that helps many animals conserve energy during food shortage in winter. This natural cycle is also accompanied by a remodeling of the intestinal immune system, which is an a...

    Authors: Francis Cheng-Hsuan Weng, Yi-Ju Yang and Daryi Wang
    Citation: BMC Genomics 2016 17(Suppl 13):1024
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  41. The temporal and spatial-specific expression pattern of a transcript in multiple tissues and cell types can indicate key clues about its function. While several gene atlas available online as pre-computed data...

    Authors: Mei Hou, Feng Tian, Shuai Jiang, Lei Kong, Dechang Yang and Ge Gao
    Citation: BMC Genomics 2016 17(Suppl 13):1023
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  42. Though glioblastoma multiforme (GBM) is the most frequently occurring brain malignancy in adults, clinical treatment still faces challenges due to poor prognoses and tumor relapses. Recently, microRNAs (miRNAs...

    Authors: Srinivasulu Yerukala Sathipati, Hui-Ling Huang and Shinn-Ying Ho
    Citation: BMC Genomics 2016 17(Suppl 13):1022
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 13

  43. Enterohaemorrhagic Escherichia coli (EHEC), like E. coli O157:H7 are frequently detected in bovine faecal samples at slaughter. Cattle do not show clinical symptoms upon infection, but for humans the consequences...

    Authors: E. Kieckens, J. Rybarczyk, R. W. Li, D. Vanrompay and E. Cox
    Citation: BMC Genomics 2016 17:1049
    Content type: Research article Published on:

  44. Many gram-negative bacteria use type III secretion systems (T3SSs) to translocate effector proteins into host cells. T3SS effectors can give some bacteria a competitive edge over others within the same environ...

    Authors: Christopher K. Hobbs, Vanessa L. Porter, Maxwell L. S. Stow, Bupe A. Siame, Herbert H. Tsang and Ka Yin Leung
    Citation: BMC Genomics 2016 17:1048
    Content type: Research article Published on:

  45. The metabolite content of a seed and its ability to germinate are determined by genetic makeup and environmental effects during development. The interaction between genetics, environment and seed metabolism an...

    Authors: Leah Rosental, Adi Perelman, Noa Nevo, David Toubiana, Talya Samani, Albert Batushansky, Noga Sikron, Yehoshua Saranga and Aaron Fait
    Citation: BMC Genomics 2016 17:1047
    Content type: Research article Published on:

  46. Switchgrass, a warm-season perennial grass studied as a potential dedicated biofuel feedstock, is classified into two main taxa – lowland and upland ecotypes – that differ in morphology and habitat of adaptati...

    Authors: Desalegn D. Serba, Srinivasa Rao Uppalapati, Nick Krom, Shreyartha Mukherjee, Yuhong Tang, Kirankumar S. Mysore and Malay C. Saha
    Citation: BMC Genomics 2016 17:1040
    Content type: Research article Published on:

  47. Wild relatives of wheat play a significant role in wheat improvement as a source of genetic diversity. Stem rust disease of wheat causes significant yield losses at the global level and stem rust pathogen race...

    Authors: Erena A. Edae, Pablo D. Olivera, Yue Jin, Jesse A. Poland and Matthew N. Rouse
    Citation: BMC Genomics 2016 17:1039
    Content type: Research article Published on:

  48. The cyclic peptide toxins of Amanita mushrooms, such as α-amanitin and phalloidin, are encoded by the “MSDIN” gene family and ribosomally biosynthesized. Based on partial genome sequence and PCR analysis, some me...

    Authors: Jane A. Pulman, Kevin L. Childs, R. Michael Sgambelluri and Jonathan D. Walton
    Citation: BMC Genomics 2016 17:1038
    Content type: Research article Published on:

  49. Antimicrobial peptides from plants present mechanisms of action that are different from those of conventional defense agents. They are under-explored but have a potential as commercial antimicrobials. Bell pep...

    Authors: Patrícia Dias Games, Elói Quintas Gonçalves daSilva, Meire de Oliveira Barbosa, Hebréia Oliveira Almeida-Souza, Patrícia Pereira Fontes, Marcos Jorge deMagalhães-Jr, Paulo Roberto Gomes Pereira, Maura Vianna Prates, Gloria Regina Franco, Alessandra Faria-Campos, Sérgio Vale Aguiar Campos and Maria Cristina Baracat-Pereira
    Citation: BMC Genomics 2016 17(Suppl 12):999
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 12

  50. Lysine acetylation in proteins is a ubiquitous and conserved post-translational modification, playing a critical regulatory role in almost every aspect of living cells. Although known for many years, its funct...

    Authors: Shanyue Zhou, Qianqian Yang, Changfa Yin, Lin Liu and Wenxing Liang
    Citation: BMC Genomics 2016 17:1019
    Content type: Research article Published on:

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BMC Genomics

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