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  1. Chromosomes are organized into units called topologically associated domains (TADs). TADs dictate regulatory landscapes and other DNA-dependent processes. Even though various factors that contribute to the spe...

    Authors: Benjamin Soibam and Ayzhamal Zhamangaraeva
    Citation: BMC Genomics 2021 22:397
  2. Transmission of pathogens by vector mosquitoes is intrinsically linked with mosquito’s reproductive strategy because anautogenous mosquitoes require vertebrate blood to develop a batch of eggs. Each cycle of e...

    Authors: Dilip K. Nag, Constentin Dieme, Pascal Lapierre, Erica Lasek-Nesselquist and Laura D. Kramer
    Citation: BMC Genomics 2021 22:396
  3. Domain of unknown function 668 (DUF668) may play a crucial role in the plant growth and developmental response to adverse stress. However, our knowledge of the function of the DUF668 gene family is limited.

    Authors: Jieyin Zhao, Peng Wang, Wenju Gao, Yilei Long, Yuxiang Wang, Shiwei Geng, Xuening Su, Yang Jiao, Quanjia Chen and Yanying Qu
    Citation: BMC Genomics 2021 22:395
  4. The pine wood nematode Bursaphelenchus xylophilus is a destructive pest of Pinus trees worldwide and lacks effective control measures. Screening for nematotoxic proteins has been undertaken to develop new strateg...

    Authors: Ye Chen, Xiang Zhou, Kai Guo, Sha-Ni Chen and Xiu Su
    Citation: BMC Genomics 2021 22:394
  5. Somatic embryogenesis (SE) is the process in which somatic embryos develop from somatic tissue in vitro on medium in most cases supplemented with growth regulators. Knowledge of genes involved in regulation of...

    Authors: Sonali Sachin Ranade and Ulrika Egertsdotter
    Citation: BMC Genomics 2021 22:392

    The Correction to this article has been published in BMC Genomics 2021 22:515

  6. Spodoptera frugiperda is a serious pest that causes devastating losses to many major crops, including corn, rice, sugarcane, and peanut. Camptothecin (CPT) is a bioactive secondary metabolite of the woody plant C...

    Authors: Benshui Shu, Yan Zou, Haikuo Yu, Wanying Zhang, Xiangli Li, Liang Cao and Jintian Lin
    Citation: BMC Genomics 2021 22:391
  7. Intron mediated enhancement (IME) is the potential of introns to enhance the expression of its respective gene. This essential function of introns has been observed in a wide range of species, including fungi,...

    Authors: Georg Back and Dirk Walther
    Citation: BMC Genomics 2021 22:390
  8. Whole genome sequencing of cultured pathogens is the state of the art public health response for the bioinformatic source tracking of illness outbreaks. Quasimetagenomics can substantially reduce the amount of...

    Authors: Seth Commichaux, Kiran Javkar, Padmini Ramachandran, Niranjan Nagarajan, Denis Bertrand, Yi Chen, Elizabeth Reed, Narjol Gonzalez-Escalona, Errol Strain, Hugh Rand, Mihai Pop and Andrea Ottesen
    Citation: BMC Genomics 2021 22:389
  9. Elucidating the effects of geography and selection on genetic variation is critical for understanding the relative importance of adaptation in driving differentiation and identifying the environmental factors ...

    Authors: Li Liu, Zhen Wang, Yingjuan Su and Ting Wang
    Citation: BMC Genomics 2021 22:388
  10. The maize husk consists of numerous leafy layers and plays vital roles in protecting the ear from pathogen infection and dehydration. Teosinte, the wild ancestor of maize, has about three layers of small husk ...

    Authors: Xiaolei Zhang, Ming Lu, Aiai Xia, Tao Xu, Zhenhai Cui, Ruiying Zhang, Wenguo Liu and Yan He
    Citation: BMC Genomics 2021 22:386
  11. Mycobacterium abscessus (MAB) is a widely disseminated pathogenic non-tuberculous mycobacterium (NTM). Like with the M. tuberculosis complex (MTBC), excreted / secreted (ES) proteins play an essential role for it...

    Authors: Fernanda Cornejo-Granados, Thomas A. Kohl, Flor Vásquez Sotomayor, Sönke Andres, Rogelio Hernández-Pando, Juan Manuel Hurtado-Ramirez, Christian Utpatel, Stefan Niemann, Florian P. Maurer and Adrian Ochoa-Leyva
    Citation: BMC Genomics 2021 22:385
  12. Leaf color is an important ornamental trait of colored-leaf plants. The change of leaf color is closely related to the synthesis and accumulation of anthocyanins in leaves. Acer pseudosieboldianum is a colored-le...

    Authors: Yu-Fu Gao, Dong-Hui Zhao, Jia-Qi Zhang, Jia-Shuo Chen, Jia-Lin Li, Zhuo Weng and Li-Ping Rong
    Citation: BMC Genomics 2021 22:383
  13. The fungus Parastagonospora nodorum causes septoria nodorum blotch (SNB) of wheat (Triticum aestivum) and is a model species for necrotrophic plant pathogens. The genome assembly of reference isolate Sn15 was fir...

    Authors: Stefania Bertazzoni, Darcy A. B. Jones, Huyen T. Phan, Kar-Chun Tan and James K. Hane
    Citation: BMC Genomics 2021 22:382
  14. Birds have various plumage color patterns, and spot is a common phenotype. Herein, we conducted genome-wide association studies (GWAS) in a population of 225 ducks with different sized black spots to reveal th...

    Authors: Yang Xi, Qian Xu, Qin Huang, Shengchao Ma, Yushi Wang, Chunchun Han, Rongping Zhang, Jiwen Wang, Hehe Liu and Liang Li
    Citation: BMC Genomics 2021 22:381
  15. Speed congenics is an important tool for creating congenic mice to investigate gene functions, but current SNP genotyping methods for speed congenics are expensive. These methods usually rely on chip or array ...

    Authors: Kimberly R. Andrews, Samuel S. Hunter, Brandi K. Torrevillas, Nora Céspedes, Sarah M. Garrison, Jessica Strickland, Delaney Wagers, Gretchen Hansten, Daniel D. New, Matthew W. Fagnan and Shirley Luckhart
    Citation: BMC Genomics 2021 22:378
  16. Subfertility is a major problem in modern horse breeding. Especially, mares without clinical signs of reproductive diseases, without known uterine pathogens and no evidence of inflammation but not becoming pre...

    Authors: Katharina S. Weber, Karen Wagener, Miguel Blanco, Stefan Bauersachs and Heinrich Bollwein
    Citation: BMC Genomics 2021 22:377
  17. The genus Rhododendron L. has been widely cultivated for hundreds of years around the world. Members of this genus are known for great ornamental and medicinal value. Owing to advances in sequencing technology, g...

    Authors: Ningyawen Liu, Lu Zhang, Yanli Zhou, Mengling Tu, Zhenzhen Wu, Daping Gui, Yongpeng Ma, Jihua Wang and Chengjun Zhang
    Citation: BMC Genomics 2021 22:376
  18. Members of the WRKY protein family, one of the largest transcription factor families in plants, are involved in plant growth and development, signal transduction, senescence, and stress resistance. However, li...

    Authors: Hongmei Yuan, Wendong Guo, Lijuan Zhao, Ying Yu, Si Chen, Lei Tao, Lili Cheng, Qinghua Kang, Xixia Song, Jianzhong Wu, Yubo Yao, Wengong Huang, Ying Wu, Yan Liu, Xue Yang and Guangwen Wu
    Citation: BMC Genomics 2021 22:375
  19. 20-hydroxyecdysone (20E) plays important roles in insect molting and metamorphosis. 20E-induced autophagy has been detected during the larval–pupal transition in different insects. In Bombyx mori, autophagy is in...

    Authors: Huili Qiao, Jingya Wang, Yuanzhuo Wang, Juanjuan Yang, Bofan Wei, Miaomiao Li, Bo Wang, Xiaozhe Li, Yang Cao, Ling Tian, Dandan Li, Lunguang Yao and Yunchao Kan
    Citation: BMC Genomics 2021 22:374
  20. Spiroplasma citri comprises a bacterial complex that cause diseases in citrus, horseradish, carrot, sesame, and also infects a wide array of ornamental and weed species. S. citri is transmitted in a persistent pr...

    Authors: Rachel Rattner, Shree Prasad Thapa, Tyler Dang, Fatima Osman, Vijayanandraj Selvaraj, Yogita Maheshwari, Deborah Pagliaccia, Andres S. Espindola, Subhas Hajeri, Jianchi Chen, Gitta Coaker, Georgios Vidalakis and Raymond Yokomi
    Citation: BMC Genomics 2021 22:373
  21. Phytophthora capsici root rot (PRR) is a disastrous disease in peppers (Capsicum spp.) caused by soilborne oomycete with typical symptoms of necrosis and constriction at the basal stem and consequent plant wiltin...

    Authors: Jin-Song Du, Lin-Feng Hang, Qian Hao, Hai-Tao Yang, Siyad Ali, Radwa Salah Ezaat Badawy, Xiao-Yu Xu, Hua-Qiang Tan, Li-Hong Su, Huan-Xiu Li, Kai-Xi Zou, Yu Li, Bo Sun, Li-Jin Lin and Yun-Song Lai
    Citation: BMC Genomics 2021 22:372
  22. Brazil is the third country most affected by Coronavirus disease-2019 (COVID-19), but viral evolution in municipality resolution is still poorly understood in Brazil and it is crucial to understand the epidemi...

    Authors: Vinícius Bonetti Franceschi, Gabriel Dickin Caldana, Amanda de Menezes Mayer, Gabriela Bettella Cybis, Carla Andretta Moreira Neves, Patrícia Aline Gröhs Ferrareze, Meriane Demoliner, Paula Rodrigues de Almeida, Juliana Schons Gularte, Alana Witt Hansen, Matheus Nunes Weber, Juliane Deise Fleck, Ricardo Ariel Zimerman, Lívia Kmetzsch, Fernando Rosado Spilki and Claudia Elizabeth Thompson
    Citation: BMC Genomics 2021 22:371
  23. Improving yield prediction and selection efficiency is critical for tree breeding. This is vital for macadamia trees with the time from crossing to production of new cultivars being almost a quarter of a centu...

    Authors: Katie M. O’Connor, Ben J. Hayes, Craig M. Hardner, Mobashwer Alam, Robert J. Henry and Bruce L. Topp
    Citation: BMC Genomics 2021 22:370
  24. Systematic studies on the development and adaptation of hindlimb muscles in anura amphibians are rare. Here, we integrated analysis of transcriptome and histomorphological data for the hindlimb thigh muscle of Od...

    Authors: Yilin Shu, Jun He, Huijuan Zhang, Guangxuan Liu, Shikun Li, Shuaitao Deng and Hailong Wu
    Citation: BMC Genomics 2021 22:369
  25. Colonization of dairy cows by Staphylococcus aureus (S. aureus), especially those which are multi-drug resistant and toxin producing, is a concern for animal health and well-being as well as public health. The ob...

    Authors: Kruthika Patel, Sandra M. Godden, Erin E. Royster, Brian A. Crooker, Timothy J. Johnson, Emily A. Smith and Srinand Sreevatsan
    Citation: BMC Genomics 2021 22:367
  26. A total of 179 Shiga toxin-producing Escherichia coli (STEC) complete genomes were analyzed in terms of serotypes, prophage coding regions, and stx gene variants and their distribution. We further examined the ge...

    Authors: Graça Pinto, Marta Sampaio, Oscar Dias, Carina Almeida, Joana Azeredo and Hugo Oliveira
    Citation: BMC Genomics 2021 22:366
  27. A healthy microbiome influences host physiology through a mutualistic relationship, which can be important for the host to cope with cellular stress by promoting fitness and survival. The mammalian microbiome ...

    Authors: Orçun Haçariz, Charles Viau, Farial Karimian and Jianguo Xia
    Citation: BMC Genomics 2021 22:364
  28. Reference-guided read alignment and variant genotyping are prone to reference allele bias, particularly for samples that are greatly divergent from the reference genome. A Hereford-based assembly is the widely...

    Authors: Audald Lloret-Villas, Meenu Bhati, Naveen Kumar Kadri, Ruedi Fries and Hubert Pausch
    Citation: BMC Genomics 2021 22:363
  29. Hybridization, which can quickly merge two or more divergent genomes and form new allopolyploids, is an important technique in fish genetic breeding. However, the merged subgenomes must adjust and coexist with...

    Authors: Wuhui Li, Shi Wang, Jie Hu, Chenchen Tang, Chang Wu, Junmei Liu, Li Ren, Chengfei Sun, Junjian Dong, Shaojun Liu and Xing Ye
    Citation: BMC Genomics 2021 22:362
  30. Soybean is an important legume crop and has significant agricultural and economic value. Previous research has shown that the AT-Hook Motif Nuclear Localized (AHL) gene family is highly conserved in land plants, ...

    Authors: Min Wang, Bowei Chen, Wei Zhou, Linan Xie, Lishan Wang, Yonglan Zhang and Qingzhu Zhang
    Citation: BMC Genomics 2021 22:361
  31. Rosaceae species are economically highly relevant crops. Their cultivation systems are constrained by phytopathogens causing severe losses. Plants respond to invading pathogens through signaling mechanisms, a ...

    Authors: Laura Foix, Anna Nadal, Maja Zagorščak, Živa Ramšak, Anna Esteve-Codina, Kristina Gruden and Maria Pla
    Citation: BMC Genomics 2021 22:360
  32. Despite the growing interest in the female side of copulatory interactions, the roles played by differential expression and alternative splicing mechanisms of pre-RNA on tissues outside of the reproductive tract ...

    Authors: Fernando Diaz, Carson W. Allan, Therese Ann Markow, Jeremy M. Bono and Luciano M. Matzkin
    Citation: BMC Genomics 2021 22:359
  33. Authors: Shruti Sinai Borker, Aman Thakur, Sanjeet Kumar, Sareeka Kumari, Rakshak Kumar and Sanjay Kumar
    Citation: BMC Genomics 2021 22:358

    The original article was published in BMC Genomics 2021 22:307

  34. Detection of copy number variations (CNVs) from high-throughput next-generation whole-genome sequencing (WGS) data has become a widely used research method during the recent years. However, only a little is kn...

    Authors: Johannes Smolander, Sofia Khan, Kalaimathy Singaravelu, Leni Kauko, Riikka J. Lund, Asta Laiho and Laura L. Elo
    Citation: BMC Genomics 2021 22:357
  35. Chile peppers (Capsicum spp.) are among the most important horticultural crops in the world due to their number of uses. They are considered a major cultural and economic crop in the state of New Mexico in the Un...

    Authors: Dennis N. Lozada, Madhav Bhatta, Danise Coon and Paul W. Bosland
    Citation: BMC Genomics 2021 22:356
  36. Brown marmorated stink bug (BMSB), Halyomorpha halys (Hemiptera: Pentatomidae) is native to East Asia but has invaded many countries in the world. BMSB is a polyphagous insect pest and causes significant economic...

    Authors: Juncong Yan, Gábor Vétek, Chandan Pal, Jinping Zhang, Rania Gmati, Qing-Hai Fan, Disna N. Gunawardana, Allan Burne, Diane Anderson, Rebijith Kayattukandy Balan, Sherly George, Péter Farkas and Dongmei Li
    Citation: BMC Genomics 2021 22:355
  37. Copy number variations (CNVs) are a major type of structural genomic variants that underlie genetic architecture and phenotypic variation of complex traits, not only in humans, but also in livestock animals. W...

    Authors: Anna Carolina Fernandes, Vinicius Henrique da Silva, Carolina Purcell Goes, Gabriel Costa Monteiro Moreira, Thaís Fernanda Godoy, Adriana Mércia Guaratini Ibelli, Jane de Oliveira Peixoto, Maurício Egídio Cantão, Mônica Corrêa Ledur, Fernanda Marcondes de Rezende and Luiz Lehmann Coutinho
    Citation: BMC Genomics 2021 22:354
  38. Polygonum cuspidatum Sieb. et Zucc. is a well-known medicinal plant whose pharmacological effects derive mainly from its stilbenes, anthraquinones, and flavonoids. These compounds accumulate differentially in the...

    Authors: Xiaowei Wang, Hongyan Hu, Zhijun Wu, Haili Fan, Guowei Wang, Tuanyao Chai and Hong Wang
    Citation: BMC Genomics 2021 22:353
  39. The serine carboxypeptidase-like protein (SCPL) family plays a vital role in stress response, growth, development and pathogen defense. However, the identification and functional analysis of SCPL gene family memb...

    Authors: Xiaomin Xu, Lili Zhang, Wan Zhao, Liang Fu, Yuxuan Han, Keke Wang, Luyu Yan, Ye Li, Xiao-Hong Zhang and Dong-Hong Min
    Citation: BMC Genomics 2021 22:350
  40. Changshun green-shell laying hens are unique to Guizhou Province, China, and have high egg quality. Improving egg production performance has become an important breeding task, and in recent years, the developm...

    Authors: Ren Mu, Yi-yin Yu, Tuya Gegen, Di Wen, Fen Wang, Zhi Chen and Wen-bin Xu
    Citation: BMC Genomics 2021 22:349
  41. Infectious Salmonid Anaemia Virus (ISAV) causes a notifiable disease that poses a large threat for Atlantic salmon (Salmo salar) aquaculture worldwide. There is no fully effective treatment or vaccine, and theref...

    Authors: O. Gervais, A. Barria, A. Papadopoulou, R. L. Gratacap, B. Hillestad, A. E. Tinch, S. A. M. Martin, D. Robledo and R. D. Houston
    Citation: BMC Genomics 2021 22:345

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