Skip to main content

Articles

6358 result(s) for 'general transcription factors vs specific' within BMC Genomics

Page 41 of 128

  1. Chemostat cultures are commonly used in production of cellular material for systems-wide biological studies. We have used the novel TRAC (transcript analysis with aid of affinity capture) method to study expre...

    Authors: Jari J Rautio, Bart A Smit, Marilyn Wiebe, Merja Penttilä and Markku Saloheimo
    Citation: BMC Genomics 2006 7:247
    Content type: Research article Published on:

  2. Canga is the Brazilian term for the savanna-like vegetation harboring several endemic species on iron-rich rocky outcrops, usually considered for mining activities. Parkia platycephala Benth. and Stryphnodendron ...

    Authors: Mariana Costa Dias, Cecílio Caldeira, Markus Gastauer, Silvio Ramos and Guilherme Oliveira
    Citation: BMC Genomics 2022 23:313
    Content type: Research Published on:

  3. Significant differences in immune responses, prevalence or susceptibility of diseases and treatment responses have been described between males and females. Despite this, sex-differentiation analysis of the ge...

    Authors: Collins K. Boahen, Hannah Abee, Isis Ricaño Ponce, Leo A. B. Joosten, Mihai G. Netea and Vinod Kumar
    Citation: BMC Genomics 2024 25:154
    Content type: Research Published on:

  4. Serine proteases are one of the most abundant groups of proteolytic enzymes found in all the kingdoms of life. While studies have established significant roles for many prokaryotic serine proteases in several ...

    Authors: Lokesh P Tripathi and R Sowdhamini
    Citation: BMC Genomics 2008 9:549
    Content type: Research article Published on:

  5. In an earlier study, we hypothesized that genomic segments with different sequence organization patterns (OPs) might display functional specificity despite their similar GC content. Here we tested this hypothe...

    Authors: Arnon Paz, Svetlana Frenkel, Sagi Snir, Valery Kirzhner and Abraham B Korol
    Citation: BMC Genomics 2014 15:252
    Content type: Research article Published on:

  6. Along with trophoblast elongation (Days 10 to 12), estradiol is secreted in increasing amounts for recognition of pregnancy. Endometrial secretions driven by ovarian progesterone and conceptus signals are esse...

    Authors: Shuqin Zeng, Jochen Bick, Susanne E. Ulbrich and Stefan Bauersachs
    Citation: BMC Genomics 2018 19:459
    Content type: Research article Published on:

  7. Successful achievement of early folliculogenesis is crucial for female reproductive function. The process is finely regulated by cell-cell interactions and by the coordinated expression of genes in both the oo...

    Authors: Agnes Bonnet, Claudia Bevilacqua, Francis Benne, Loys Bodin, Corinne Cotinot, Laurence Liaubet, Magali Sancristobal, Julien Sarry, Elena Terenina, Patrice Martin, Gwenola Tosser-Klopp and Beatrice Mandon-Pepin
    Citation: BMC Genomics 2011 12:417
    Content type: Research article Published on:

  8. Cotton fiber, a highly elongated, thickened single cell of the seed epidermis, is a powerful cell wall research model. Fiber length, largely determined during the elongation stage, is a key property of fiber q...

    Authors: Lei Fang, Ruiping Tian, Xinghe Li, Jiedan Chen, Sen Wang, Peng Wang and Tianzhen Zhang
    Citation: BMC Genomics 2014 15:838
    Content type: Research article Published on:

  9. Monosporascus cannonballus is the main causal agent of melon vine decline disease. Several studies have been carried out mainly focused on the study of the penetration of this pathogen into melon roots, the evalu...

    Authors: Cristina Roig, Ana Fita, Gabino Ríos, John P Hammond, Fernando Nuez and Belén Picó
    Citation: BMC Genomics 2012 13:601
    Content type: Research article Published on:

  10. Due to the recent rapid development in ChIP-seq technologies, which uses high-throughput next-generation DNA sequencing to identify the targets of Chromatin Immunoprecipitation, there is an increasing amount o...

    Authors: Christina Schweikert, Stuart Brown, Zuojian Tang, Phillip R Smith and D Frank Hsu
    Citation: BMC Genomics 2012 13(Suppl 8):S12
    Content type: Research Published on:

    This article is part of a Supplement: Volume 13 Supplement 8

  11. Genes and signalling pathways involved in pluripotency have been studied extensively in mouse and human pre-implantation embryos and embryonic stem (ES) cells. The unsuccessful attempts to generate ES cell lin...

    Authors: Bas Brinkhof, Helena TA van Tol, Marian JA Groot Koerkamp, Frank M Riemers, Sascha G IJzer, Kaveh Mashayekhi, Henk P Haagsman and Bernard AJ Roelen
    Citation: BMC Genomics 2015 16:277
    Content type: Research article Published on:

  12. Salvia miltiorrhiza is one of the most important traditional Chinese medicinal plants with high medicinal value. Gibberellins are growth-promoting phytohormones that regulate numerous growth and developmental pro...

    Authors: Wenrui Li, Chuangfeng Liu, Jingling Liu, Zhenqing Bai and Zongsuo Liang
    Citation: BMC Genomics 2020 21:727
    Content type: Research article Published on:

  13. Systematic research on fish immunogenetics is indispensable in understanding the origin and evolution of immune systems. This has long been a challenging task because of the limited number of deep sequencing t...

    Authors: Li-xin Xiang, Ding He, Wei-ren Dong, Yi-wen Zhang and Jian-zhong Shao
    Citation: BMC Genomics 2010 11:472
    Content type: Research article Published on:

  14. The reporting of the first draft of the human genome in 2000 brought with it much hope for the future in what was felt as a paradigm shift toward improved health outcomes. Indeed, we have now mapped the majori...

    Authors: K. Blighe, L. DeDionisio, K. A. Christie, B. Chawes, S. Shareef, T. Kakouli-Duarte, C. Chao-Shern, V. Harding, R. S. Kelly, L. Castellano, J. Stebbing, J. A. Lasky-Su, M. A. Nesbit and C. B. T. Moore
    Citation: BMC Genomics 2018 19:595
    Content type: Review Published on:

  15. When compared to skin, oral mucosal wounds heal rapidly and with reduced scar formation. Recent studies suggest that intrinsic differences in inflammation, growth factor production, levels of stem cells, and c...

    Authors: Lin Chen, Zarema H Arbieva, Shujuan Guo, Phillip T Marucha, Thomas A Mustoe and Luisa A DiPietro
    Citation: BMC Genomics 2010 11:471
    Content type: Research article Published on:

  16. Plant microRNAs are short (~21 nt) non-coding molecules that regulate gene expression by targeting the mRNA cleavage or protein translation inhibition. In this manner, they play many important roles in the cel...

    Authors: Anna Lukasik, Halina Pietrykowska, Leszek Paczek, Zofia Szweykowska-Kulinska and Piotr Zielenkiewicz
    Citation: BMC Genomics 2013 14:801
    Content type: Research article Published on:

  17. Embryonic genome activation (EGA) is a critical event for the preimplantation embryo, which is manifested by changes in chromatin structure, transcriptional machinery, expression of embryonic genes, and degrad...

    Authors: Alper Uzun, Nelida Rodriguez-Osorio, Abdullah Kaya, Hongfeng Wang, John J Parrish, Valentin A Ilyin and Erdogan Memili
    Citation: BMC Genomics 2009 10:183
    Content type: Research article Published on:

  18. The parasite Varroa destructor represents a significant threat to honeybee colonies. Indeed, development of Varroa infestation within colonies, if left untreated, often leads to the death of the colony. Although ...

    Authors: Fanny Mondet, Andrea Rau, Christophe Klopp, Marine Rohmer, Dany Severac, Yves Le Conte and Cedric Alaux
    Citation: BMC Genomics 2018 19:328
    Content type: Research article Published on:

  19. The ubiquitin 26S proteasome system (UPS) selectively degrades cellular proteins, which results in physiological changes to eukaryotic cells. F-box proteins are substrate adaptors within the UPS and are respon...

    Authors: Lauren E. Gonzalez, Kristen Keller, Karen X. Chan, Megan M. Gessel and Bryan C. Thines
    Citation: BMC Genomics 2017 18:533
    Content type: Research article Published on:

  20. Structural variations (SVs) have recently become a topic of great interest in the area of genetic diversity and trait regulation. As genomic sequencing technologies have rapidly advanced, longer reads have bee...

    Authors: Yueyuan Liu, Mingyue Zhang, Runze Wang, Benping Li, Yafei Jiang, Manyi Sun, Yaojun Chang and Jun Wu
    Citation: BMC Genomics 2022 23:830
    Content type: Research Published on:

  22. The contribution of mitogen-activated protein kinase (MAPK) cascades to plant growth and development has been widely studied, but this knowledge has not yet been extended to the medicinal plant Salvia miltiorrhiz...

    Authors: Yongfeng Xie, Meiling Ding, Bin Zhang, Jie Yang, Tianlin Pei, Pengda Ma and Juane Dong
    Citation: BMC Genomics 2020 21:630
    Content type: Research article Published on:

  23. MicroRNAs (miRNAs) simultaneously target many transcripts through partial complementarity binding, and have emerged as a key type of post-transcriptional regulator for gene expression. How miRNA accomplishes i...

    Authors: Sheng-Da Hsu, Hsi-Yuan Huang, Chih-Hung Chou, Yi-Ming Sun, Ming-Ta Hsu and Ann-Ping Tsou
    Citation: BMC Genomics 2015 16(Suppl 2):S12
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 16 Supplement 2

  24. Saliva of blood-sucking arthropods contains a cocktail of antihemostatic agents and immunomodulators that help blood feeding. Mosquitoes additionally feed on sugar meals and have specialized regions of their g...

    Authors: José MC Ribeiro, Bruno Arcà, Fabrizio Lombardo, Eric Calvo, Van My Phan, Prafulla K Chandra and Stephen K Wikel
    Citation: BMC Genomics 2007 8:6
    Content type: Research article Published on:

  25. Development and application of DNA-based methods to distinguish highly virulent isolates of Fusarium oxysporum f. sp. koae [Fo koae; cause of koa wilt disease on Acacia koa (koa)] will help disease management thr...

    Authors: John T. Dobbs, Mee-Sook Kim, Nicklos S. Dudley, Ned B. Klopfenstein, Aileen Yeh, Robert D. Hauff, Tyler C. Jones, R. Kasten Dumroese, Philip G. Cannon and Jane E. Stewart
    Citation: BMC Genomics 2020 21:764
    Content type: Research article Published on:

  26. Epigenetic variation may result from selection for complex traits related to metabolic processes or appear in the course of adaptation to mediate responses to exogenous stressors. Moreover epigenetic marks, in...

    Authors: Siriluck Ponsuksili, Nares Trakooljul, Sajjanar Basavaraj, Frieder Hadlich, Eduard Murani and Klaus Wimmers
    Citation: BMC Genomics 2019 20:492
    Content type: Research article Published on:

  27. Major secondary metabolites, including flavonoids, caffeine, and theanine, are important components of tea products and are closely related to the taste, flavor, and health benefits of tea. Secondary metabolit...

    Authors: Chun-Fang Li, Yan Zhu, Yao Yu, Qiong-Yi Zhao, Sheng-Jun Wang, Xin-Chao Wang, Ming-Zhe Yao, Da Luo, Xuan Li, Liang Chen and Ya-Jun Yang
    Citation: BMC Genomics 2015 16:560
    Content type: Research article Published on:

  28. Cotton (Gossypium hirsutum L.) is a major fiber crop that is grown worldwide; it faces extensive damage from sap-sucking insects, including aphids and whiteflies. Genome-wide transcriptome analysis was performed ...

    Authors: Neeraj Kumar Dubey, Ridhi Goel, Alok Ranjan, Asif Idris, Sunil Kumar Singh, Sumit K Bag, Krishnappa Chandrashekar, Kapil Deo Pandey, Pradhyumna Kumar Singh and Samir V Sawant
    Citation: BMC Genomics 2013 14:241
    Content type: Research article Published on:

  29. Epigenetic information can be used to identify clinically relevant genomic variants single nucleotide polymorphisms (SNPs) of functional importance in cancer development. Super-enhancers are cell-specific DNA ...

    Authors: Verena Zuber, Francesco Bettella, Aree Witoelar, Ole A. Andreassen, Ian G. Mills and Alfonso Urbanucci
    Citation: BMC Genomics 2017 18:270
    Content type: Research article Published on:

  30. A limiting factor of cDNA microarray technology is the need for a substantial amount of RNA per labeling reaction. Thus, 20–200 micro-grams total RNA or 0.5–2 micro-grams poly (A) RNA is typically required for...

    Authors: Vigdis Nygaard, Anders Løland, Marit Holden, Mette Langaas, Håvard Rue, Fang Liu, Ola Myklebost, Øystein Fodstad, Eivind Hovig and Birgitte Smith-Sørensen
    Citation: BMC Genomics 2003 4:11
    Content type: Research article Published on:

  31. The Norway lobster, Nephrops norvegicus, is economically important in European fisheries and is a key organism in local marine ecosystems. Despite multi-faceted scientific interest in this species, our current kn...

    Authors: Guiomar Rotllant, Tuan Viet Nguyen, Valerio Sbragaglia, Lifat Rahi, Kevin J. Dudley, David Hurwood, Tomer Ventura, Joan B. Company, Vincent Chand, Jacopo Aguzzi and Peter B. Mather
    Citation: BMC Genomics 2017 18:622
    Content type: Research article Published on:

  32. The adrenals are known as an important link in pathogenesis of arterial hypertensive disease. The study was directed to the adrenal transcriptome analysis in ISIAH rats with stress-sensitive arterial hypertens...

    Authors: Larisa A. Fedoseeva, Leonid O. Klimov, Nikita I. Ershov, Yury V. Alexandrovich, Vadim M. Efimov, Arcady L. Markel and Olga E. Redina
    Citation: BMC Genomics 2016 17(Suppl 14):989
    Content type: Research Published on:

    This article is part of a Supplement: Volume 17 Supplement 14

  33. Progranulin is an epithelial tissue growth factor (also known as proepithelin, acrogranin and PC-cell-derived growth factor) that has been implicated in development, wound healing and in the progression of man...

    Authors: Benoît Cadieux, Babykumari P Chitramuthu, David Baranowski and Hugh PJ Bennett
    Citation: BMC Genomics 2005 6:156
    Content type: Research article Published on:

  34. The differentiation of hematopoietic stem cells into platelet-forming megakaryocytes is of fundamental importance to hemostasis. Constitutive apoptosis is an integral, yet poorly understood, facet of megakaryo...

    Authors: Chi Chen, Peter G Fuhrken, Li Ting Huang, Pani Apostolidis, Min Wang, Carlos J Paredes, William M Miller and Eleftherios T Papoutsakis
    Citation: BMC Genomics 2007 8:384
    Content type: Research article Published on:

  35. Acarbose is used in the treatment of diabetes mellitus type II and is produced by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively studied, profound knowledge about transcript...

    Authors: Timo Wolf, Julian Droste, Tetiana Gren, Vera Ortseifen, Susanne Schneiker-Bekel, Till Zemke, Alfred Pühler and Jörn Kalinowski
    Citation: BMC Genomics 2017 18:562
    Content type: Research article Published on:

  36. Advanced selection technologies have been developed and continually optimized to improve traits of agricultural importance; however, these methods have been primarily applied without knowledge of underlying bi...

    Authors: Nan Zhou, William R Lee and Behnam Abasht
    Citation: BMC Genomics 2015 16:195
    Content type: Research article Published on:

  37. Legionella pneumophila subsp. pneumophila is a gram-negative γ-Proteobacterium and the causative agent of Legionnaires' disease, a form of epidemic pneumonia. It has a water-related life cycle. In industrialized ...

    Authors: Giuseppe D'Auria, Nuria Jiménez-Hernández, Francesc Peris-Bondia, Andrés Moya and Amparo Latorre
    Citation: BMC Genomics 2010 11:181
    Content type: Research article Published on:

  38. Fungal pathogens of plants produce diverse repertoires of secondary metabolites, which have functions ranging from iron acquisition, defense against immune perturbation, to toxic assaults on the host. The whea...

    Authors: Timothy Cairns and Vera Meyer
    Citation: BMC Genomics 2017 18:631
    Content type: Research article Published on:

  39. Adenosine-to-inosine (A-to-I) RNA editing is an epigenetic modification catalyzed by adenosine deaminases acting on RNA (ADARs), and is especially prevalent in the brain. We used the highly accurate microfluid...

    Authors: Hiba Zaidan, Gokul Ramaswami, Yaela N. Golumbic, Noa Sher, Assaf Malik, Michal Barak, Dalia Galiani, Nava Dekel, Jin B. Li and Inna Gaisler-Salomon
    Citation: BMC Genomics 2018 19:28
    Content type: Research article Published on:

  40. Recent work has revealed that a core group of transcription factors (TFs) regulates the key characteristics of embryonic stem (ES) cells: pluripotency and self-renewal. Current efforts focus on identifying gen...

    Authors: Mike J Mason, Guoping Fan, Kathrin Plath, Qing Zhou and Steve Horvath
    Citation: BMC Genomics 2009 10:327
    Content type: Research article Published on:

  41. We evaluated (a) the feasibility of whole genome cDNA-mediated Annealing, Selection, extension and Ligation (DASL) assay on formalin-fixed paraffin-embedded (FFPE) tissue and (b) whether similar conclusions ca...

    Authors: Muhammad G Kibriya, Farzana Jasmine, Shantanu Roy, Rachelle M Paul-Brutus, Maria Argos and Habibul Ahsan
    Citation: BMC Genomics 2010 11:622
    Content type: Research article Published on:

  42. Alfalfa, [Medicago sativa (L.) sativa], a widely-grown perennial forage has potential for development as a cellulosic ethanol feedstock. However, the genomics of alfalfa, a non-model species, is still in its infa...

    Authors: S Samuel Yang, Zheng Jin Tu, Foo Cheung, Wayne Wenzhong Xu, JoAnn FS Lamb, Hans-Joachim G Jung, Carroll P Vance and John W Gronwald
    Citation: BMC Genomics 2011 12:199
    Content type: Research article Published on:

  43. Ophiocordyceps sinensis, a worm and fungus combined mixture which Hirsutella sinensis is parasitic on the caterpillar body, has been used as a traditional medicine or healthy food in China for ...

    Authors: Zhi-Qiang Liu, Shan Lin, Peter James Baker, Ling-Fang Wu, Xiao-Rui Wang, Hui Wu, Feng Xu, Hong-Yan Wang, Mgavi Elombe Brathwaite and Yu-Guo Zheng
    Citation: BMC Genomics 2015 16:106
    Content type: Research article Published on:

  44. Retinol (RO) and its active metabolite retinoic acid (RA) are major regulators of gene expression in vertebrates and influence various processes like organ development, cell differentiation, and immune respons...

    Authors: Clemens Falker-Gieske, Andrea Mott, Sören Franzenburg and Jens Tetens
    Citation: BMC Genomics 2021 22:146
    Content type: Research article Published on:

  45. Drought stress is a prevalent abiotic stress that significantly hinders the growth and development of plants. According to studies, β-aminobutyric acid (BABA) can influence the ABA pathway through the AtIBI1 rece...

    Authors: Cong-Hua Feng, Meng-Xue Niu, Shilei Zhao, Shangjing Guo, Weilun Yin, Xinli Xia and Yanyan Su
    Citation: BMC Genomics 2023 24:473
    Content type: Research Published on:

  46. The acetic acid bacterium Gluconobacter oxydans 621H is characterized by its exceptional ability to incompletely oxidize a great variety of carbohydrates in the periplasm. The metabolism of this α-proteobacterium...

    Authors: Angela Kranz, Tobias Busche, Alexander Vogel, Björn Usadel, Jörn Kalinowski, Michael Bott and Tino Polen
    Citation: BMC Genomics 2018 19:24
    Content type: Research article Published on:

  47. The genus Bordetella consists of nine species that include important respiratory pathogens such as the ‘classical’ species B. bronchiseptica, B. pertussis and B. parapertussis and six more distantly related and l...

    Authors: Bodo Linz, Yury V. Ivanov, Andrew Preston, Lauren Brinkac, Julian Parkhill, Maria Kim, Simon R. Harris, Laura L. Goodfield, Norman K. Fry, Andrew R. Gorringe, Tracy L. Nicholson, Karen B. Register, Liliana Losada and Eric T. Harvill
    Citation: BMC Genomics 2016 17:767
    Content type: Research article Published on:

  48. Synthesis of the Staphylococcus aureus peptidoglycan pentaglycine interpeptide bridge is catalyzed by the nonribosomal peptidyl transferases FemX, FemA and FemB. Inactivation of the femAB operon reduces the inter...

    Authors: Judith Hübscher, Andrea Jansen, Oliver Kotte, Juliane Schäfer, Paul A Majcherczyk, Llinos G Harris, Gabriele Bierbaum, Matthias Heinemann and Brigitte Berger-Bächi
    Citation: BMC Genomics 2007 8:307
    Content type: Research article Published on:

  49. The genetic determinism of blood lipid concentrations, the main risk factor for atherosclerosis, is practically unknown in species other than human and mouse. Even in model organisms, little is known about how...

    Authors: Arianna Manunza, Joaquim Casellas, Raquel Quintanilla, Rayner González-Prendes, Ramona N Pena, Joan Tibau, Anna Mercadé, Anna Castelló, Nitdia Aznárez, Jules Hernández-Sánchez and Marcel Amills
    Citation: BMC Genomics 2014 15:758
    Content type: Research article Published on:

  50. Allele-specific expression (ASE) assays can be used to identify cis, trans, and cis-by-trans regulatory variation. Understanding the source of expression variation has important implications for disease susceptib...

    Authors: Bradley J Main, Ryan D Bickel, Lauren M McIntyre, Rita M Graze, Peter P Calabrese and Sergey V Nuzhdin
    Citation: BMC Genomics 2009 10:422
    Content type: Methodology article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us