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  1. Despite sexual development being ubiquitous to vertebrates, the molecular mechanisms underpinning this fundamental transition remain largely undocumented in many organisms. We designed a time course experiment...

    Authors: Amin R. Mohamed, Marina Naval-Sanchez, Moira Menzies, Bradley Evans, Harry King, Antonio Reverter and James W. Kijas
    Citation: BMC Genomics 2022 23:413
    Content type: Research Published on:

  2. Among the adaptive capacities of animals, the management of energetic body reserves (BR) through the BR mobilization and accretion processes (BR dynamics, BRD) has become an increasingly valuable attribute for...

    Authors: Tiphaine Macé, Eliel González-García, Didier Foulquié, Fabien Carrière, Julien Pradel, Christian Durand, Sebastien Douls, Charlotte Allain, Sara Parisot and Dominique Hazard
    Citation: BMC Genomics 2022 23:412
    Content type: Research Published on:

  3. Catalases (CATs) break down hydrogen peroxide into water and oxygen to prevent cellular oxidative damage, and play key roles in the development, biotic and abiotic stresses of plants. However, the evolutionary re...

    Authors: Luzhao Pan, Yin Luo, Jin Wang, Xiumin Li, Bingqian Tang, Huiping Yang, Xilin Hou, Feng Liu and Xuexiao Zou
    Citation: BMC Genomics 2022 23:411
    Content type: Research Published on:

  4. Tick-borne relapsing fever (TBRF) is a globally prevalent, yet under-studied vector-borne disease transmitted by soft and hard bodied ticks. While soft TBRF (sTBRF) spirochetes have been described for over a c...

    Authors: Alexander R. Kneubehl, Aparna Krishnavajhala, Sebastián Muñoz Leal, Adam J. Replogle, Luke C. Kingry, Sergio E. Bermúdez, Marcelo B. Labruna and Job E. Lopez
    Citation: BMC Genomics 2022 23:410
    Content type: Research Published on:

  5. The yellow catfish, Pelteobagrus fulvidraco, is a commercially important fish species. It is widely distributed in the fresh water areas of China, including rivers, lakes, and reservoirs. Like many other aquacult...

    Authors: Dong Gao, Junrou Huang, Genmei Lin and Jianguo Lu
    Citation: BMC Genomics 2022 23(Suppl 1):409
    Content type: Research Published on:

    This article is part of a Supplement: Volume 23 Supplement 1

  6. Aggression is an evolutionarily conserved behavior critical for animal survival. In the fish Betta splendens, across different stages of fighting interactions, fighting opponents suffer from various stressors, es...

    Authors: Trieu-Duc Vu, Kenshiro Oshima, Kenya Matsumura, Yuki Iwasaki, Ming-Tzu Chiu, Masato Nikaido and Norihiro Okada
    Citation: BMC Genomics 2022 22(Suppl 5):920
    Content type: Research Published on:

    This article is part of a Supplement: Volume 22 Supplement 5

    The Correction to this article has been published in BMC Genomics 2022 23:464

  8. In mammals, the nutritional status experienced during embryonic development shapes key metabolic pathways and influences the health and phenotype of the future individual, a phenomenon known as nutritional pro...

    Authors: Aurélie Sécula, Hervé Chapuis, Anne Collin, Lisa E. Bluy, Agnès Bonnet, Loys Bodin, Laure Gress, Alexis Cornuez, Xavier Martin, Cécile M. D. Bonnefont and Mireille Morisson
    Citation: BMC Genomics 2022 23:407
    Content type: Research Published on:

  9. Non-targeted whole genome sequencing is a powerful tool to comprehensively identify constituents of microbial communities in a sample. There is no need to direct the analysis to any identification before seque...

    Authors: Klaudia Chrzastek, Chandana Tennakoon, Dagmara Bialy, Graham Freimanis, John Flannery and Holly Shelton
    Citation: BMC Genomics 2022 23:406
    Content type: Research Published on:

  10. Tardigrades are microscopic animals that are capable of tolerating extreme environments by entering a desiccated state of suspended animation known as anhydrobiosis. While antioxidative stress proteins, antiap...

    Authors: Yuki Yoshida, Tadashi Satoh, Chise Ota, Sae Tanaka, Daiki D. Horikawa, Masaru Tomita, Koichi Kato and Kazuharu Arakawa
    Citation: BMC Genomics 2022 23:405
    Content type: Research article Published on:

  11. The autoimmune regulator (Aire) gene is critical for the appropriate establishment of central immune tolerance. As one of the main controllers of promiscuous gene expression in the thymus, Aire promotes the ex...

    Authors: Pedro Paranhos Tanaka, Ernna Hérida Oliveira, Mayara Cristina Vieira-Machado, Max Jordan Duarte, Amanda Freire Assis, Karina Fittipaldi Bombonato-Prado and Geraldo Aleixo Passos
    Citation: BMC Genomics 2022 23:404
    Content type: Research Published on:

  12. Peanut (Arachis hypogaea L.) is a grain legume crop that originated from South America and is now grown around the world. Peanut growth habit affects the variety’s adaptability, planting patterns, mechanized harv...

    Authors: Li Li, Shunli Cui, Phat Dang, Xinlei Yang, Xuejun Wei, Kai Chen, Lifeng Liu and Charles Y. Chen
    Citation: BMC Genomics 2022 23:403
    Content type: Research Published on:

  13. CRISPR-Cas9 screening libraries have arisen as a powerful tool to identify protein-coding (pc) and non-coding genes playing a role along different processes. In particular, the usage of a nuclease active Cas9 ...

    Authors: Carme Arnan, Sebastian Ullrich, Carlos Pulido-Quetglas, Ramil Nurtdinov, Alexandre Esteban, Joan Blanco-Fernandez, Estel Aparicio-Prat, Rory Johnson, Sílvia Pérez-Lluch and Roderic Guigó
    Citation: BMC Genomics 2022 23:402
    Content type: Research Published on:

  14. With a growing number of loci associated with late-onset (sporadic) Alzheimer’s disease (AD), the polygenic contribution to AD is now well established. The development of polygenic risk score approaches have s...

    Authors: Michael Vacher, Vincent Doré, Tenielle Porter, Lidija Milicic, Victor L. Villemagne, Pierrick Bourgeat, Sam C. Burnham, Timothy Cox, Colin L. Masters, Christopher C. Rowe, Jurgen Fripp, James D. Doecke and Simon M. Laws
    Citation: BMC Genomics 2022 23:401
    Content type: Research Published on:

  15. Berberine (BBR) is an isoquinoline alkaloid found in the Berberis species. It was found to have protected effects in cardiovascular diseases. Here, we investigated the effect the regulatory function of long no...

    Authors: Ye-Chen Han, Hong-Zhi Xie, Bo Lu, Ruo-Lan Xiang, Jing-Yi Li, Hao Qian and Shu-Yang Zhang
    Citation: BMC Genomics 2022 23:400
    Content type: Research Published on:

  16. Gene regulation is critical for proper cellular function. Next-generation sequencing technology has revealed the presence of regulatory networks that regulate gene expression and essential cellular functions. ...

    Authors: Collin B. Merrill, Austin B. Montgomery, Miguel A. Pabon, Andrey A. Shabalin, Aylin R. Rodan and Adrian Rothenfluh
    Citation: BMC Genomics 2022 23:399
    Content type: Research Published on:

  18. Sucrose non-fermenting 1 (SNF1)-associated protein kinase 2 (SnRK2) proteins belong to a relatively small family of plant-specific serine/threonine (Ser/Thr) protein kinases. SnRK2s participate in the abscisic...

    Authors: Zhu Xiao-lin, Wang Bao-qiang and Wei Xiao-hong
    Citation: BMC Genomics 2022 23:397
    Content type: Research Published on:

  19. Since the first description of lumpy skin disease virus (LSDV) in Africa in the 1920’s, it has brazenly spread beyond Africa into the Middle East, Europe and most recently Asia. In 2017 the first atypical LSDV...

    Authors: Alena Krotova, Olga Byadovskaya, Irina Shumilova, Antoinette van Schalkwyk and Alexander Sprygin
    Citation: BMC Genomics 2022 23:396
    Content type: Research Published on:

  22. The rate of protein accretion and growth affect amino acid requirements in young animals. Differences in amino acid metabolism contribute to individual variations in growth rate. This study aimed at determinin...

    Authors: Shahram Niknafs, Marina R. S. Fortes, Sungbo Cho, John L. Black and Eugeni Roura
    Citation: BMC Genomics 2022 23:393
    Content type: Research Published on:

  23. Transcriptome sequencing is an effective tool to reveal the essential genes and pathways underlying countless biotic and abiotic stress adaptation mechanisms. Although severely challenged by diverse environmen...

    Authors: Grace Afumwaa Boamah, Zekun Huang, Yawei Shen, Yisha Lu, Zhixuan Wang, Ying Su, Changan Xu, Xuan Luo, Caihuan Ke and Weiwei You
    Citation: BMC Genomics 2022 23:392
    Content type: Research Published on:

  25. Grain yield is a complex trait that results from interaction between underlying phenotypic traits and climatic, edaphic, and biotic variables. In rice, main culm panicle node number (MCPNN; the node number on ...

    Authors: Darlene L. Sanchez, Stanley Omar PB. Samonte, Jasper Benedict B. Alpuerto, Peyton A. Croaker, Karina Y. Morales, Yubin Yang, Lloyd T. Wilson, Rodante E. Tabien, Zongbu Yan, Michael J. Thomson and Endang M. Septiningsih
    Citation: BMC Genomics 2022 23:390
    Content type: Research Published on:

  26. Among the major transcription factors, SPL plays a crucial role in plant growth, development, and stress response. Foxtail millet (Setaria italica), as a C4 crop, is rich in nutrients and is beneficial to human h...

    Authors: Dili Lai, Yue Fan, Guoxing Xue, Ailing He, Hao Yang, Chunlin He, Yijing Li, Jingjun Ruan, Jun Yan and Jianping Cheng
    Citation: BMC Genomics 2022 23:389
    Content type: Research Published on:

  27. Spodoptera litura is an important polyphagous pest that causes significant damage to the agricultural sector. We performed RNA-seq of 15 S. litura individuals from larval (fifth and sixth instar larvae), chrysali...

    Authors: Ruixiang Tang, Fangyuan Liu, Yue Lan, Jiao Wang, Lei Wang, Jing Li, Xu Liu, Zhenxin Fan, Tao Guo and Bisong Yue
    Citation: BMC Genomics 2022 23:388
    Content type: Research Published on:

  28. Beef cuts in different regions of the carcass have different meat quality due to their distinct physiological function. The objective of this study was to characterize the region-specific expression difference...

    Authors: Tianliu Zhang, Tianzhen Wang, Qunhao Niu, Xu Zheng, Haipeng Li, Xue Gao, Yan Chen, Huijiang Gao, Lupei Zhang, George E. Liu, Junya Li and Lingyang Xu
    Citation: BMC Genomics 2022 23:387
    Content type: Research Published on:

  29. High yield and quality are essential goals of wheat (Triticum aestivum L.) breeding. Kernel length (KL), as a main component of kernel size, can indirectly change kernel weight and then affects yield. Identificat...

    Authors: Xinlin Xie, Shuiqin Li, Hang Liu, Qiang Xu, Huaping Tang, Yang Mu, Mei Deng, Qiantao Jiang, Guoyue Chen, Pengfei Qi, Wei Li, Zhien Pu, Ahsan Habib, Yuming Wei, Youliang Zheng, Xiujin Lan…
    Citation: BMC Genomics 2022 23:386
    Content type: Research Published on:

  30. As genomic sequencing moves closer to clinical implementation, there has been an increasing acceptance of returning incidental findings to research participants and patients for mutations in highly penetrant, ...

    Authors: Yen-Chen A. Feng, Ian B. Stanaway, John J. Connolly, Joshua C. Denny, Yuan Luo, Chunhua Weng, Wei-Qi Wei, Scott T. Weiss, Elizabeth W. Karlson and Jordan W. Smoller
    Citation: BMC Genomics 2022 23:385
    Content type: Research Published on:

  32. Cucumber is an important melon crop in the world, with different pericarp colors. However, the candidate genes and the underlying genetic mechanism for such an important trait in cucumber are unknown. In this ...

    Authors: Hongyu Huang, Qinqin Yang, Lidong Zhang, Weiliang Kong, Huizhe Wang, Aimin Wei, Shengli Du, Ruihuan Yang, Jiawang Li, Tao Lin, Xiaolin Geng and Yuhe Li
    Citation: BMC Genomics 2022 23:383
    Content type: Research Published on:

  33. Tolerance of low temperature has a significant impact on survival and expansion of invasive snail Pomacea canalicuata. Cold acclimation can enhance cold tolerance of Pomacea canalicuata. To elucidate the molecula...

    Authors: Qi Xiao, Youfu Lin, Hong Li, Yu Chen, Wei Wei, Peng Li and Lian Chen
    Citation: BMC Genomics 2022 23:382
    Content type: Research Published on:

  34. Previous studies on plant long noncoding RNAs (lncRNAs) lacked consistency and suffered from many factors like heterogeneous data sources and experimental protocols, different plant tissues, inconsistent bioin...

    Authors: Yan Zhu, Longxian Chen, Xiangna Hong, Han Shi and Xuan Li
    Citation: BMC Genomics 2022 23(Suppl 4):381
    Content type: Research Published on:

    This article is part of a Supplement: Volume 23 Supplement 4

  35. Drug-resistant bacteria have posed a great threat to animal breeding and human health. It is obviously urgent to develop new antibiotics that can effectively combat drug-resistant bacteria. The commensal flora...

    Authors: Ke Ma, Wei Chen, Shi-Qing Yan, Xiao-Qi Lin, Zhen-Zhen Liu, Jia-Bao Zhang, Yu Gao and Yong-Jun Yang
    Citation: BMC Genomics 2022 23:380
    Content type: Research Published on:

  36. Despite a multifactorial approach being taken for the evaluation of bull semen quality in many animal breeding centres worldwide, reliable prediction of bull fertility is still a challenge. Recently, attention...

    Authors: Miriama Štiavnická, Aurélie Chaulot-Talmon, Jean-Philippe Perrier, Petr Hošek, David A. Kenny, Patrick Lonergan, Hélène Kiefer and Sean Fair
    Citation: BMC Genomics 2022 23:379
    Content type: Research Published on:

  37. Oysters inhabit in the intertidal zone and may be suffered from environmental stresses, which can increase the production of reactive oxygen species (ROS), resulting in mass mortality. Superoxide dismutases (S...

    Authors: Youli Liu, Zhenmin Bao, Zhihua Lin and Qinggang Xue
    Citation: BMC Genomics 2022 23:378
    Content type: Research Published on:

  39. Within the class Enoplea, the earliest-branching lineages in the phylum Nematoda, the relatively highly conserved ancestral mitochondrial architecture of Trichinellida is in stark contrast to the rapidly evolv...

    Authors: Hong Zou, Fang-Lin Chen, Wen-Xiang Li, Ming Li, Hong-Peng Lei, Dong Zhang, Ivan Jakovlić and Gui-Tang Wang
    Citation: BMC Genomics 2022 23:376
    Content type: Research Published on:

  40. While the genus Variovorax is known for its aromatic compound metabolism, no detailed study of the peripheral and central pathways of aromatic compound degradation has yet been reported. Variovorax sp. PAMC26660 ...

    Authors: Nisha Ghimire, Byeollee Kim, Chang-Muk Lee and Tae-Jin Oh
    Citation: BMC Genomics 2022 23:375
    Content type: Research Published on:

  41. CIRCADIAN CLOCK ASSOCIATED 1 like (CCA1L) proteins are important components that participate in plant growth and development, and now have been characterized in multiple plant species. However, information on ...

    Authors: Chenyang Liu, Qianqian Zhang, Jing Dong, Chunmei Cai, Hong Zhu and Shuai Li
    Citation: BMC Genomics 2022 23:374
    Content type: Research Published on:

  42. Runs of homozygosity (ROH) are continuous homozygous regions typically located in the DNA sequence of diploid organisms. Identifications of ROH that lead to reduced performance can provide valuable insight int...

    Authors: Yao Jiang, Xiaojin Li, Jiali Liu, Wei Zhang, Mei Zhou, Jieru Wang, Linqing Liu, Shiguang Su, Fuping Zhao, Hongquan Chen and Chonglong Wang
    Citation: BMC Genomics 2022 23:373
    Content type: Research Published on:

  43. Septoria tritici blotch (STB), caused by Zymoseptoria tritici (Z. tritici), is an important biotic threat to durum wheat in the entire Mediterranean Basin. Although most durum wheat cultivars are susceptible to Z...

    Authors: Sahbi Ferjaoui, Lamia Aouini, Rim B. Slimane, Karim Ammar, Suzanne Dreisigacker, Henk J. Schouten, Suraj Sapkota, Bochra A. Bahri, Sarrah Ben M’Barek, Richard G. F. Visser, Gert H. J. Kema and Sonia Hamza
    Citation: BMC Genomics 2022 23:372
    Content type: Research Published on:

  44. Cucurbita pepo is highly susceptible to Zucchini yellow mosaic virus (ZYMV) and the resistance found in several wild species cannot be considered as complete or broad-spectrum resistance. In this study, a source ...

    Authors: C. G. Amoroso, G. Andolfo, C. Capuozzo, A. Di Donato, C. Martinez, L. Tomassoli and M. R. Ercolano
    Citation: BMC Genomics 2022 23:371
    Content type: Research Published on:

  45. Authors: Yulin Bai, Mei Wang, Ji Zhao, Huaqiang Bai, Xinyi Zhang, Jiaying Wang, Qiaozhen Ke, Ang Qu, Fei Pu, Weiqiang Zheng, Tao Zhou and Peng Xu
    Citation: BMC Genomics 2022 23:370
    Content type: Correction Published on:

    The original article was published in BMC Genomics 2022 23:206

  46. Drought stress is the most limiting factor for plant growth and crop production worldwide. As a major cereal crop, wheat is susceptible to drought. Thus, discovering and utilizing drought-tolerant gene resourc...

    Authors: Fengkun Lu, Wenjing Duan, Yue Cui, Junwei Zhang, Dong Zhu, Ming Zhang and Yueming Yan
    Citation: BMC Genomics 2022 23:369
    Content type: Research Published on:

  47. Numerous genome-wide association studies have been performed to understand the influence of genetic variation on type 2 diabetes etiology. Many identified risk variants are located in non-coding and intergenic...

    Authors: Gerard A. Bouland, Joline W. J. Beulens, Joey Nap, Arno R. van der Slik, Arnaud Zaldumbide, Leen M. ’t Hart and Roderick C. Slieker
    Citation: BMC Genomics 2022 23:368
    Content type: Research Published on:

  48. Baculoviruses act as effective biological control agents against the invasive pest Hyphantria cunea Drury. In this study, two Chinese Hyphantria cunea nucleopolyhedrovirus (HycuNPV) isolates, HycuNPV-BJ and HycuN...

    Authors: Xiaowei Peng, Wenying Zhang, Chengfeng Lei, Shuifa Min, Jia Hu, Qinghua Wang and Xiulian Sun
    Citation: BMC Genomics 2022 23:367
    Content type: Research Published on:

  49. Pichia pastoris (Komagataella phaffii) is a model organism widely used for the recombinant expression of eukaryotic proteins, and it can metabolize methanol as its sole carbon and energy source. Methanol is oxidi...

    Authors: Yi-fan Yu, Jiashuo Yang, Fengguang Zhao, Ying Lin and Shuangyan Han
    Citation: BMC Genomics 2022 23:366
    Content type: Research Published on:

  50. Escherichia coli carrying clinically important antimicrobial resistances [i.e., against extended-spectrum-beta-lactamases (ESBL)] are of high concern for human health and are increasingly detected worldwide. Worr...

    Authors: Katharina Juraschek, Janina Malekzadah, Burkhard Malorny, Annemarie Käsbohrer, Stefan Schwarz, Diana Meemken and Jens Andre Hammerl
    Citation: BMC Genomics 2022 23:365
    Content type: Research Published on:

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BMC Genomics

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