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  1. Age-related resistance (ARR) is a developmentally regulated phenomenon conferring resistance to pathogens or pests. Although ARR has been observed in several host-pathogen systems, the underlying mechanisms ar...

    Authors: Ben N. Mansfeld, Marivi Colle, Chunqiu Zhang, Ying-Chen Lin and Rebecca Grumet

    Citation: BMC Genomics 2020 21:628

    Content type: Research article

    Published on:

  2. The environmental impact of pig farming need to be reduced, with phosphorus (P) being of particular interest. Specified dietary regimens and management systems contribute to meet environmental concerns and red...

    Authors: Aisanjiang Wubuli, Christian Gerlinger, Henry Reyer, Michael Oster, Eduard Muráni, Nares Trakooljul, Siriluck Ponsuksili, Petra Wolf and Klaus Wimmers

    Citation: BMC Genomics 2020 21:626

    Content type: Research article

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  3. Goats (Capra hircus), one of the first domesticated species, are economically important for milk and meat production, and their broad geographical distribution reflects their successful adaptation to diverse envi...

    Authors: Francesco Giannico, Serafina Massari, Anna Caputi Jambrenghi, Adriano Soriano, Angela Pala, Giovanna Linguiti, Salvatrice Ciccarese and Rachele Antonacci

    Citation: BMC Genomics 2020 21:623

    Content type: Research article

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  4. Chrysosplenium L. (Saxifragaceae) is a genus of plants widely distributed in Northern Hemisphere and usually found in moist, shaded valleys and mountain slopes. This genus is ideal for studying plant adaptation t...

    Authors: Zhihua Wu, Rui Liao, Tiange Yang, Xiang Dong, Deqing Lan, Rui Qin and Hong Liu

    Citation: BMC Genomics 2020 21:621

    Content type: Research article

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  5. Since 2008, the aquaculture production of Crassostrea gigas was heavily affected by mass mortalities associated to Ostreid herpesvirus 1 (OsHV-1) microvariants worldwide. Transcriptomic studies revealed the major...

    Authors: Umberto Rosani, Miriam Abbadi, Timothy Green, Chang-Ming Bai, Edoardo Turolla, Giuseppe Arcangeli, K. Mathias Wegner and Paola Venier

    Citation: BMC Genomics 2020 21:620

    Content type: Research article

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  6. Chimpanzees are the closest living relatives of humans. The divergence between human and chimpanzee ancestors dates to approximately 6,5–7,5 million years ago. Genetic features distinguishing us from chimpanze...

    Authors: Maria V. Suntsova and Anton A. Buzdin

    Citation: BMC Genomics 2020 21(Suppl 7):535

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  7. Massive forest decline has been observed almost everywhere as a result of negative anthropogenic and climatic effects, which can interact with pests, fungi and other phytopathogens and aggravate their effects....

    Authors: Vasilina S. Akulova, Vadim V. Sharov, Anastasiya I. Aksyonova, Yuliya A. Putintseva, Natalya V. Oreshkova, Sergey I. Feranchuk, Dmitry A. Kuzmin, Igor N. Pavlov, Yulia A. Litovka and Konstantin V. Krutovsky

    Citation: BMC Genomics 2020 21(Suppl 7):534

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  8. Head-to-head comparison of BeadChip and WGS/WES genotyping techniques for their precision is far from straightforward. A tool for validation of high-throughput genotyping calls such as Sanger sequencing is nei...

    Authors: Kirill A. Danilov, Dimitri A. Nikogosov, Sergey V. Musienko and Ancha V. Baranova

    Citation: BMC Genomics 2020 21(Suppl 7):528

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  9. Predicting the eye and hair color from genotype became an established and widely used tool in forensic genetics, as well as in studies of ancient human populations. However, the accuracy of this tool has been ...

    Authors: Elena Balanovska, Elena Lukianova, Janet Kagazezheva, Andrey Maurer, Natalia Leybova, Anastasiya Agdzhoyan, Igor Gorin, Valeria Petrushenko, Maxat Zhabagin, Vladimir Pylev, Elena Kostryukova and Oleg Balanovsky

    Citation: BMC Genomics 2020 21(Suppl 7):527

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  10. According to history, in the pre-Hispanic period, during the conquest and Inka expansion in Ecuador, many Andean families of the Cañar region would have been displaced to several places of Tawantinsuyu, including...

    Authors: José R. Sandoval, Daniela R. Lacerda, Marilza M. S. Jota, Paulo Robles-Ruiz, Pierina Danos, César Paz-y-Miño, Spencer Wells, Fabrício R. Santos and Ricardo Fujita

    Citation: BMC Genomics 2020 21(Suppl 7):413

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  11. Background Telomeres, which are composed of repetitive nucleotide sequences at the end of chromosomes, behave as a division clock that measures replicative senescence. Under the normal physiological condition,...

    Authors: Kyung Hyun Lee and Marek Kimmel

    Citation: BMC Genomics 2020 21(Suppl 9):587

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  12. Haplotypes, the ordered lists of single nucleotide variations that distinguish chromosomal sequences from their homologous pairs, may reveal an individual’s susceptibility to hereditary and complex diseases an...

    Authors: Abishek Sankararaman, Haris Vikalo and François Baccelli

    Citation: BMC Genomics 2020 21(Suppl 9):586

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  13. Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the u...

    Authors: Siamak Zamani Dadaneh, Paul de Figueiredo, Sing-Hoi Sze, Mingyuan Zhou and Xiaoning Qian

    Citation: BMC Genomics 2020 21(Suppl 9):585

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  14. B cell affinity maturation enables B cells to generate high-affinity antibodies. This process involves somatic hypermutation of B cell immunoglobulin receptor (BCR) genes and selection by their ability to bind...

    Authors: Xingyu Yang, Christopher M. Tipton, Matthew C. Woodruff, Enlu Zhou, F. Eun-Hyung Lee, Inãki Sanz and Peng Qiu

    Citation: BMC Genomics 2020 21(Suppl 9):583

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  15. Mitogen Activated Protein Kinase (MAPK) cascade is a fundamental pathway in organisms for signal transduction. Though it is well characterized in various plants, there is no systematic study of this cascade in...

    Authors: Archita Chatterjee, Abhirup Paul, G. Meher Unnati, Ruchika Rajput, Trisha Biswas, Tamalika Kar, Srijita Basak, Neelam Mishra, Ashutosh Pandey and Anurag Prakash Srivastava

    Citation: BMC Genomics 2020 21:613

    Content type: Research article

    Published on:

  16. Lysin motif-containing proteins (LYP), which act as pattern-recognition receptors, play central roles in growth, node formation, and responses to biotic stresses. The sequence of Chinese white pear genome (cv....

    Authors: Qiming Chen, Qionghou Li, Xin Qiao, Hao Yin and Shaoling Zhang

    Citation: BMC Genomics 2020 21:612

    Content type: Research article

    Published on:

  17. Anthocyanins determinate the flower color of many plants. Tobacco is a model plant for studying the molecular regulation of flower coloration. We investigated the mechanism underlying flower coloration in toba...

    Authors: Fangchan Jiao, Lu Zhao, Xingfu Wu, Zhongbang Song and Yongping Li

    Citation: BMC Genomics 2020 21:611

    Content type: Research article

    Published on:

  18. Phytohormones are the key factors regulating vascular development in plants, and they are also involved in tension wood (TW) formation. Although the theory of hormone distribution in TW formation is widely sup...

    Authors: Yao Xiao, Fei Yi, Juanjuan Ling, Guijuan Yang, Na Lu, Zirui Jia, Junchen Wang, Kun Zhao, Junhui Wang and Wenjun Ma

    Citation: BMC Genomics 2020 21:609

    Content type: Research article

    Published on:

  19. Sand flies are the vectors of Leishmania parasites. To develop in the sand fly midgut, Leishmania multiplies and undergoes various stage differentiations giving rise to the infective form, the metacyclic promasti...

    Authors: Iliano V. Coutinho-Abreu, Tiago Donatelli Serafim, Claudio Meneses, Shaden Kamhawi, Fabiano Oliveira and Jesus G. Valenzuela

    Citation: BMC Genomics 2020 21:608

    Content type: Research article

    Published on:

  20. Argeia pugettensis is an isopod species that parasitizes other crustaceans. Its huge native geographic range spans the Pacific from China to California, but molecular data are available only for a handful of spec...

    Authors: Jianmei An, Wanrui Zheng, Jielong Liang, Qianqian Xi, Ruru Chen, Junli Jia, Xia Lu and Ivan Jakovlić

    Citation: BMC Genomics 2020 21:607

    Content type: Research article

    Published on:

  21. Immune-response (IR) genes have an important role in the defense against highly variable pathogens, and therefore, diversity in these genomic regions is essential for species’ survival and adaptation. Although...

    Authors: Sara Lado, Jean P. Elbers, Mark F. Rogers, José Melo-Ferreira, Adiya Yadamsuren, Jukka Corander, Petr Horin and Pamela A. Burger

    Citation: BMC Genomics 2020 21:606

    Content type: Research article

    Published on:

  22. Phenotypic performances of livestock animals decline with increasing levels of inbreeding, however, the noticeable decline known as inbreeding depression, may not be due only to the total level of inbreeding, ...

    Authors: Bayode O. Makanjuola, Christian Maltecca, Filippo Miglior, Flavio S. Schenkel and Christine F. Baes

    Citation: BMC Genomics 2020 21:605

    Content type: Research article

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  23. Aedes aegypti is the principle vector of many arboviruses, including dengue virus and Zika virus, which are transmitted when an infected female mosquito takes a blood meal in order to initiate vitellogenesis. Dur...

    Authors: Heather Eggleston and Zach N. Adelman

    Citation: BMC Genomics 2020 21:604

    Content type: Research article

    Published on:

  24. Seed germination and young seedling growth are important agricultural traits for developing populations of both irrigated and directly seeded rice. Previous studies have focused on the identification of QTLs. ...

    Authors: Jing Yang, Ling Su, Dandan Li, Lixin Luo, Kai Sun, Meng Yang, Fengwei Gu, Aoyun Xia, Yongzhu Liu, Hui Wang, Zhiqiang Chen and Tao Guo

    Citation: BMC Genomics 2020 21:603

    Content type: Research article

    Published on:

  25. The WD40-repeat containing proteins, including DDB1–CUL4-associated factors (DCAFs), are abundant and conserved proteins that play important roles in different cellular processes including spermatogenesis. DCA...

    Authors: Bhavesh V. Mistry, Maha Alanazi, Hanae Fitwi, Olfat Al-Harazi, Mohamed Rajab, Abdullah Altorbag, Falah Almohanna, Dilek Colak and Abdullah M. Assiri

    Citation: BMC Genomics 2020 21:602

    Content type: Research article

    Published on:

  26. It has been reported that nitric oxide (NO) could ameliorate cadmium (Cd) toxicity in tall fescue; however, the underlying mechanisms of NO mediated Cd detoxification are largely unknown. In this study, we inv...

    Authors: Huihui Zhu, Honglian Ai, Zhengrong Hu, Dongyun Du, Jie Sun, Ke Chen and Liang Chen

    Citation: BMC Genomics 2020 21:601

    Content type: Research article

    Published on:

  27. Long non-coding RNAs (lncRNAs) are involved in many fundamental biological processes, such as transcription regulation, protein degradation, and cell differentiation. Information on lncRNA in the melon fly, Zeugo...

    Authors: Wei-Jun Li, Yu-Jia Song, Hong-Liang Han, Hui-Qian Xu, Dong Wei, Guy Smagghe and Jin-Jun Wang

    Citation: BMC Genomics 2020 21:600

    Content type: Research article

    Published on:

  28. Vibriosis has been implicated in major losses of larvae at shellfish hatcheries. However, the species of Vibrio responsible for disease in aquaculture settings and their associated virulence genes are often varia...

    Authors: Hanna Kehlet-Delgado, Claudia C. Häse and Ryan S. Mueller

    Citation: BMC Genomics 2020 21:599

    Content type: Research article

    Published on:

  29. Most animals restrict their activity to a specific part of the day, being diurnal, nocturnal or crepuscular. The genetic basis underlying diurnal preference is largely unknown. Under laboratory conditions, Drosop...

    Authors: Mirko Pegoraro, Laura M. M. Flavell, Pamela Menegazzi, Perrine Colombi, Pauline Dao, Charlotte Helfrich-Förster and Eran Tauber

    Citation: BMC Genomics 2020 21:596

    Content type: Research article

    Published on:

  30. Genomic comparison of Mycoplasma synoviae vaccine strain MS-H and the MS-H parental strain 86,079/7NS established a preliminary profile of genes related to attenuation of MS-H. In this study we aimed to identify ...

    Authors: Somayeh Kordafshari, Pollob Shil, Marc S. Marenda, Olusola M. Olaogun, Barbara Konsak-Ilievski, Jillian Disint and Amir H. Noormohammadi

    Citation: BMC Genomics 2020 21:598

    Content type: Research article

    Published on:

  31. Antimicrobial resistance is one of our most serious health threats. Antimicrobial peptides (AMPs), effecter molecules of innate immune system, can defend host organisms against microbes and most have shown a l...

    Authors: Haoyi Fu, Zicheng Cao, Mingyuan Li and Shunfang Wang

    Citation: BMC Genomics 2020 21:597

    Content type: Research article

    Published on:

  32. Feather pecking (FP) in laying hens reduces animal welfare and leads to economic losses for the layer industry. FP is considered a heritable condition that is influenced by dysregulation of neurotransmitter ho...

    Authors: Clemens Falker-Gieske, Andrea Mott, Siegfried Preuß, Sören Franzenburg, Werner Bessei, Jörn Bennewitz and Jens Tetens

    Citation: BMC Genomics 2020 21:595

    Content type: Research article

    Published on:

  33. The Quaternary had worldwide consequences in forming the contemporary diversity of many populations, species and communities, which is characterized by marked climatic oscillations between glacial and intergla...

    Authors: Kai Song, Bin Gao, Peter Halvarsson, Yun Fang, Ying-Xin Jiang, Yue-Hua Sun and Jacob Höglund

    Citation: BMC Genomics 2020 21:581

    Content type: Research article

    Published on:

  34. Tissue-specific fat deposition is regulated by a series of complex regulatory mechanisms. Reports indicate that epigenetic regulators, such as circular RNAs (circRNAs), are crucial in diseases progression, ani...

    Authors: Meng Zhang, Yu Han, Yanhui Zhai, Xiangfei Ma, Xinglan An, Sheng Zhang and Ziyi Li

    Citation: BMC Genomics 2020 21:594

    Content type: Research article

    Published on:

  35. Duplications of large genomic segments provide genetic diversity in genome evolution. Despite their importance, how these duplications are generated remains uncertain, particularly for distant duplicated genom...

    Authors: Javier U. Chicote, Marcos López-Sánchez, Tomàs Marquès-Bonet, José Callizo, Luis A. Pérez-Jurado and Antonio García-España

    Citation: BMC Genomics 2020 21:593

    Content type: Research article

    Published on:

  36. The DGAT1 gene encodes an enzyme responsible for catalysing the terminal reaction in mammary triglyceride synthesis, and underpins a well-known pleiotropic quantitative trait locus (QTL) with a large influence on...

    Authors: Tania Fink, Thomas J. Lopdell, Kathryn Tiplady, Renee Handley, Thomas J. J. Johnson, Richard J. Spelman, Stephen R. Davis, Russell G. Snell and Mathew D. Littlejohn

    Citation: BMC Genomics 2020 21:591

    Content type: Research article

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  37. Prolonged exposure to elevated free fatty acids induces β-cell failure (lipotoxicity) and contributes to the pathogenesis of type 2 diabetes. In vitro exposure of β-cells to the saturated free fatty acid palmi...

    Authors: Maria Lytrivi, Kassem Ghaddar, Miguel Lopes, Victoria Rosengren, Anthony Piron, Xiaoyan Yi, Henrik Johansson, Janne Lehtiö, Mariana Igoillo-Esteve, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Henrik Ortsäter, Decio L. Eizirik and Miriam Cnop

    Citation: BMC Genomics 2020 21:590

    Content type: Research article

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  38. More than 2500 species belong to the Meloidae family (Coleoptera: Tenebrionoidea), members of which produce the potent defensive blistering agent cantharidin and are commonly known as blister beetles or Spanishfl...

    Authors: Yuan-Ming Wu, Yang-Yang Liu and Xiang-Sheng Chen

    Citation: BMC Genomics 2020 21:589

    Content type: Research article

    Published on:

  39. Antagonistic co-evolution can drive rapid adaptation in pathogens and shape genome architecture. Comparative genome analyses of several fungal pathogens revealed highly variable genomes, for many species chara...

    Authors: Alice Feurtey, Cécile Lorrain, Daniel Croll, Christoph Eschenbrenner, Michael Freitag, Michael Habig, Janine Haueisen, Mareike Möller, Klaas Schotanus and Eva H. Stukenbrock

    Citation: BMC Genomics 2020 21:588

    Content type: Research article

    Published on:

  40. Alternative splicing (AS) offers a main mechanism to form protein polymorphism. A growing body of evidence indicates the correlation between splicing disorders and carcinoma. Nevertheless, an overall analysis ...

    Authors: Yuanyuan Zhang, Shengling Ma, Qian Niu, Yun Han, Xingyu Liu, Jie Jiang, Simiao Chen and Haolong Lin

    Citation: BMC Genomics 2020 21:580

    Content type: Research article

    Published on:

  41. Drought is one of the most adverse environmental factors limiting crop productions and it is important to identify key genetic determinants for food safety. Calcium-dependent protein kinases (CPKs) are known t...

    Authors: Ge-Zi Li, Han-Xiao Li, Meng-Jun Xu, Peng-Fei Wang, Xiang-Hong Xiao and Guo-Zhang Kang

    Citation: BMC Genomics 2020 21:577

    Content type: Research article

    Published on:

  42. A balanced constitutional reciprocal translocation (RT) is a mutual exchange of terminal segments of two non-homologous chromosomes without any loss or gain of DNA in germline cells. Carriers of balanced RTs a...

    Authors: Aniek C. Bouwman, Martijn F. L. Derks, Marleen L. W. J. Broekhuijse, Barbara Harlizius and Roel F. Veerkamp

    Citation: BMC Genomics 2020 21:576

    Content type: Research article

    Published on:

  43. Cotton (Gossypium spp.) is the most important world-wide fiber crop but salt stress limits cotton production in coastal and other areas. Growth regulation factors (GRFs) play regulatory roles in response to salt ...

    Authors: Jun-Feng Cao, Jin-Quan Huang, Xia Liu, Chao-Chen Huang, Zi-Shou Zheng, Xiu-Fang Zhang, Xiao-Xia Shangguan, Ling-Jian Wang, Yu-Gao Zhang, Jonathan F. Wendel, Corrinne E. Grover and Zhi-Wen Chen

    Citation: BMC Genomics 2020 21:575

    Content type: Research article

    Published on:

  44. Blue mold is a globally important and economically impactful postharvest disease of apples caused by multiple Penicillium spp. There are currently four postharvest fungicides registered for blue mold control, and...

    Authors: Franz J. Lichtner, Verneta L. Gaskins, Kerik D. Cox and Wayne M. Jurick II

    Citation: BMC Genomics 2020 21:574

    Content type: Research article

    Published on:

  45. ERF transcription factors (TFs) belong to the Apetala2/Ethylene responsive Factor (AP2/ERF) TF family and play a vital role in plant growth and development processes. Capsorubin and capsaicinoids have relative...

    Authors: Jiali Song, Changming Chen, Shuanglin Zhang, Juntao Wang, Zhubing Huang, Muxi Chen, Bihao Cao, Zhangsheng Zhu and Jianjun Lei

    Citation: BMC Genomics 2020 21:573

    Content type: Research article

    Published on:

  46. As air temperatures increase globally, more and more plants are exposed to heat-stress conditions. Although many studies have explored regulation networks in plants with the aim of improving their heat-stress ...

    Authors: Jiahong Xu, Yao Zheng, Shouqin Pu, Xiujie Zhang, Zhihao Li and Jinhui Chen

    Citation: BMC Genomics 2020 21:572

    Content type: Research article

    Published on:

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