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  1. The pistil is an essential part of flowers that functions in the differentiation of the sexes and reproduction in plants. The stigma on the pistil can accept pollen to allow fertilization and seed development....

    Authors: Zhenyang Liao, Fei Dong, Juan Liu, Lele Xu, Amy Marshall-Colon and Ray Ming

    Citation: BMC Genomics 2022 23:8

    Content type: Research

    Published on:

  2. In the nematode Caenorhabditis elegans, longevity in response to germline ablation, but not in response to reduced insulin/IGF1-like signaling, is strongly dependent on the conserved protein kinase minibrain-rela...

    Authors: Hildegard I. D. Mack, Jennifer Kremer, Eva Albertini, Elisabeth K. M. Mack and Pidder Jansen-Dürr

    Citation: BMC Genomics 2022 23:25

    Content type: Research

    Published on:

  3. Authors: Sofa A. Bengoa Luoni, Alberto Cenci, Sebastian Moschen, Salvador Nicosia, Laura M. Radonic, Julia V. Sabio y García, Nicolas B. Langlade, Denis Vile, Cecilia Vazquez Rovere and Paula Fernandez

    Citation: BMC Genomics 2022 23:24

    Content type: Correction

    Published on:

    The original article was published in BMC Genomics 2021 22:893

  4. South Africa and Australia shares multiple important sheep breeds. For some of these breeds, genomic breeding values are provided to breeders in Australia, but not yet in South Africa. Combining genomic resour...

    Authors: Cornelius Nel, Phillip Gurman, Andrew Swan, Julius van der Werf, Margaretha Snyman, Kennedy Dzama, Klint Gore, Anna Scholtz and Schalk Cloete

    Citation: BMC Genomics 2022 23:23

    Content type: Research

    Published on:

  5. Circular RNAs (circRNAs) are a group of noncoding RNAs that participate in gene expression regulation in various pathways. The essential roles of circRNAs have been revealed in many species. However, knowledge...

    Authors: Xingwei Cao, Xingye Xu, Jie Dong, Ying Xue, Lilian Sun, Yafang Zhu, Tao Liu and Qi Jin

    Citation: BMC Genomics 2022 23:21

    Content type: Research

    Published on:

  6. Transposable elements (TE) make up a large portion of many plant genomes and are playing innovative roles in genome evolution. Several TEs can contribute to gene regulation by influencing expression of nearby ...

    Authors: Jan Deneweth, Yves Van de Peer and Vanessa Vermeirssen

    Citation: BMC Genomics 2022 23:18

    Content type: Research

    Published on:

  7. Sexual maturation causes loss of fish muscle mass and deterioration of fillet quality attributes that prevent market success. We recently showed that fillet yield and flesh quality recover in female trout afte...

    Authors: Yéléhi-Diane Ahongo, Aurélie Le Cam, Jérôme Montfort, Jérôme Bugeon, Florence Lefèvre and Pierre-Yves Rescan

    Citation: BMC Genomics 2022 23:9

    Content type: Research

    Published on:

  8. With the exponential growth of publicly available genome sequences, pangenome analyses have provided increasingly complete pictures of genetic diversity for many microbial species. However, relatively few stud...

    Authors: Jason C. Hyun, Jonathan M. Monk and Bernhard O. Palsson

    Citation: BMC Genomics 2022 23:7

    Content type: Research

    Published on:

  9. Snakes exhibit extreme intestinal regeneration following months-long fasts that involves unparalleled increases in metabolism, function, and tissue growth, but the specific molecular control of this process is...

    Authors: Aundrea K. Westfall, Blair W. Perry, Abu H. M. Kamal, Nicole R. Hales, Jarren C. Kay, Madhab Sapkota, Drew R. Schield, Mark W. Pellegrino, Stephen M. Secor, Saiful M. Chowdhury and Todd A. Castoe

    Citation: BMC Genomics 2022 23:6

    Content type: Research article

    Published on:

  10. Grain size is a key factor in crop yield that gradually develops after pollination. However, few studies have reported gene expression patterns in maize grain development using large-grain mutants. To investig...

    Authors: Yanrong Zhang, Fuchao Jiao, Jun Li, Yuhe Pei, Meiai Zhao, Xiyun Song and Xinmei Guo

    Citation: BMC Genomics 2022 23:4

    Content type: Research

    Published on:

  11. Because some of its CNS neurons (e.g., retinal ganglion cells after optic nerve crush (ONC)) regenerate axons throughout life, whereas others (e.g., hindbrain neurons after spinal cord injury (SCI)) lose this cap...

    Authors: Sergei Reverdatto, Aparna Prasad, Jamie L. Belrose, Xiang Zhang, Morgan A. Sammons, Kurt M. Gibbs and Ben G. Szaro

    Citation: BMC Genomics 2022 23:2

    Content type: Research

    Published on:

  12. The mechanism implicated in the osteogenesis of human periodontal ligament stem cells (PDLSCs) has been investigated for years. Previous genomics data analyses showed that long noncoding RNA (lncRNA), microRNA...

    Authors: Lingzhi Lai, Zhaodan Wang, Yihong Ge, Wei Qiu, Buling Wu, Fuchun Fang, Huiyong Xu and Zhao Chen

    Citation: BMC Genomics 2022 23:1

    Content type: Research

    Published on:

  13. SPX-containing proteins have been known as key players in phosphate signaling and homeostasis. In Arabidopsis and rice, functions of some SPXs have been characterized, but little is known about their function ...

    Authors: Mahnaz Nezamivand-Chegini, Esmaeil Ebrahimie, Ahmad Tahmasebi, Ali Moghadam, Saeid Eshghi, Manijeh Mohammadi-Dehchesmeh, Stanislav Kopriva and Ali Niazi

    Citation: BMC Genomics 2021 22:915

    Content type: Research

    Published on:

  14. The yield of many crop plants can be substantially reduced by plant-pathogenic Xanthomonas bacteria. The infection strategy of many Xanthomonas strains is based on transcription activator-like effectors (TALEs), ...

    Authors: Annett Erkes, Stefanie Mücke, Maik Reschke, Jens Boch and Jan Grau

    Citation: BMC Genomics 2021 22:914

    Content type: Research

    Published on:

  15. The severity of influenza disease can range from mild symptoms to severe respiratory failure and can partly be explained by host genetic factors that predisposes the host to severe influenza. Here, we aimed to...

    Authors: Nina Van Goethem, Célestin Danwang, Nathalie Bossuyt, Herman Van Oyen, Nancy H. C. Roosens and Annie Robert

    Citation: BMC Genomics 2021 22:912

    Content type: Research article

    Published on:

  16. Known as the prerequisite component for the heterosis breeding system, the male sterile line determines the hybrid yield and seed purity. Therefore, a deep understanding of the mechanism and gene network that ...

    Authors: Yong-jie Liu, Dan Li, Jie Gong, Yong-bo Wang, Zhao-bo Chen, Bin-shuang Pang, Xian-chao Chen, Jian-gang Gao, Wei-bing Yang, Feng-ting Zhang, Yi-miao Tang, Chang-ping Zhao and Shi-qing Gao

    Citation: BMC Genomics 2021 22:911

    Content type: Research

    Published on:

  17. Identification of epistatic interactions provides a systematic way for exploring associations among different single nucleotide polymorphism (SNP) and complex diseases. Although considerable progress has been ...

    Authors: Yu Zhong Peng, Yanmei Lin, Yiran Huang, Ying Li, Guangsheng Luo and Jianping Liao

    Citation: BMC Genomics 2021 22(Suppl 1):910

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 22 Supplement 1

  18. Intellectual disability (ID) can be caused by non-genetic and genetic factors, the latter being responsible for more than 1700 ID-related disorders. The broad ID phenotypic and genetic heterogeneity, as well a...

    Authors: Nuno Maia, Maria João Nabais Sá, Manuel Melo-Pires, Arjan P. M. de Brouwer and Paula Jorge

    Citation: BMC Genomics 2021 22:909

    Content type: Review

    Published on:

  19. Biological mutagens (such as transposon) with sequences inserted, play a crucial role to link observed phenotype and genotype in reverse genetic studies. For this reason, accurate and efficient software tools ...

    Authors: Rui Song, Ziyao Wang, Hui Wang, Han Zhang, Xuemeng Wang, Hanh Nguyen, David Holding, Bin Yu, Tom Clemente, Shangang Jia and Chi Zhang

    Citation: BMC Genomics 2021 22:908

    Content type: Software

    Published on:

  20. Cystic and alveolar echinococcosis caused by the tapeworms Echinococcus granulosus sensu stricto (s.s.) and E. multilocularis, respectively, are important zoonotic diseases. Protease inhibitors are crucial for...

    Authors: Hui Zhang, Mengxiao Tian, Wenjing Qi, Juan Wu, Huajun Zheng, Gang Guo, Liang Zhang, Shiwanthi L. Ranasinghe, Donald P. McManus, Jun Li and Wenbao Zhang

    Citation: BMC Genomics 2021 22:907

    Content type: Research

    Published on:

  21. Disruption of alveolar epithelial cell (AEC) differentiation is implicated in distal lung diseases such as chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, and lung adenocarcinoma that imp...

    Authors: B. Zhou, T. R. Stueve, E. A. Mihalakakos, L. Miao, D. Mullen, Y. Wang, Y. Liu, J. Luo, E. Tran, K. D. Siegmund, S. K. Lynch, A. L. Ryan, I. A. Offringa, Z. Borok and C. N. Marconett

    Citation: BMC Genomics 2021 22:906

    Content type: Research article

    Published on:

  22. German Black Pied cattle (DSN) are an endangered dual-purpose breed which was largely replaced by Holstein cattle due to their lower milk yield. DSN cattle are kept as a genetic reserve with a current herd siz...

    Authors: Guilherme B. Neumann, Paula Korkuć, Danny Arends, Manuel J. Wolf, Katharina May, Monika Reißmann, Salma Elzaki, Sven König and Gudrun A. Brockmann

    Citation: BMC Genomics 2021 22:905

    Content type: Research

    Published on:

  23. Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in the liver parenchyma and tissue remodelling. Different cell types...

    Authors: Maciej Migdał, Eugeniusz Tralle, Karim Abu Nahia, Łukasz Bugajski, Katarzyna Zofia Kędzierska, Filip Garbicz, Katarzyna Piwocka, Cecilia Lanny Winata and Michał Pawlak

    Citation: BMC Genomics 2021 22:904

    Content type: Research

    Published on:

  24. Myelodysplastic syndromes (MDS) are clonal disorders of hematopoietic stem cells exhibiting ineffective hematopoiesis and tendency for transformation into acute myeloid leukemia (AML). The available karyotypin...

    Authors: Nida Anwar, Faheem Ahmed Memon, Saba Shahid, Muhammad Shakeel, Muhammad Irfan, Aisha Arshad, Arshi Naz, Ikram Din Ujjan and Tahir Shamsi

    Citation: BMC Genomics 2021 22:903

    Content type: Research

    Published on:

  25. Sickle cell disease (SCD) is an important cause of under-five mortality. Tanzania is the 5th country in the world with the highest births prevalence of SCD individuals. Significant advances in the neonatal dia...

    Authors: Heavenlight Christopher, Adam Burns, Emmanuel Josephat, Julie Makani, Anna Schuh and Siana Nkya

    Citation: BMC Genomics 2021 22:902

    Content type: Research

    Published on:

  26. Satellite cells are the myogenic precursor cells in adult skeletal muscle. The objective of this study was to identify enhancers and transcription factors that regulate gene expression during the differentiati...

    Authors: Pengcheng Lyu, Robert E. Settlage and Honglin Jiang

    Citation: BMC Genomics 2021 22:901

    Content type: Research

    Published on:

  27. Pre-harvest sprouting (PHS) is a major problem for wheat production due to its direct detrimental effects on wheat yield, end-use quality and seed viability. Annually, PHS is estimated to cause > 1.0 billion U...

    Authors: Raman Dhariwal, Colin W. Hiebert, Mark E. Sorrells, Dean Spaner, Robert J. Graf, Jaswinder Singh and Harpinder S. Randhawa

    Citation: BMC Genomics 2021 22:900

    Content type: Research

    Published on:

  28. Ovarian follicle development plays an important role in determination of poultry egg production. The follicles at the various developmental stages possess their own distinct molecular genetic characteristics a...

    Authors: Xue Sun, Xiaoxia Chen, Jinghua Zhao, Chang Ma, Chunchi Yan, Simushi Liswaniso, Rifu Xu and Ning Qin

    Citation: BMC Genomics 2021 22:899

    Content type: Research

    Published on:

  29. Genetic and functional genomics studies require a high-quality genome assembly. Tomato (Solanum lycopersicum), an important horticultural crop, is an ideal model species for the study of fruit development.

    Authors: Xiao Su, Baoan Wang, Xiaolin Geng, Yuefan Du, Qinqin Yang, Bin Liang, Ge Meng, Qiang Gao, Wencai Yang, Yingfang Zhu and Tao Lin

    Citation: BMC Genomics 2021 22:898

    Content type: Research

    Published on:

  30. The general picture of human genetic variation has been vastly depicted in the last years, yet many populations remain broadly understudied. In this work, we analyze for the first time the Merchero population,...

    Authors: André Flores-Bello, Neus Font-Porterias, Julen Aizpurua-Iraola, Sara Duarri-Redondo and David Comas

    Citation: BMC Genomics 2021 22:897

    Content type: Research

    Published on:

  31. Mating induces behavioral and physiological changes in the arbovirus vector Aedes aegypti, including stimulation of egg development and oviposition, increased survival, and reluctance to re-mate with subsequent m...

    Authors: I. Alexandra Amaro, Yasir H. Ahmed-Braimah, Garrett P. League, Sylvie A. Pitcher, Frank W. Avila, Priscilla C. Cruz, Laura C. Harrington and Mariana F. Wolfner

    Citation: BMC Genomics 2021 22:896

    Content type: Research

    Published on:

  32. Authors: Kerstin Neubert, Eric Zuchantke, Robert Maximilian Leidenfrost, Röbbe Wünschiers, Josephine Grützke, Burkhard Malorny, Holger Brendebach, Sascha Al Dahouk, Timo Homeier, Helmut Hotzel, Knut Reinert, Herbert Tomaso and Anne Busch

    Citation: BMC Genomics 2021 22:895

    Content type: Correction

    Published on:

    The original article was published in BMC Genomics 2021 22:822

  33. Wolbachia wMel is the most commonly used strain in rear and release strategies for Aedes aegypti mosquitoes that aim to inhibit the transmission of arboviruses such as dengue, Zika, Chikungunya and yellow fever....

    Authors: Meng-Jia Lau, Thomas L. Schmidt, Qiong Yang, Jessica Chung, Lucien Sankey, Perran A. Ross and Ary A. Hoffmann

    Citation: BMC Genomics 2021 22:894

    Content type: Research

    Published on:

  34. Leaf senescence delay impacts positively in grain yield by maintaining the photosynthetic area during the reproductive stage and during grain filling. Therefore a comprehensive understanding of the gene famili...

    Authors: Sofia A. Bengoa Luoni, Alberto Cenci, Sebastian Moschen, Salvador Nicosia, Laura M. Radonic, Julia V. Sabio y García, Nicolas B. Langlade, Denis Vile, Cecilia Vazquez Rovere and Paula Fernandez

    Citation: BMC Genomics 2021 22:893

    Content type: Research

    Published on:

    The Correction to this article has been published in BMC Genomics 2022 23:24

  35. Insecticide-treated bed nets and indoor residual spraying comprise the major control measures against Anopheles gambiae sl, the dominant vector in sub-Saharan Africa. The primary site of contact with insecticide ...

    Authors: M. Kefi, J. Charamis, V. Balabanidou, P. Ioannidis, H. Ranson, V. A. Ingham and J. Vontas

    Citation: BMC Genomics 2021 22:891

    Content type: Research

    Published on:

  36. Avian necrotic enteritis (NE) caused by Clostridium perfringens is a disease with a major economic impact, generating losses estimated to 6 billion of dollars annually for the poultry industry worldwide. The inci...

    Authors: Ilhem Meniaï, Alexandre Thibodeau, Sylvain Quessy, Valeria R. Parreira, Philippe Fravalo, Guy Beauchamp and Marie-Lou Gaucher

    Citation: BMC Genomics 2021 22:890

    Content type: Research

    Published on:

  37. Pyramiding different resistance genes into one plant genotype confers enhanced resistance at the phenotypic level, but the molecular mechanisms underlying this effect are not well-understood. In soybean, aphid...

    Authors: Martha I. Natukunda, Jessica D. Hohenstein, Chantal E. McCabe, Michelle A. Graham, Yunhui Qi, Asheesh K. Singh and Gustavo C. MacIntosh

    Citation: BMC Genomics 2021 22:887

    Content type: Research article

    Published on:

  38. Recently, ProFAT and BATLAS studies identified brown and white adipocytes marker genes based on analysis of large databases. They offered scores to determine the thermogenic status of adipocytes using the gene...

    Authors: Beáta B. Tóth, Zoltán Barta, Ákos Barnabás Barta and László Fésüs

    Citation: BMC Genomics 2021 22:886

    Content type: Database

    Published on:

  39. Rose is one of the most popular flowers in the wold. Its field growth and quality are negatively affected by aphids. However, the defence mechanisms used by rose plants against aphids are unclear. Therefore, t...

    Authors: Penghua Gao, Hao Zhang, Huijun Yan, Ningning Zhou, Bo Yan, Yuanlan Fan, Kaixue Tang and Xianqin Qiu

    Citation: BMC Genomics 2021 22:885

    Content type: Research

    Published on:

  40. Bovine viral diarrhea virus (BVDV) is a major pathogen that causes bovine viral diarrhea/mucosal disease (BVD-MD), which has become a global infectious disease due to its wide spread and the lack of effective ...

    Authors: Yanping Li, Tingli Liu, Guoliang Chen, Liqun Wang, Aimin Guo, Zhi Li, Li Pan, Li Mao and Xuenong Luo

    Citation: BMC Genomics 2021 22:884

    Content type: Research

    Published on:

  41. The node of the first fruiting branch (NFFB) is an important precocious trait in cotton. Many studies have been conducted on the localization of quantitative trait loci (QTLs) and genes related to fiber qualit...

    Authors: Jingjing Zhang, Xiaoyun Jia, Xiaohao Guo, Hengling Wei, Meng Zhang, Aimin Wu, Shuaishuai Cheng, Xiaoqian Cheng, Shuxun Yu and Hantao Wang

    Citation: BMC Genomics 2021 22:882

    Content type: Research

    Published on:

  42. The Stephania tetrandra S. Moore (S. tetrandra) is a medicinal plant belonging to the family Menispermaceae that has high medicinal value and is well worth doing further exploration. The wild resources of S. tetr...

    Authors: Shujie Dong, Zhiqi Ying, Shuisheng Yu, Qirui Wang, Guanghui Liao, Yuqing Ge and Rubin Cheng

    Citation: BMC Genomics 2021 22:880

    Content type: Research

    Published on:

  43. Coilia nasus is an important anadromous fish, widely distributed in China, Japan, and Korea. Based on morphological and ecological researches of C. nasus, two ecotypes were identified. One is the anadromous popul...

    Authors: Jun Gao, Gangchun Xu and Pao Xu

    Citation: BMC Genomics 2021 22:878

    Content type: Research

    Published on:

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