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  1. Gene targeting by homology-directed repair (HDR) can precisely edit the genome and is a versatile tool for biomedical research. However, the efficiency of HDR-based modification is still low in many model orga...

    Authors: Haipeng Bai, Lijun Liu, Ke An, Xiaochan Lu, Michael Harrison, Yanqiu Zhao, Ruibin Yan, Zhijie Lu, Song Li, Shuo Lin, Fang Liang and Wei Qin

    Citation: BMC Genomics 2020 21:67

    Content type: Methodology article

    Published on:

  2. Houseflies (Musca domestica L.) live in intimate association with numerous microorganisms and is a vector of human pathogens. In temperate areas, houseflies will overwinter in environments constructed by humans a...

    Authors: Simon Bahrndorff, Aritz Ruiz-González, Nadieh de Jonge, Jeppe Lund Nielsen, Henrik Skovgård and Cino Pertoldi

    Citation: BMC Genomics 2020 21:66

    Content type: Research article

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  3. Alternative splicing (AS) may generate multiple mRNA splicing isoforms from a single mRNA precursor using different splicing sites, leading to enhanced diversity of transcripts and proteins. AS has been implic...

    Authors: Yeyun Li, Xiaozeng Mi, Shiqi Zhao, Junyan Zhu, Rui Guo, Xiaobo Xia, Lu Liu, Shengrui Liu and Chaoling Wei

    Citation: BMC Genomics 2020 21:65

    Content type: Research article

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  4. The advent of Next Generation Sequencing has allowed transcriptomes to be profiled with unprecedented accuracy, but the high costs of full-length mRNA sequencing have posed a limit on the accessibility and sca...

    Authors: Gabriel Sholder, Thomas A. Lanz, Robert Moccia, Jie Quan, Estel Aparicio-Prat, Robert Stanton and Hualin S. Xi

    Citation: BMC Genomics 2020 21:64

    Content type: Methodology article

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  5. As a major threat to the oyster industry, Pacific Oyster Mortality Syndrome (POMS) is a polymicrobial disease affecting the main oyster species farmed across the world. POMS affects oyster juveniles and became...

    Authors: Julien de Lorgeril, Bruno Petton, Aude Lucasson, Valérie Perez, Pierre-Louis Stenger, Lionel Dégremont, Caroline Montagnani, Jean-Michel Escoubas, Philippe Haffner, Jean-François Allienne, Marc Leroy, Franck Lagarde, Jérémie Vidal-Dupiol, Yannick Gueguen and Guillaume Mitta

    Citation: BMC Genomics 2020 21:63

    Content type: Research article

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  6. The APETALA2/ethylene responsive factor (AP2/ERF) superfamily members are transcription factors that regulate diverse developmental processes and stress responses in plants. They have been identified in many p...

    Authors: Shuting Zhang, Chen Zhu, Yumeng Lyu, Yan Chen, Zihao Zhang, Zhongxiong Lai and Yuling Lin

    Citation: BMC Genomics 2020 21:62

    Content type: Research article

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  7. Structural variations (SVs) have been reported to play an important role in genetic diversity and trait regulation. Many computer algorithms detecting SVs have recently been developed, but the use of multiple ...

    Authors: Yueyuan Liu, Mingyue Zhang, Jieying Sun, Wenjing Chang, Manyi Sun, Shaoling Zhang and Jun Wu

    Citation: BMC Genomics 2020 21:61

    Content type: Research article

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  8. Lactoferrampin (LFampin), Lactoferricin (LFcin), and LFchimera are three well-known antimicrobial peptides derived from Lactoferrin and proposed as alternatives for antibiotics. Although the intracellular acti...

    Authors: Zana Pirkhezranian, Mojtaba Tahmoorespur, Xavier Daura, Hassan Monhemi and Mohammad Hadi Sekhavati

    Citation: BMC Genomics 2020 21:60

    Content type: Research article

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  9. Reproductive capacity can be altered by challenges experienced during critical periods of development, including fetal development and early neonatal life. Gossypol is a polyphenolic compound, commonly found i...

    Authors: Helder Louvandini, Patricia S. Corrêa, Rocío Amorín, Lihe Liu, Egon H. Ieda, Carolina R. Jimenez, Siu M. Tsai, Concepta M. McManus and Francisco Peñagaricano

    Citation: BMC Genomics 2020 21:59

    Content type: Research article

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  10. Fatty acid composition contributes greatly to the quality and nutritional value of meat. However, the molecular regulatory mechanisms underlying fatty acid accumulation in poultry have not yet been cleared. Th...

    Authors: Wenlei Fan, Wenjing Liu, Hehe Liu, Qingshi Meng, Yaxi Xu, Yuming Guo, Baowei Wang, Zhengkui Zhou and Shuisheng Hou

    Citation: BMC Genomics 2020 21:58

    Content type: Research article

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  11. Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study, we aim to explore the phenotyp...

    Authors: Jiaping Wang, Yu Liu, Guangxian Zhao, Jianyi Gao, Junlian Liu, Xiaorui Wu, Chong Xu and Yongzhi Li

    Citation: BMC Genomics 2020 21:57

    Content type: Research article

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  12. Shotgun metagenomic sequencing reveals the potential in microbial communities. However, lower-cost 16S ribosomal RNA (rRNA) gene sequencing provides taxonomic, not functional, observations. To remedy this, we ...

    Authors: Nicole R. Narayan, Thomas Weinmaier, Emilio J. Laserna-Mendieta, Marcus J. Claesson, Fergus Shanahan, Karim Dabbagh, Shoko Iwai and Todd Z. DeSantis

    Citation: BMC Genomics 2020 21:56

    Content type: Research article

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    The Correction to this article has been published in BMC Genomics 2020 21:105

  13. Following the publication of this article [1], the authors reported that the captions of Figs. 3 and 4 were published in the incorrect order, whereby they mismatch with their corresponding images.

    Authors: Robert Bücking, Murray P. Cox, Georgi Hudjashov, Lauri Saag, Herawati Sudoyo and Mark Stoneking

    Citation: BMC Genomics 2020 21:55

    Content type: Correction

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    The original article was published in BMC Genomics 2019 20:1017

  14. Carotenoids contribute significantly to animal body coloration, including the spectacular color pattern diversity among fishes. Fish, as other animals, derive carotenoids from their diet. Following uptake, tra...

    Authors: Ehsan Pashay Ahi, Laurène A. Lecaudey, Angelika Ziegelbecker, Oliver Steiner, Ronald Glabonjat, Walter Goessler, Victoria Hois, Carina Wagner, Achim Lass and Kristina M. Sefc

    Citation: BMC Genomics 2020 21:54

    Content type: Research article

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  15. Ca2+ played as a ubiquitous secondary messenger involved in plant growth, development, and responses to various environmental stimuli. Calcium-dependent protein kinases (CDPK) were important Ca2+ sensors, which c...

    Authors: Feng Wen, Feng Ye, Zhulong Xiao, Liang Liao, Tongjian Li, Mingliang Jia, Xinsheng Liu and Xiaozhu Wu

    Citation: BMC Genomics 2020 21:53

    Content type: Research article

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  16. Pennisetum giganteum, an abundant, fast-growing perennial C4 grass that belongs to the genus Pennisetum, family Poaceae, has been developed as a source of biomass for mushroom cultivation and production, as a sou...

    Authors: Qingyuan Li, Conglin Xiang, Lin Xu, Jinghua Cui, Shao Fu, Baolin Chen, Shoukun Yang, Pan Wang, Yanfeng Xie, Ming Wei and Zhanchang Wang

    Citation: BMC Genomics 2020 21:52

    Content type: Research article

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  17. Following the publication of the original article [1], it was reported that the accession number given in the ‘Data accessibility’ declaration, GSE65696, is incorrect.

    Authors: Zhaowei Cai, Xiaoling Jiang, Yongming Pan, Liang Chen, Lifan Zhang, Keyan Zhu, Yueqin Cai, Yun Ling, Fangming Chen, Xiaoping Xu and Minli Chen

    Citation: BMC Genomics 2020 21:51

    Content type: Correction

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    The original article was published in BMC Genomics 2015 16:59

  18. The Tibial dyschondroplasia (TD) in fast-growing chickens is mainly caused by improper blood circulation. The exact mechanism underlying angiogenesis and vascularization in tibial growth plate of broiler chick...

    Authors: Ali Raza Jahejo, Ding Zhang, Sheng Niu, Raza Ali Mangi, Afrasyab Khan, Muhammad Farhan Qadir, Ajab Khan, Huan-chun Chen and Wen-xia Tian

    Citation: BMC Genomics 2020 21:50

    Content type: Research article

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  19. Clinopodium gracile (Benth.) Matsum (C. gracile) is an annual herb with pharmacological properties effective in the treatment of various diseases, including hepatic carcinoma. Triterpenoid saponins are crucial bi...

    Authors: Chunmiao Shan, Chenkai Wang, Shengxiang Zhang, Yuanyuan Shi, Kelong Ma, Qingshan Yang and Jiawen Wu

    Citation: BMC Genomics 2020 21:49

    Content type: Research article

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  20. Crop wild relatives (CWRs) contain genetic diversity, representing an invaluable resource for crop improvement. Many of their traits have the potential to help crops to adapt to changing conditions that they e...

    Authors: Antonios Kioukis, Vassiliki A. Michalopoulou, Laura Briers, Stergios Pirintsos, David J. Studholme, Pavlos Pavlidis and Panagiotis F. Sarris

    Citation: BMC Genomics 2020 21:48

    Content type: Research article

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  21. The red flour beetle Tribolium castaneum has emerged as an important model organism for the study of gene function in development and physiology, for ecological and evolutionary genomics, for pest control and a p...

    Authors: Nicolae Herndon, Jennifer Shelton, Lizzy Gerischer, Panos Ioannidis, Maria Ninova, Jürgen Dönitz, Robert M. Waterhouse, Chun Liang, Carsten Damm, Janna Siemanowski, Peter Kitzmann, Julia Ulrich, Stefan Dippel, Georg Oberhofer, Yonggang Hu, Jonas Schwirz…

    Citation: BMC Genomics 2020 21:47

    Content type: Research article

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  22. Increasing evidence has shown that circular RNAs (circRNAs) are involved in neurodegenerative disorders, but their roles in neurological toxoplasmosis are yet to know. This study examined miRNA and circRNA exp...

    Authors: Chun-Xue Zhou, Kang Ai, Cui-Qin Huang, Jing-Jing Guo, Hua Cong, Shen-Yi He and Xing-Quan Zhu

    Citation: BMC Genomics 2020 21:46

    Content type: Research article

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  23. Clostridium perfringens is a Gram-positive anaerobic pathogen that causes multiple diseases in humans and animals. C. perfringens lack flagella but have type IV pili (TFP) and can glide on agar surfaces. When C. ...

    Authors: Samantha R. Soncini, Andrea H. Hartman, Tara M. Gallagher, Gary J. Camper, Roderick V. Jensen and Stephen B. Melville

    Citation: BMC Genomics 2020 21:45

    Content type: Research article

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  24. Ladybird beetles (Coleoptera, Coccinellidae) are highly diverse in their feeding habits. Most of them are specialist feeders, while some can have a broad spectrum of prey. As a representative group of generali...

    Authors: Mei-Lan Chen, Yu-Hao Huang, Bo-Yuan Qiu, Pei-Tao Chen, Xue-Yong Du, Hao-Sen Li and Hong Pang

    Citation: BMC Genomics 2020 21:44

    Content type: Research article

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  25. Genomic prediction (GP) is used in animal and plant breeding to help identify the best genotypes for selection. One of the most important measures of the effectiveness and reliability of GP in plant breeding i...

    Authors: Vanda Milheiro Lourenço, Joseph Ochieng Ogutu and Hans-Peter Piepho

    Citation: BMC Genomics 2020 21:43

    Content type: Methodology Article

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  27. Health traits are of significant economic importance to the dairy industry due to their effects on milk production and associated treatment costs. Genome-wide association studies (GWAS) provide a means to iden...

    Authors: Ellen Freebern, Daniel J. A. Santos, Lingzhao Fang, Jicai Jiang, Kristen L. Parker Gaddis, George E. Liu, Paul M. VanRaden, Christian Maltecca, John B. Cole and Li Ma

    Citation: BMC Genomics 2020 21:41

    Content type: Research article

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  28. Boehmeria nivea L. Gaud (Ramie) produces one of the longest natural fibers in nature. The bark of ramie mainly comprises of the phloem tissue of stem and is the raw material for fiber. Therefore, identifying the ...

    Authors: Jiyong Xie, Jiaqi Li, Yucheng Jie, Deyu Xie, Di Yang, Huazhong Shi and Yingli Zhong

    Citation: BMC Genomics 2020 21:40

    Content type: Research article

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  29. Hypoxia mediated pulmonary hypertension (HPH) is a lethal disease and lacks effective therapy. CircRNAs play significant roles in physiological process. Recently, circRNAs are found to be m6A-modified. The abunda...

    Authors: Hua Su, Guowen Wang, Lingfang Wu, Xiuqing Ma, Kejing Ying and Ruifeng Zhang

    Citation: BMC Genomics 2020 21:39

    Content type: Research article

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  30. Genome wide association studies (GWAS) were conducted on 7,853,211 imputed whole genome sequence variants in a population of 3354 to 3984 animals from multiple beef cattle breeds for five carcass merit traits ...

    Authors: Yining Wang, Feng Zhang, Robert Mukiibi, Liuhong Chen, Michael Vinsky, Graham Plastow, John Basarab, Paul Stothard and Changxi Li

    Citation: BMC Genomics 2020 21:38

    Content type: Research article

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  31. Light is the main source of energy and, as such, is one of the most important environmental factors for plant growth, morphogenesis, and other physiological responses. MicroRNAs (miRNAs) are endogenous non-cod...

    Authors: Fei Dong, Chuanzeng Wang, Yuhui Dong, Shuqin Hao, Lixia Wang, Xiudong Sun and Shiqi Liu

    Citation: BMC Genomics 2020 21:37

    Content type: Research article

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  32. Genome wide association studies (GWAS) on residual feed intake (RFI) and its component traits including daily dry matter intake (DMI), average daily gain (ADG), and metabolic body weight (MWT) were conducted i...

    Authors: Feng Zhang, Yining Wang, Robert Mukiibi, Liuhong Chen, Michael Vinsky, Graham Plastow, John Basarab, Paul Stothard and Changxi Li

    Citation: BMC Genomics 2020 21:36

    Content type: Research article

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  33. RNA sequencing allows the measuring of gene expression at a resolution unmet by expression arrays or RT-qPCR. It is however necessary to normalize sequencing data by library size, transcript size and compositi...

    Authors: Karen Cristine Gonçalves dos Santos, Isabel Desgagné-Penix and Hugo Germain

    Citation: BMC Genomics 2020 21:35

    Content type: Methodology article

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  34. Venom is one of the most important sources of regulation factors used by parasitic Hymenoptera to redirect host physiology in favour of the developing offspring. This has stimulated a number of studies, both a...

    Authors: Andrea Becchimanzi, Maddalena Avolio, Hamed Bostan, Chiara Colantuono, Flora Cozzolino, Donato Mancini, Maria Luisa Chiusano, Pietro Pucci, Silvia Caccia and Francesco Pennacchio

    Citation: BMC Genomics 2020 21:34

    Content type: Research article

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  35. Spirochetal organisms of the Treponema genus are responsible for causing Treponematoses. Pathogenic treponemes is a Gram-negative, motile, spirochete pathogen that causes syphilis in human. Treponema pallidum sub...

    Authors: Arun Kumar Jaiswal, Sandeep Tiwari, Syed Babar Jamal, Letícia de Castro Oliveira, Leandro Gomes Alves, Vasco Azevedo, Preetam Ghosh, Carlo Jose Freira Oliveira and Siomar C. Soares

    Citation: BMC Genomics 2020 21:33

    Content type: Research article

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  36. Decapods are an order of crustaceans which includes shrimps, crabs, lobsters and crayfish. They occur worldwide and are of great scientific interest as well as being of ecological and economic importance in fi...

    Authors: Wenyan Nong, Zacary Y. H. Chai, Xiaosen Jiang, Jing Qin, Ka Yan Ma, King Ming Chan, Ting Fung Chan, Billy K. C. Chow, Hoi Shan Kwan, Chris K. C. Wong, Jian-Wen Qiu, Jerome H. L. Hui and Ka Hou Chu

    Citation: BMC Genomics 2020 21:32

    Content type: Database

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  37. The general combining ability (GCA) of parents in hybrid rice affects not only heterotic level of grain yield and other important agronomic traits, but also performance of grain quality traits of F2 bulk populati...

    Authors: Moaz S. Eltahawy, Nour Ali, Imdad U. Zaid, Dalu Li, Dina Abdulmajid, Lal Bux, Hui Wang and Delin Hong

    Citation: BMC Genomics 2020 21:31

    Content type: Research article

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  38. Following the publication of this article [1], the authors noted an error in Figure 11.

    Authors: Sapinder Bali, Kelly Vining, Cynthia Gleason, Hassan Majtahedi, Charles R. Brown and Vidyasagar Sathuvalli

    Citation: BMC Genomics 2020 21:30

    Content type: Correction

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    The original article was published in BMC Genomics 2019 20:907

  39. Anthocyanins are common substances with many agro-food industrial applications. However, anthocyanins are generally considered to be found only in natural plants. Our previous study isolated and purified the f...

    Authors: Congfan Bu, Qian Zhang, Jie Zeng, Xiyue Cao, Zhaonan Hao, Dairong Qiao, Yi Cao and Hui Xu

    Citation: BMC Genomics 2020 21:29

    Content type: Research article

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  40. Fusarium circinatum, the causal agent of pitch canker disease, poses a serious threat to several Pinus species affecting plantations and nurseries. Although Pinus pinaster has shown moderate resistance to F. circ...

    Authors: Laura Hernandez-Escribano, Erik A. Visser, Eugenia Iturritxa, Rosa Raposo and Sanushka Naidoo

    Citation: BMC Genomics 2020 21:28

    Content type: Research article

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  41. Autochthonous cattle breeds are an important source of genetic variation because they might carry alleles that enable them to adapt to local environment and food conditions. Original Braunvieh (OB) is a local ...

    Authors: Meenu Bhati, Naveen Kumar Kadri, Danang Crysnanto and Hubert Pausch

    Citation: BMC Genomics 2020 21:27

    Content type: Research article

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  43. DNA double-stranded breaks (DSBs) are potentially deleterious events in a cell. The end structures (blunt, 3′- and 5′-overhangs) at DSB sites contribute to the fate of their repair and provide critical informa...

    Authors: Karol Szlachta, Heather M. Raimer, Laurey D. Comeau and Yuh-Hwa Wang

    Citation: BMC Genomics 2020 21:25

    Content type: Methodology article

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  44. The genus Trichococcus currently contains nine species: T. flocculiformis, T. pasteurii, T. palustris, T. collinsii, T. patagoniensis, T. ilyis, T. paludicola, T. alkaliphilus, and T. shcherbakoviae. In general,

    Authors: Nikolaos Strepis, Henry D. Naranjo, Jan Meier-Kolthoff, Markus Göker, Nicole Shapiro, Nikos Kyrpides, Hans-Peter Klenk, Peter J. Schaap, Alfons J. M. Stams and Diana Z. Sousa

    Citation: BMC Genomics 2020 21:24

    Content type: Research article

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  46. Early sex differentiation genes of zebrafish remain an unsolved mystery due to the difficulty to distinguish the sex of juvenile zebrafish. However, aromatase inhibitors (AIs) could direct juvenile zebrafish s...

    Authors: Lu Chen, Li Wang, Qiwei Cheng, Yi-Xuan Tu, Zhuang Yang, Run-Ze Li, Zhi-Hui Luo and Zhen-Xia Chen

    Citation: BMC Genomics 2020 21:22

    Content type: Research article

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  47. Growth hormone inducible transmembrane protein (GHITM) is a highly conserved transmembrane protein. This study was conducted to investigate the role of GHITM gene in the apoptosis and growth of the golden appl...

    Authors: Wenchao Yu, Baolu Zhang, Hongce Song, Rui Zhan, Lingling Li, Cheng He, Qiuyun Jiang, Xiaona Wang, Lei Wei, Nannan Zhao, Wen Guo and Xiaotong Wang

    Citation: BMC Genomics 2020 21:19

    Content type: Research article

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  48. Potato virus Y (PVY) is a major pathogen of potatoes with major impact on global agricultural production. Resistance to PVY can be achieved by engineering potatoes to express a recessive, resistant allele of e...

    Authors: Pablo A. Gutierrez Sanchez, Lavanya Babujee, Helena Jaramillo Mesa, Erica Arcibal, Megan Gannon, Dennis Halterman, Molly Jahn, Jiming Jiang and Aurélie M. Rakotondrafara

    Citation: BMC Genomics 2020 21:18

    Content type: Research article

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  49. Cotton grows in altering environments that are often unfavorable or stressful for its growth and development. Consequently, the plant must cope with abiotic stresses such as soil salinity, drought, and excessi...

    Authors: Yanchao Xu, Richard Odongo Magwanga, Xiu Yang, Dingsha Jin, Xiaoyan Cai, Yuqing Hou, Yangyang Wei, Zhongli Zhou, Kunbo Wang and Fang Liu

    Citation: BMC Genomics 2020 21:15

    Content type: Research article

    Published on:

  50. Myopia is one of the most common vision defects worldwide. microRNAs can regulate the target gene expression, influencing the development of diseases.

    Authors: Dadong Guo, Meihua Ding, Xiaoli Song, Yuanyuan Sun, Guoping Li, Zonghong Li, Huixia Wei, Jianfeng Wu, Wenjun Jiang and Hongsheng Bi

    Citation: BMC Genomics 2020 21:13

    Content type: Research article

    Published on:

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