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  1. The Collaborative Cross (CC) mouse population is a valuable resource to study the genetic basis of complex traits, such as obesity. Although the development of obesity is influenced by environmental factors, u...

    Authors: Ilona Binenbaum, Hanifa Abu-Toamih Atamni, Georgios Fotakis, Georgia Kontogianni, Theodoros Koutsandreas, Eleftherios Pilalis, Richard Mott, Heinz Himmelbauer, Fuad A. Iraqi and Aristotelis A. Chatziioannou
    Citation: BMC Genomics 2020 21:761
  2. Abiotic stress, including heat, is one of the major factors that affect alfalfa growth and forage yield. The small RNA, microRNA156 (miR156), regulates multiple traits in alfalfa during abiotic stress. The aim...

    Authors: Muhammad Arshad, Alpa Puri, Aaron J. Simkovich, Justin Renaud, Margaret Y. Gruber, Frédéric Marsolais and Abdelali Hannoufa
    Citation: BMC Genomics 2020 21:758
  3. Unveiling fungal genome structure and function reveals the potential biotechnological use of fungi. Trichoderma harzianum is a powerful CAZyme-producing fungus. We studied the genomic regions in T. harzianum IOC3...

    Authors: Jaire A. Ferreira Filho, Maria Augusta C. Horta, Clelton A. dos Santos, Deborah A. Almeida, Natália F. Murad, Juliano S. Mendes, Danilo A. Sforça, Claudio Benício C. Silva, Aline Crucello and Anete P. de Souza
    Citation: BMC Genomics 2020 21:757
  4. Recent advances in single-cell RNA sequencing have allowed researchers to explore transcriptional function at a cellular level. In particular, single-cell RNA sequencing reveals that there exist clusters of ce...

    Authors: Florian Klimm, Enrique M. Toledo, Thomas Monfeuga, Fang Zhang, Charlotte M. Deane and Gesine Reinert
    Citation: BMC Genomics 2020 21:756
  5. With 9730 protein-coding genes and a nearly complete gene knockout strain collection, Neurospora crassa is a major model organism for filamentous fungi. Despite this abundance of information, the phenotypes of th...

    Authors: Alexander J. Carrillo, Ilva E. Cabrera, Marko J. Spasojevic, Patrick Schacht, Jason E. Stajich and Katherine A. Borkovich
    Citation: BMC Genomics 2020 21:755
  6. Efforts to elucidate the function of enhancers in vivo are underway but their vast numbers alongside differing enhancer architectures make it difficult to determine their impact on gene activity. By systematic...

    Authors: Siddharth Sethi, Ilya E. Vorontsov, Ivan V. Kulakovskiy, Simon Greenaway, John Williams, Vsevolod J. Makeev, Steve D. M. Brown, Michelle M. Simon and Ann-Marie Mallon
    Citation: BMC Genomics 2020 21:754
  7. The development of skeletal muscle is closely related to the efficiency of meat production and meat quality. Chicken skeletal muscle development depends on myogenesis and adipogenesis and occurs in two phases—...

    Authors: Jinghui Li, Siyuan Xing, Guiping Zhao, Maiqing Zheng, Xinting Yang, Jiahong Sun, Jie Wen and Ranran Liu
    Citation: BMC Genomics 2020 21:752
  8. The human transcriptome annotation is regarded as one of the most complete of any eukaryotic species. However, limitations in sequencing technologies have biased the annotation toward multi-exonic protein codi...

    Authors: Richard I. Kuo, Yuanyuan Cheng, Runxuan Zhang, John W. S. Brown, Jacqueline Smith, Alan L. Archibald and David W. Burt
    Citation: BMC Genomics 2020 21:751
  9. Azadirachtin A is a triterpenoid from neem tree exhibiting excellent activities against over 600 insect species in agriculture. The production of azadirachtin A depends on extraction from neem tissues, which i...

    Authors: Huiyan Wang, Ning Wang and Yixin Huo
    Citation: BMC Genomics 2020 21:749
  10. Epigenetic clocks have been recognized for their precise prediction of chronological age, age-related diseases, and all-cause mortality. Existing epigenetic clocks are based on CpGs from the Illumina HumanMeth...

    Authors: Yunsung Lee, Kristine L. Haftorn, William R. P. Denault, Haakon E. Nustad, Christian M. Page, Robert Lyle, Sindre Lee-Ødegård, Gunn-Helen Moen, Rashmi B. Prasad, Leif C. Groop, Line Sletner, Christine Sommer, Maria C. Magnus, Håkon K. Gjessing, Jennifer R. Harris, Per Magnus…
    Citation: BMC Genomics 2020 21:747
  11. In diploid cells, it is important to construct maternal and paternal Hi-C contact maps respectively since the two homologous chromosomes can differ in chromatin three-dimensional (3D) organization. Though prev...

    Authors: Han Luo, Xinxin Li, Haitao Fu and Cheng Peng
    Citation: BMC Genomics 2020 21:746
  12. Temperature is known to affect living organisms and alter the expression of responsive genes, which affects a series of life processes, such as development, reproduction and metabolism. Several genes and gene ...

    Authors: Qian Wang, Xiancai Hao, Kaiqiang Liu, Bo Feng, Shuo Li, Zhihua Zhang, Lili Tang, Shahid Mahboob and Changwei Shao
    Citation: BMC Genomics 2020 21:745
  13. Early diagnosis is crucial for effective medical management of cancer patients. Tissue biopsy has been widely used for cancer diagnosis, but its invasive nature limits its application, especially when repeated...

    Authors: Chitrita Goswami, Smriti Chawla, Deepshi Thakral, Himanshu Pant, Pramod Verma, Prabhat Singh Malik, Jayadeva, Ritu Gupta, Gaurav Ahuja and Debarka Sengupta
    Citation: BMC Genomics 2020 21:744

    The Correction to this article has been published in BMC Genomics 2020 21:877

  14. Scenedesmus obliquus belongs to green microalgae and is widely used in aquaculture as feed, which is also explored for lipid production and bioremediation. However, genomic studies of this microalga have been ver...

    Authors: Bai-Ling Chen, Wuttichai Mhuantong, Shih-Hsin Ho, Jo-Shu Chang, Xin-Qing Zhao and Feng-Wu Bai
    Citation: BMC Genomics 2020 21:743
  15. The production of foie gras involves different metabolic pathways in the liver of overfed ducks such as lipid synthesis and carbohydrates catabolism, but the establishment of these pathways has not yet been de...

    Authors: William Massimino, Stéphane Davail, Aurélie Secula, Charlotte Andrieux, Marie-Dominique Bernadet, Tracy Pioche, Karine Ricaud, Karine Gontier, Mireille Morisson, Anne Collin, Stéphane Panserat and Marianne Houssier
    Citation: BMC Genomics 2020 21:742
  16. Salvia miltiorrhiza is one of the most important traditional Chinese medicinal plants with high medicinal value. Gibberellins are growth-promoting phytohormones that regulate numerous growth and developmental pro...

    Authors: Wenrui Li, Chuangfeng Liu, Jingling Liu, Zhenqing Bai and Zongsuo Liang
    Citation: BMC Genomics 2020 21:727
  17. Finding orthologs remains an important bottleneck in comparative genomics analyses. While the authors of software for the quick comparison of protein sequences evaluate the speed of their software and compare ...

    Authors: Julie E. Hernández-Salmerón and Gabriel Moreno-Hagelsieb
    Citation: BMC Genomics 2020 21:741
  18. Understanding the genetic basis of phenotype variations during domestication and breeding is of great interest. Epigenetics and epigenetic modification enzymes (EMEs) may play a role in phenotypic variations; ...

    Authors: Rui Gao, Chun-Lin Li, Xiao-Ling Tong, Min-Jin Han, Kun-Peng Lu, Shu-Bo Liang, Hai Hu, Yue Luan, Bi-Li Zhang, Yan-Yu Liu and Fang-Yin Dai
    Citation: BMC Genomics 2020 21:740
  19. Different soybean (Glycine max L.) leaf chlorophyll-content traits are considered to be significantly linked to soybean yield. To map the quantitative trait loci (QTLs) of soybean leaf chlorophyll-content traits,...

    Authors: Liang Wang, Brima Conteh, Linzhi Fang, Qiuju Xia and Hai Nian
    Citation: BMC Genomics 2020 21:739
  20. The root lesion nematode Pratylenchus penetrans is a migratory plant-parasitic nematode responsible for economically important losses in a wide number of crops. Despite the importance of P. penetrans, the molecul...

    Authors: Paulo Vieira, Jonathan Shao, Paramasivan Vijayapalani, Thomas R. Maier, Clement Pellegrin, Sebastian Eves-van den Akker, Thomas J. Baum and Lev G. Nemchinov
    Citation: BMC Genomics 2020 21:738
  21. Tropical stenothermal fish exhibit special tolerance and response to cold stress. However current knowledge of the molecular mechanisms response to cold stress in aquatic ectotherms is largely drawn from euryt...

    Authors: Lili Liu, Rong Zhang, Xiaowen Wang, Hua Zhu and Zhaohui Tian
    Citation: BMC Genomics 2020 21:737
  22. TIFY is a plant-specific protein family with a diversity of functions in plant development and responses to stress and hormones, which contains JASMONATE ZIM-domain (JAZ), TIFY, PPD and ZML subfamilies. Despit...

    Authors: Xin He, Yu Kang, Wenqian Li, Wei Liu, Pan Xie, Li Liao, Luyao Huang, Min Yao, Lunwen Qian, Zhongsong Liu, Chunyun Guan, Mei Guan and Wei Hua
    Citation: BMC Genomics 2020 21:736
  23. Transcription factors (TFs) are essential regulators of growth and development in eukaryotes. Basic-helix-loop-helix (bHLHs) is one of the most significant TFs families involved in several critical regulatory ...

    Authors: Mohammad Aslam, Bello Hassan Jakada, Beenish Fakher, Joseph G. Greaves, Xiaoping Niu, Zhenxia Su, Yan Cheng, Shijiang Cao, Xiaomei Wang and Yuan Qin
    Citation: BMC Genomics 2020 21:735
  24. Elucidating the candidate genes and key metabolites responsible for pulp and peel coloration is essential for breeding pitaya fruit with new and improved appeal and high nutritional value. Here, we used transc...

    Authors: Zhaoxi Zhou, Hongmao Gao, Jianhong Ming, Zheli Ding, Xing’e Lin and Rulin Zhan
    Citation: BMC Genomics 2020 21:734

    The Correspondence to this article has been published in BMC Genomics 2022 23:739

    The Correspondence to this article has been published in BMC Genomics 2022 23:740

  25. Microorganisms are not only indispensable to ecosystem functioning, they are also keystones for emerging technologies. In the last 15 years, the number of studies on environmental microbial communities has inc...

    Authors: Lisa Joos, Stien Beirinckx, Annelies Haegeman, Jane Debode, Bart Vandecasteele, Steve Baeyen, Sofie Goormachtig, Lieven Clement and Caroline De Tender
    Citation: BMC Genomics 2020 21:733
  26. Sexual reproduction of scleractinians has captured the attention of researchers and the general public for decades. Although extensive ecological data has been acquired, underlying molecular and cellular mecha...

    Authors: Yi-Ling Chiu, Shinya Shikina, Yuki Yoshioka, Chuya Shinzato and Ching-Fong Chang
    Citation: BMC Genomics 2020 21:732
  27. Domestic yaks play an indispensable role in sustaining the livelihood of Tibetans and other ethnic groups on the Qinghai-Tibetan Plateau (QTP), by providing milk and meat. They have evolved numerous physiologi...

    Authors: Jinwei Xin, Zhixin Chai, Chengfu Zhang, Qiang Zhang, Yong Zhu, Hanwen Cao, Cidan Yangji, Xiaoying Chen, Hui Jiang, Jincheng Zhong and Qiumei Ji
    Citation: BMC Genomics 2020 21:731
  28. Members of the F. oxysporium species complex (FOSC) in the f. sp. apii (Foa) are pathogenic on celery and those in f. sp. coriandrii (Foci) are pathogenic on coriander (=cilantro). Foci was first reported in Cali...

    Authors: Peter Henry, Sukhwinder Kaur, Quyen Anh Tran Pham, Radwan Barakat, Samuel Brinker, Hannah Haensel, Oleg Daugovish and Lynn Epstein
    Citation: BMC Genomics 2020 21:730
  29. The ray floret shapes referred to as petal types on the chrysanthemum (Chrysanthemum × morifolium Ramat.) capitulum is extremely abundant, which is one of the most important ornamental traits of chrysanthemum. Ho...

    Authors: Ya Pu, He Huang, Xiaohui Wen, Chenfei Lu, Bohan Zhang, Xueqi Gu, Shuai Qi, Guangxun Fan, Wenkui Wang and Silan Dai
    Citation: BMC Genomics 2020 21:728
  30. Teleost fish play important roles in aquatic ecosystems and aquaculture. Threadfins (Perciformes: Polynemidae) show a range of interesting biology, and are of considerable importance for both wild fisheries an...

    Authors: Zhe Qu, Wenyan Nong, Yifei Yu, Tobias Baril, Ho Yin Yip, Alexander Hayward and Jerome H. L. Hui
    Citation: BMC Genomics 2020 21:726
  31. Phosphorus (P) is an essential element in maintaining high biomass and yield in crops. Soybean [Glycine max (L.) Merr.] requires a large amount of P during growth and development. Improvement of P efficiency and ...

    Authors: Wenkai Du, Lihua Ning, Yongshun Liu, Shixi Zhang, Yuming Yang, Qing Wang, Shengqian Chao, Hui Yang, Fang Huang, Hao Cheng and Deyue Yu
    Citation: BMC Genomics 2020 21:725
  32. Infectious bursal disease virus (IBDV) causes acute, highly contagious, immunosuppressive, and lethal infectious disease in young chickens and mainly infects the bursa of Fabricius (BF). To investigate interac...

    Authors: Xuewei Huang, Junyan Zhang, Zengsu Liu, Meng Wang, Xiaolong Fan, Li Wang, Han Zhou, Yanping Jiang, Wen Cui, Xinyuan Qiao, Yigang Xu, Yijing Li and Lijie Tang
    Citation: BMC Genomics 2020 21:724
  33. Protein expression patterns underlie physiological processes and phenotypic differences including those occurring during early development. The Pacific oyster (Crassostrea gigas) undergoes a major phenotypic chan...

    Authors: Shelly A. Wanamaker, Kaitlyn R. Mitchell, Rhonda Elliott Thompson, Benoit Eudeline, Brent Vadopalas, Emma B. Timmins-Schiffman and Steven B. Roberts
    Citation: BMC Genomics 2020 21:723

    The Correction to this article has been published in BMC Genomics 2023 24:188

  34. The recent release of the reference genome sequence assembly of flax, a self-pollinated crop with 15 chromosome pairs, into chromosome-scale pseudomolecules enables the characterization of gene families. The A...

    Authors: Nadeem Khan, Frank M. You, Raju Datla, Sridhar Ravichandran, Bosen Jia and Sylvie Cloutier
    Citation: BMC Genomics 2020 21:722
  35. We previously reported on the interplay between miR156/SPL13 and WD40–1/DFR to improve response to drought stress in alfalfa (Medicago sativa L.). Here we aimed to investigate whether the role of miR156/SPL13 mod...

    Authors: Biruk A. Feyissa, Justin Renaud, Vida Nasrollahi, Susanne E. Kohalmi and Abdelali Hannoufa
    Citation: BMC Genomics 2020 21:721
  36. Mutations in the mitochondrial genome have been implicated in mitochondrial disease, often characterized by impaired cellular energy metabolism. Cellular energy metabolism in mitochondria involves mitochondria...

    Authors: Jigme Dorji, Christy J. Vander Jagt, Josie B. Garner, Leah C. Marett, Brett A. Mason, Coralie M. Reich, Ruidong Xiang, Emily L. Clark, Benjamin G. Cocks, Amanda J. Chamberlain, Iona M. MacLeod and Hans D. Daetwyler
    Citation: BMC Genomics 2020 21:720

    The Correction to this article has been published in BMC Genomics 2022 23:315

  37. Flammulina filiformis (previously known as Asian F. velutipes) is a popular commercial edible mushroom. Many bioactive compounds with medicinal effects, such as polysaccharides and sesquiterpenoids, have been iso...

    Authors: Juan Chen, Jia-Mei Li, Yan-Jing Tang, Ke Ma, Bing Li, Xu Zeng, Xiao-Bin Liu, Yang Li, Zhu-Liang Yang, Wei-Nan Xu, Bao-Gui Xie, Hong-Wei Liu and Shun-Xing Guo
    Citation: BMC Genomics 2020 21:719
  38. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Somayeh Kordafshari, Pollob Shil, Marc S. Marenda, Olusola M. Olaogun, Barbara Konsak-Ilievski, Jillian Disint and Amir H. Noormohammadi
    Citation: BMC Genomics 2020 21:718

    The original article was published in BMC Genomics 2020 21:598

  39. RNA sequencing is a powerful approach to quantify the genome-wide distribution of mRNA molecules in a population to gain deeper understanding of cellular functions and phenotypes. However, unlike eukaryotic ce...

    Authors: Chatarin Wangsanuwat, Kellie A. Heom, Estella Liu, Michelle A. O’Malley and Siddharth S. Dey
    Citation: BMC Genomics 2020 21:717
  40. To elucidate features of seed development, we investigated the transcriptome of a soybean isoline from the germplasm collection that contained an introgressed allele known as minute hilum (mi) which confers a sma...

    Authors: Gracia Zabala, Anupreet Kour and Lila O. Vodkin
    Citation: BMC Genomics 2020 21:716
  41. As global warming continues, heat stress (HS) is becoming an increasingly significant factor limiting plant growth and reproduction, especially for cool-season grass species. The objective of this study was to...

    Authors: Qi Yan, Xifang Zong, Fan Wu, Jie Li, Tiantian Ma, Yufeng Zhao, Qian Ma, Penglei Wang, Yanrong Wang and Jiyu Zhang
    Citation: BMC Genomics 2020 21:715
  42. Amylose accumulation in rice grains is controlled by genetic and environmental factors. Amylose content is a determinant factor of rice quality in terms of cooking and eating. Great variations in amylose conte...

    Authors: Hengdong Zhang, Jiana Chen, Shuanglü Shan, Fangbo Cao, Guanghui Chen, Yingbin Zou, Min Huang and Salah F. Abou-Elwafa
    Citation: BMC Genomics 2020 21:714
  43. Homeobox-containing genes encode crucial transcription factors involved in animal, plant and fungal development, and changes to homeobox genes have been linked to the evolution of novel body plans and morpholo...

    Authors: Yiqian Li, Wenyan Nong, Tobias Baril, Ho Yin Yip, Thomas Swale, Alexander Hayward, David E. K. Ferrier and Jerome H. L. Hui
    Citation: BMC Genomics 2020 21:713
  44. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Hye-Seon Kim, Jessica M. Lohmar, Mark Busman, Daren W. Brown, Todd A. Naumann, Hege H. Divon, Erik Lysøe, Silvio Uhlig and Robert H. Proctor
    Citation: BMC Genomics 2020 21:712

    The original article was published in BMC Genomics 2020 21:510

  45. Genes are regulated by various types of regulators and most of them are still unknown or unobserved. Current gene regulatory networks (GRNs) reverse engineering methods often neglect the unknown regulators and...

    Authors: Ming Shi, Sheng Tan, Xin-Ping Xie, Ao Li, Wulin Yang, Tao Zhu and Hong-Qiang Wang
    Citation: BMC Genomics 2020 21:711
  46. Belonging to lineage I of Brassicaceae, Camelina sativa is formed by two hybridizations of three species (three sub-genomes). The three sub-genomes were diverged from a common ancestor, likely derived from lineag...

    Authors: Zhikang Zhang, Fanbo Meng, Pengchuan Sun, Jiaqing Yuan, Ke Gong, Chao Liu, Weijie Wang and Xiyin Wang
    Citation: BMC Genomics 2020 21:705

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